Biography and Research Information
OverviewAI-generated summary
Ann Varghese's research focuses on the intersection of computational biology, structural analysis, and pharmacological development. Her recent publications investigate the structural features of SARS-CoV-2 papain-like protease for potential inhibition and explore the integration of molecular dynamics, docking, and machine learning to predict binders for this enzyme. Varghese has also contributed to understanding the κ opioid receptor, with implications for developing novel opioid analgesics. Her work includes the identification of biomarkers for central nervous system involvement in Myotonic dystrophy type 1. Varghese collaborates with researchers at the National Center for Toxicological Research, including Tucker A. Patterson, Fan Dong, Bailang Liu, and Aasma Aslam, with whom she has co-authored multiple publications. Her scholarship metrics include an h-index of 2 and 19 total citations across 4 publications.
Metrics
- h-index: 2
- Publications: 6
- Citations: 24
Selected Publications
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Integrating Molecular Dynamics, Molecular Docking, and Machine Learning for Predicting SARS-CoV-2 Papain-like Protease Binders (2025)
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Analysis of Structures of SARS-CoV-2 Papain-like Protease Bound with Ligands Unveils Structural Features for Inhibiting the Enzyme (2025)
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Decoding the κ Opioid Receptor (KOR): Advancements in Structural Understanding and Implications for Opioid Analgesic Development (2024)
Collaboration Network
Top Collaborators
Jie Liu
United States Food and Drug Administration
3 shared publications
In database
- Analysis of Structures of SARS-CoV-2 Papain-like Protease Bound with Ligands Unveils Structural Features for Inhibiting the Enzyme
- Integrating Molecular Dynamics, Molecular Docking, and Machine Learning for Predicting SARS-CoV-2 Papain-like Protease Binders
- Decoding the κ Opioid Receptor (KOR): Advancements in Structural Understanding and Implications for Opioid Analgesic Development
Tucker A. Patterson
United States Food and Drug Administration
3 shared publications
In database
- Analysis of Structures of SARS-CoV-2 Papain-like Protease Bound with Ligands Unveils Structural Features for Inhibiting the Enzyme
- Integrating Molecular Dynamics, Molecular Docking, and Machine Learning for Predicting SARS-CoV-2 Papain-like Protease Binders
- Decoding the κ Opioid Receptor (KOR): Advancements in Structural Understanding and Implications for Opioid Analgesic Development
Huixiao Hong
National Center for Toxicological Research
3 shared publications
In database
- Analysis of Structures of SARS-CoV-2 Papain-like Protease Bound with Ligands Unveils Structural Features for Inhibiting the Enzyme
- Integrating Molecular Dynamics, Molecular Docking, and Machine Learning for Predicting SARS-CoV-2 Papain-like Protease Binders
- Decoding the κ Opioid Receptor (KOR): Advancements in Structural Understanding and Implications for Opioid Analgesic Development
Wenjing Guo
United States Food and Drug Administration
2 shared publications
In database
- Analysis of Structures of SARS-CoV-2 Papain-like Protease Bound with Ligands Unveils Structural Features for Inhibiting the Enzyme
- Decoding the κ Opioid Receptor (KOR): Advancements in Structural Understanding and Implications for Opioid Analgesic Development
Fan Dong
United States Food and Drug Administration
2 shared publications
In database
- Analysis of Structures of SARS-CoV-2 Papain-like Protease Bound with Ligands Unveils Structural Features for Inhibiting the Enzyme
- Decoding the κ Opioid Receptor (KOR): Advancements in Structural Understanding and Implications for Opioid Analgesic Development
Bailang Liu
United States Food and Drug Administration
2 shared publications
In database
- Analysis of Structures of SARS-CoV-2 Papain-like Protease Bound with Ligands Unveils Structural Features for Inhibiting the Enzyme
- Decoding the κ Opioid Receptor (KOR): Advancements in Structural Understanding and Implications for Opioid Analgesic Development
S. Spendiff
1 shared publication
- P.203 Biomarkers for central nervous system involvement in Myotonic dystrophy type 1
Andrea K M Ross
1 shared publication
- P.203 Biomarkers for central nervous system involvement in Myotonic dystrophy type 1
H. Lochmüller
1 shared publication
- P.203 Biomarkers for central nervous system involvement in Myotonic dystrophy type 1
Zoe Li
United States Food and Drug Administration
1 shared publication
In database
- Decoding the κ Opioid Receptor (KOR): Advancements in Structural Understanding and Implications for Opioid Analgesic Development
Ruili Huang
National Center for Advancing Translational Sciences (US)
1 shared publication
- Decoding the κ Opioid Receptor (KOR): Advancements in Structural Understanding and Implications for Opioid Analgesic Development
Menghang Xia
National Institutes of Health (US)
1 shared publication
- Decoding the κ Opioid Receptor (KOR): Advancements in Structural Understanding and Implications for Opioid Analgesic Development
Nancy Chang
Center for Drug Evaluation and Research (US)
1 shared publication
- Decoding the κ Opioid Receptor (KOR): Advancements in Structural Understanding and Implications for Opioid Analgesic Development
Aasma Aslam
National Center for Toxicological Research
1 shared publication
In database
- Decoding the κ Opioid Receptor (KOR): Advancements in Structural Understanding and Implications for Opioid Analgesic Development
Similar Researchers
Based on overlapping research topics
Ari Filip
University of Arkansas for Medical Sciences
Protein Structure and Dynamics
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National Center for Toxicological Research
Protein Structure and Dynamics
Computational Drug Discovery Methods
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Sugunadevi Sakkiah
National Center for Toxicological Research
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James Aronson
University of Arkansas for Medical Sciences
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Michelle A. Johnson
University of Arkansas at Fayetteville
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Wenjing Guo
National Center for Toxicological Research
Protein Structure and Dynamics
Computational Drug Discovery Methods
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