Susanne Striegler
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Also affiliated: California Institute of Technology (1998); Universität Ulm (1996–2011); Auburn University (2005–2012)
Research Areas
Biomedical Subjects
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Biography and Research Information
OverviewAI-generated summary
Susanne Striegler's research focuses on the design and application of synthetic receptors, particularly those involving copper(II) complexes, for the selective recognition and transformation of carbohydrates. Her work investigates the molecular structure and activity of these complexes, exploring their capacity for catalysis and binding in aqueous solutions. This includes studies on how different ligand environments influence the coordination and discrimination of sugars, such as disaccharides.
Her federally funded projects have supported investigations into nanogels for carbohydrate catalysis, funded by the National Science Foundation (NSF) with a $525,000 grant where she served as PI. She also contributed as a Co-PI on an NSF grant for acquiring an MRI system to support accurate mass measurement for various scientific disciplines. Striegler has published extensively on carbohydrate recognition, copper complex chemistry, and related catalytic processes. Her scholarship metrics include an h-index of 19, with 64 publications and over 1,100 citations. She actively collaborates with researchers at the University of Arkansas at Fayetteville, including Babloo Sharma, Robert H. Coridan, Justin Reed DeMoulpied, and Jessica A. Killenbeck.
Metrics
- h-index: 19
- Publications: 64
- Citations: 1,127
Selected Publications
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Selective Hydrolysis of Heterooligosaccharides by Poly(acrylate) Gel Catalysts (2024)
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Developing Catalysts for the Hydrolysis of Glycosidic Bonds in Oligosaccharides Using a Spectrophotometric Screening Assay (2024)
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Nanogel Catalysts for the Hydrolysis of Underivatized Disaccharides Identified by a Fast Screening Assay (2023)
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Characterizing the Solvent‐Induced Inversion of Colloidal Aggregation During Electrophoretic Deposition (2022)
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Solvent-induced Inversion of Colloidal Aggregation During Electrophoretic Deposition (2022)
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Polarity and Critical Micelle Concentration of Surfactants Support the Catalytic Efficiency of Nanogels during Glycoside Hydrolyses (2022)
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Solvent-controlled synthesis of bulky and polar-bulky galactonoamidines (2022)
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Structure–Activity-Relationship Studies to Elucidate Sources of Antibacterial Activity of Modular Polyacrylate Microgels (2021)
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Microgel-Catalyzed Hydrolysis of Nonactivated Disaccharides (2020)
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Antimicrobial Activity of Microgels with an Immobilized Copper(II) Complex Linked to Cross-Linking and Composition (2020)
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Nonionic Surfactant Blends to Control the Size of Microgels and Their Catalytic Performance during Glycoside Hydrolyses (2020)
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Tailored Interactions of the Secondary Coordination Sphere Enhance the Hydrolytic Activity of Cross-Linked Microgels (2019)
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Biomimetic Glycoside Hydrolysis by a Microgel Templated with a Competitive Glycosidase Inhibitor (2018)
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Modulating the Catalytic Performance of an Immobilized Catalyst with Matrix Effects - A Critical Evaluation (2018)
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Crosslinked Microgels as Platform for Hydrolytic Catalysts (2018)
Federal Grants 2 $1,159,526 total
Collaboration Network
Top Collaborators
- Crosslinked Microgels as Platform for Hydrolytic Catalysts
- Modulating the Catalytic Performance of an Immobilized Catalyst with Matrix Effects - A Critical Evaluation
- Nonionic Surfactant Blends to Control the Size of Microgels and Their Catalytic Performance during Glycoside Hydrolyses
- Microgel-Catalyzed Hydrolysis of Nonactivated Disaccharides
- Tailored Interactions of the Secondary Coordination Sphere Enhance the Hydrolytic Activity of Cross-Linked Microgels
Showing 5 of 12 shared publications
- Biomimetic Glycoside Hydrolysis by a Microgel Templated with a Competitive Glycosidase Inhibitor
- Illuminating the binding interactions of galactonoamidines during the inhibition of β-galactosidase (E. coli)
- Discrimination of chiral copper( ii ) complexes upon binding of galactonoamidine ligands
- Arabinoamidine synthesis and its inhibition toward β-glucosidase (sweet almonds) in comparison to a library of galactonoamidines
- Picomolar inhibition of β-galactosidase (bovine liver) attributed to loop closure
Showing 5 of 6 shared publications
- Evaluating N-benzylgalactonoamidines as putative transition state analogs for β-galactoside hydrolysis
- Illuminating the binding interactions of galactonoamidines during the inhibition of β-galactosidase (E. coli)
- Structure–Activity Relationship of Highly Potent Galactonoamidine Inhibitors toward β-Galactosidase ( Aspergillus oryzae )
- Binuclear copper(II) complexes discriminating epimeric glycosides and α- and β-glycosidic bonds in aqueous solution
- Arabinoamidine synthesis and its inhibition toward β-glucosidase (sweet almonds) in comparison to a library of galactonoamidines
- Biomimetic Glycoside Hydrolysis by a Microgel Templated with a Competitive Glycosidase Inhibitor
- Evaluating N-benzylgalactonoamidines as putative transition state analogs for β-galactoside hydrolysis
- Picomolar inhibition of β-galactosidase (bovine liver) attributed to loop closure
- Evaluating hydrophobic galactonoamidines as transition state analogs for enzymatic β-galactoside hydrolysis
- Antimicrobial Activity of Microgels with an Immobilized Copper(II) Complex Linked to Cross-Linking and Composition
- Structure–Activity-Relationship Studies to Elucidate Sources of Antibacterial Activity of Modular Polyacrylate Microgels
- Microgel-Catalyzed Hydrolysis of Nonactivated Disaccharides
- Solvent-controlled synthesis of bulky and polar-bulky galactonoamidines
- Characterizing the Solvent‐Induced Inversion of Colloidal Aggregation During Electrophoretic Deposition
- Solvent-induced Inversion of Colloidal Aggregation During Electrophoretic Deposition
- Characterizing the Solvent‐Induced Inversion of Colloidal Aggregation During Electrophoretic Deposition
- Solvent-induced Inversion of Colloidal Aggregation During Electrophoretic Deposition
- Characterizing the Solvent‐Induced Inversion of Colloidal Aggregation During Electrophoretic Deposition
- Solvent-induced Inversion of Colloidal Aggregation During Electrophoretic Deposition
- Characterizing the Solvent‐Induced Inversion of Colloidal Aggregation During Electrophoretic Deposition
- Solvent-induced Inversion of Colloidal Aggregation During Electrophoretic Deposition
- Evaluating N-benzylgalactonoamidines as putative transition state analogs for β-galactoside hydrolysis
- Illuminating the binding interactions of galactonoamidines during the inhibition of β-galactosidase (E. coli)
- Structure–Activity Relationship of Highly Potent Galactonoamidine Inhibitors toward β-Galactosidase ( Aspergillus oryzae )
- Binuclear copper(II) complexes discriminating epimeric glycosides and α- and β-glycosidic bonds in aqueous solution