PM Price
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Also affiliated: Central Arkansas Veterans Healthcare System (2016)
Research Areas
Biography and Research Information
OverviewAI-generated summary
PM Price's research focuses on the molecular mechanisms of programmed cell death. Their work has investigated the role of Cdk2 phosphorylation of Bcl-xL following cellular stress, examining how this modification converts Bcl-xL into a pro-apoptotic protein that mimics the function of Bax/Bak. Further studies explored how mimicking Cdk2 phosphorylation of Bcl-xL at specific sites, such as Ser73, leads to caspase activation and subsequent cleavage of Bcl-xL. These investigations contribute to understanding the complex signaling pathways that regulate apoptosis.
Metrics
- h-index: 2
- Publications: 3
- Citations: 45
Selected Publications
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Cdk2 phosphorylation of Bcl-xL after stress converts it to a pro-apoptotic protein mimicking Bax/Bak (2016)
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Mimicking Cdk2 phosphorylation of Bcl-xL at Ser73 results in caspase activation and Bcl-xL cleavage (2016)
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