Joonas A. Jamsen

Federal Grant PI

Assistant Professor

UAMS

Also affiliated: National Institutes of Health (2017–2022); City Of Hope National Medical Center (2012); University of Turku (2007–2012); National Institute of Environmental Health Sciences (2017–2022); City of Hope (2012); Beckman Research Institute (2012)

10 h-index 32 pubs 348 cited

Research Areas

Biomedical Subjects

Links

ORCID Research Group

OverviewAI-generated summary

Joonas A. Jamsen leads a research group at the University of Arkansas for Medical Sciences that investigates molecular mechanisms underlying DNA repair, particularly double-strand break repair. His work has been supported by two federal grants totaling $669,750 from the National Institutes of Health.

The first grant, from the National Institute of Environmental Health Sciences, provided $249,000 for research into the molecular architecture of oxidative stress-induced double-strand break repair. The second grant, from the National Institute of General Medical Sciences, awarded $420,750 to reveal DNA polymerase molecular strategies in end-joining double-strand break repair. These projects focus on understanding how cells repair DNA damage, a process critical for maintaining genomic stability and preventing disease.

Jamsen's publications include studies on the kinetics and structural basis of DNA repair polymerases, such as Polλ, and their role in processes like microhomology-mediated end-joining. His research also involves examining the insertion of oxidized nucleotides during DNA repair and the structural and regulatory aspects of protein complexes involved in cellular processes. He has authored 32 publications with 349 citations and maintains an h-index of 10.

Metrics

h-index: 10
Publications: 32
Citations: 348

Positions

Assistant Professor 2022–present

University of Arkansas for Medical Sciences Biochemistry and Molecular Biology ORCID
Visiting Fellow 2014–2022

National Institute of Environmental Health Sciences Genome Integrity & Structural Biology ORCID

Selected Publications

Observing DNA Polymerase Double Strand Break Synthesis (2025)

Structural Dynamics DOI OpenAlex
Author Correction: Polλ promotes microhomology-mediated end-joining (2023)

Nature Structural & Molecular Biology DOI OpenAlex
Polλ promotes microhomology-mediated end-joining (2022)

Nature Structural & Molecular Biology 29 citations DOI OpenAlex