Match tier Listed
Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-08

Ann Varghese

Researcher

Also affiliated: United States Food and Drug Administration (2024–2026); Food and Drug Administration (2026)

Unknown Researcher

3 h-index 7 pubs 28 cited

  • Machine Learning
  • SARS-CoV-2
  • Coronavirus Papain-Like Proteases
  • Humans
  • Ligands
  • Antiviral Agents
  • Binding Sites
  • Protease Inhibitors
  • Protein Binding
  • COVID-19
  • COVID-19 Drug Treatment
  • Molecular Dynamics Simulation
  • Molecular Docking Simulation
  • Coronavirus 3C Proteases
  • Analgesics, Opioid

Biography and Research Information

OverviewAI-generated summary

Ann Varghese's research focuses on understanding the molecular mechanisms of viral proteases, particularly those associated with SARS-CoV-2. Her recent work investigates the structures of SARS-CoV-2 papain-like protease when bound with various ligands, aiming to identify structural features that can inhibit the enzyme. She also explores the integration of computational methods, including molecular dynamics, molecular docking, and machine learning, for predicting binders to this protease. Varghese has also contributed to research on the κ opioid receptor, focusing on structural understanding and its implications for developing opioid analgesics. Her published work includes studies on biomarkers for neurological involvement in myotonic dystrophy type 1. Varghese has an h-index of 3 with 7 total publications and 28 citations.

Metrics

  • h-index: 3
  • Publications: 7
  • Citations: 28

Selected Publications

  • Structural insights into cannabinoid receptors CB1 and CB2: determinants of ligand selectivity (2026)
    Frontiers in Chemical Biology DOI OpenAlex
  • BERT-Based Models for Normalization of Adverse Drug Event Expressions in Social Media to Standard Medical Terminology for Drug Safety Analysis (2026)
    Big Data and Cognitive Computing DOI OpenAlex
  • Integrating Molecular Dynamics, Molecular Docking, and Machine Learning for Predicting SARS-CoV-2 Papain-like Protease Binders (2025)
    Molecules 11 citations DOI OpenAlex
  • Analysis of Structures of SARS-CoV-2 Papain-like Protease Bound with Ligands Unveils Structural Features for Inhibiting the Enzyme (2025)
    Molecules 13 citations DOI OpenAlex
  • Decoding the κ Opioid Receptor (KOR): Advancements in Structural Understanding and Implications for Opioid Analgesic Development (2024)
    Molecules 3 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

11 Collaborators 5 Institutions 1 Country

Top Collaborators

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