Lei Guo Source Confirmed

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

High Impact

Assistant Professor

University of Arkansas at Fayetteville

faculty

35 h-index 488 pubs 3,887 cited

Research Areas

Electrochemical sensors and biosensors Nanoparticles: synthesis and applications Cancer-related molecular mechanisms research Cancer Genomics and Diagnostics Advanced biosensing and bioanalysis techniques Mesenchymal stem cell research Tissue Engineering and Regenerative Medicine Metal-organic frameworks (MOFs)

Links

ORCID Google Scholar Lab Website Research Group

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OverviewAI-generated summary

Lei Guo's research focuses on the development and application of novel sensing platforms and nanomaterials for diverse applications, including disease diagnostics and environmental remediation. Guo has investigated electrochemical biosensors utilizing functionalized materials like metal-organic frameworks (MOFs) and peptide-based platforms for the sensitive detection of cancer biomarkers, such as circulating tumor DNA (ctDNA) for non-small cell lung cancer (NSCLC).

Further research explores the application of engineered nanomaterials, including Zr-MOF functionalized nanochannels and ZrO2-modified seaweed residue, for tasks ranging from regenerative aptasensing to the removal of contaminants like fluorine and bacteria from wastewater, as well as uranium extraction. Guo has also contributed to studies on exosome-derived therapies for wound healing, investigating molecular pathways involved in angiogenesis, and has developed temperature-responsive nanomicelles with aggregation-induced emission (AIE) properties for the detection of metal ions.

With a significant publication record (488 publications, h-index 35, 3,887 citations), Guo is recognized as a highly cited researcher. Guo leads a research group and collaborates with other researchers at the University of Arkansas at Fayetteville, including Anne Lobitz.