Deborah K. Hansen
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Also affiliated: Agricultural Research Service (2001); United States Food and Drug Administration (1990–2019); United States Department of Agriculture (2001); Indiana University Indianapolis (1983); Indiana University School of Medicine (1983); The University of Texas Health Science Center at Houston (2017)
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Deborah K. Hansen's research has focused on the assessment of toxicological effects, particularly concerning drug-induced hepatotoxicity and protection mechanisms. Her work has investigated the evaluation of potential therapeutic agents and their impact on liver health. Hansen has also explored the mechanisms underlying cellular responses to toxic exposures.
Metrics
- h-index: 29
- Publications: 99
- Citations: 2,333
Selected Publications
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Rebuttal to the comments by Dr. Yan Xu on the article “Transcript profiling in the testes and prostates of postnatal day 30 Sprague-Dawley rats exposed prenatally and lactationally to 2-hydroxy-4-methoxybenzophenone” (2019)
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Transcript profiling in the testes and prostates of postnatal day 30 Sprague-Dawley rats exposed prenatally and lactationally to 2-hydroxy-4-methoxybenzophenone (2018)
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Evaluation of Culture Time and Media in an In Vitro Testis Organ Culture System (2017)
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Evidence Favoring a Positive Feedback Loop for Physiologic Auto Upregulation of hnRNP-E1 during Prolonged Folate Deficiency in Human Placental Cells (2017)
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Transcriptomics analysis of early embryonic stem cell differentiation under osteoblast culture conditions: Applications for detection of developmental toxicity (2017)
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Effects of Culture Conditions on Maturation of Stem Cell‐Derived Cardiomyocytes (2016)
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Effects of silver nanoparticles on human and rat embryonic neural stem cells (2015)
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Developing osteoblasts as an endpoint for the mouse embryonic stem cell test (2015)
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Effects of Maternal and Lactational Exposure to 2‐Hydroxy‐4‐Methoxybenzone on Development and Reproductive Organs in Male and Female Rat Offspring (2015)
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Folic Acid (2014)
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Reevaluation of the Embryonic Stem Cell Test (2013)
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Cardiovascular Toxicity of Citrus aurantium in Exercised Rats (2013)
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Effect of Maternal and Lactational Exposure to Oxybenzone on Testes Development in Male Rats. (2012)
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Physiological effects following administration of Citrus aurantium for 28 days in rats (2012)
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Developmental toxicity of Citrus aurantium in rats (2011)
Collaboration Network
Top Collaborators
- Lack of attenuation of valproic acid‐induced effects by folinic acid in rat embryos in vitro
- Effect of supplemental folic acid on valproic acid‐induced embryotoxicity and tissue zinc levels in vivo
- Lack of embryotoxicity of homocysteine thiolactone in mouse embryos in vitro
- Alterations in maternal plasma corticosterone levels following treatment with phenytoin
- Prenatal neuroleptic exposure and growth stunting in the rat: An in vivo and in vitro examination of sensitive periods and possible mechanisms
Showing 5 of 15 shared publications
- Renal Effects of Fumonisin Mycotoxins in Animals
- Marginal Biotin Deficiency Is Teratogenic in ICR Mice
- Effects of Fumonisin B1 in Pregnant Rats. Part 2
- Effects of Fumonisin B1 in Pregnant Rats
- Target tissue specificity of retinoic acid‐induced stress proteins and malformations in mice
Showing 5 of 13 shared publications
- Effects of silver nanoparticles on human and rat embryonic neural stem cells
- Effects of Maternal and Lactational Exposure to 2‐Hydroxy‐4‐Methoxybenzone on Development and Reproductive Organs in Male and Female Rat Offspring
- Evaluation of Culture Time and Media in an In Vitro Testis Organ Culture System
- Developing osteoblasts as an endpoint for the mouse embryonic stem cell test
- Transcript profiling in the testes and prostates of postnatal day 30 Sprague-Dawley rats exposed prenatally and lactationally to 2-hydroxy-4-methoxybenzophenone
Showing 5 of 12 shared publications
- Effects of Maternal and Lactational Exposure to 2‐Hydroxy‐4‐Methoxybenzone on Development and Reproductive Organs in Male and Female Rat Offspring
- Developmental toxicology—new directions workshop: refining testing strategies and study designs
- Developing osteoblasts as an endpoint for the mouse embryonic stem cell test
- Transcript profiling in the testes and prostates of postnatal day 30 Sprague-Dawley rats exposed prenatally and lactationally to 2-hydroxy-4-methoxybenzophenone
- Transcriptomics analysis of early embryonic stem cell differentiation under osteoblast culture conditions: Applications for detection of developmental toxicity
Showing 5 of 7 shared publications
- Target tissue specificity of retinoic acid‐induced stress proteins and malformations in mice
- Retinoic acid induction of stress proteins in fetal mouse limb buds
- Retinoic acid-induced stress protein synthesis in the mouse
- Phenytoin-Induced Stress Protein Synthesis In Mouse Embryonic Tissue
- Dose-response of retinoic acid induced stress protein synthesis and teratogenesis in mice
Showing 5 of 6 shared publications
- Target tissue specificity of retinoic acid‐induced stress proteins and malformations in mice
- Retinoic acid induction of stress proteins in fetal mouse limb buds
- Retinoic acid-induced stress protein synthesis in the mouse
- Phenytoin-Induced Stress Protein Synthesis In Mouse Embryonic Tissue
- Dose-response of retinoic acid induced stress protein synthesis and teratogenesis in mice
Showing 5 of 6 shared publications
- Target tissue specificity of retinoic acid‐induced stress proteins and malformations in mice
- The in vitro embryotoxicity of 5‐fluorouracil in rat embryos
- Retinoic acid-induced stress protein synthesis in the mouse
- Embryotoxicity of Phenytoin in Adrenalectomized CD-1 Mice
- Reply to “comments on ‘target tissue specificity of retinoic acid‐induced stress proteins and malformations in mice’”
Showing 5 of 6 shared publications
- Target tissue specificity of retinoic acid‐induced stress proteins and malformations in mice
- Retinoic acid induction of stress proteins in fetal mouse limb buds
- Retinoic acid-induced stress protein synthesis in the mouse
- Dose-response of retinoic acid induced stress protein synthesis and teratogenesis in mice
- Reply to “comments on ‘target tissue specificity of retinoic acid‐induced stress proteins and malformations in mice’”
Showing 5 of 6 shared publications
- An Overview of Rodent Toxicities: Liver and Kidney Effects of Fumonisins and Fusarium moniliforme
- Effects of Fumonisin B1 in Pregnant Rats. Part 2
- Effects of Fumonisin B1 in Pregnant Rats
- Food and Drug Administration Proposed Testing Guidelines for Reproduction Studies
- Food and Drug Administration Proposed Testing Guidelines for Developmental Toxicity Studies
Showing 5 of 6 shared publications
- Behavioral effects of prenatal folate deficiency in mice
- Isolation and Characterization of a Folate Receptor mRNA-binding trans-Factor from Human Placenta
- Incrimination of Heterogeneous Nuclear Ribonucleoprotein E1 (hnRNP-E1) as a Candidate Sensor of Physiological Folate Deficiency
- Antisense modulation of the coding or regulatory sequence of the folate receptor (folate binding protein‐1) in mouse embryos leads to neural tube defects
- Evidence Favoring a Positive Feedback Loop for Physiologic Auto Upregulation of hnRNP-E1 during Prolonged Folate Deficiency in Human Placental Cells
Showing 5 of 6 shared publications
- Alterations in maternal plasma corticosterone levels following treatment with phenytoin
- Prenatal neuroleptic exposure and growth stunting in the rat: An in vivo and in vitro examination of sensitive periods and possible mechanisms
- Behavioral teratology and dominant lethal evaluation of nitrous oxide exposure in rats
- Embryotoxicity of Phenytoin in Adrenalectomized CD-1 Mice
- Developmental Neurotoxicity of Antiepileptic Drugs
Showing 5 of 6 shared publications
- Effects of Maternal and Lactational Exposure to 2‐Hydroxy‐4‐Methoxybenzone on Development and Reproductive Organs in Male and Female Rat Offspring
- Evaluation of Culture Time and Media in an In Vitro Testis Organ Culture System
- Transcript profiling in the testes and prostates of postnatal day 30 Sprague-Dawley rats exposed prenatally and lactationally to 2-hydroxy-4-methoxybenzophenone
- Effect of Maternal and Lactational Exposure to Oxybenzone on Testes Development in Male Rats.
- Rebuttal to the comments by Dr. Yan Xu on the article “Transcript profiling in the testes and prostates of postnatal day 30 Sprague-Dawley rats exposed prenatally and lactationally to 2-hydroxy-4-methoxybenzophenone”
- Effects of Maternal and Lactational Exposure to 2‐Hydroxy‐4‐Methoxybenzone on Development and Reproductive Organs in Male and Female Rat Offspring
- Transcript profiling in the testes and prostates of postnatal day 30 Sprague-Dawley rats exposed prenatally and lactationally to 2-hydroxy-4-methoxybenzophenone
- Reevaluation of the Embryonic Stem Cell Test
- Effect of Maternal and Lactational Exposure to Oxybenzone on Testes Development in Male Rats.
- Rebuttal to the comments by Dr. Yan Xu on the article “Transcript profiling in the testes and prostates of postnatal day 30 Sprague-Dawley rats exposed prenatally and lactationally to 2-hydroxy-4-methoxybenzophenone”
- Target tissue specificity of retinoic acid‐induced stress proteins and malformations in mice
- Retinoic acid induction of stress proteins in fetal mouse limb buds
- Retinoic acid-induced stress protein synthesis in the mouse
- Phenytoin-Induced Stress Protein Synthesis In Mouse Embryonic Tissue
- Reply to “comments on ‘target tissue specificity of retinoic acid‐induced stress proteins and malformations in mice’”
- Effects of Fumonisin B1 in Pregnant Rats. Part 2
- Effects of Fumonisin B1 in Pregnant Rats
- Food and Drug Administration Proposed Testing Guidelines for Reproduction Studies
- Food and Drug Administration Proposed Testing Guidelines for Developmental Toxicity Studies
- Lack of Embryotoxicity of Fumonisin B1 in New Zealand White Rabbits
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