Bill Durham
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
University Professor Emeritus
Also affiliated: University of North Carolina at Chapel Hill (1996–2003); Goethe University Frankfurt (2008); Oklahoma State University (2000–2012); University of Illinois Urbana-Champaign (1998–2007); University of North Carolina at Greensboro (1988); Clarkson University (1974); San Diego Supercomputer Center (2002); Wayne State University (1979); University of L'Aquila (2008); University of Arkansas System (1993–1994); Idaho National Laboratory (2006); University of California San Diego (1996); Joint Center for Structural Genomics (2002); Institut de Chimie de Strasbourg (2008); Rice University (2007); Michigan State University (2002–2008)
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Bill Durham's research program focuses on the study of electron transfer processes, particularly in biological systems and through the use of ruthenium complexes. His work has investigated the kinetics and mechanisms of photoinduced electron transfer, often employing ruthenium(II) polypyridyl complexes as photosensitizers or labels.
His publications detail the synthesis and characterization of ruthenium-cytochrome c derivatives designed to probe electron transfer to the initial acceptor in cytochrome c oxidase. Durham has also explored the photoinduced electron transfer kinetics of various ruthenium-cytochrome c conjugates, collaborating with researchers such as Francis Millett, Lois Geren, Martha Scharlau, and Clayre Parson. His research has also included the photochemistry and photoisomerization of ruthenium complexes, as well as synthetic applications of photosubstitution reactions.
With an h-index of 38 and over 4,400 citations from 158 publications, Durham's scholarship reflects a sustained contribution to the fields of photochemistry, bioinorganic chemistry, and biophysics. His recent activity indicates continued engagement in research.
Metrics
- h-index: 36
- Publications: 148
- Citations: 4,268
Positions
-
University Professor Emeritus publications 1981–2023University of Arkansas at Fayetteville Institution web page
Selected Publications
-
Photoinduced electron transfer in cytochrome bc1: Dynamics of rotation of the Iron-sulfur protein during bifurcated electron transfer from ubiquinol to cytochrome c1 and cytochrome bL (2023)
-
Accelerated Evolution of Cytochrome c in Higher Primates, and Regulation of the Reaction between Cytochrome c and Cytochrome Oxidase by Phosphorylation (2022)
-
Definition of the Interaction Domain and Electron Transfer Route between Cytochrome c and Cytochrome Oxidase (2019)
-
Definition of the Electron Transfer Pathway between Cytochrome c and Cytochrome Oxidase (2018)
-
Proteo-lipobeads for the oriented encapsulation of membrane proteins (2015)
-
Gas chromatography–mass spectrometry of JWH-018 metabolites in urine samples with direct comparison to analytical standards (2013)
-
Design and use of photoactive ruthenium complexes to study electron transfer within cytochrome bc1 and from cytochrome bc1 to cytochrome c (2012)
-
Rapid characterization of lipids by MALDI MS. Part 2: Artifacts, ion suppression, and TLC MALDI imaging (2012)
-
Ruthenium Photoinitiation of Electron Transfer in the Rb. Sphaeroides Cytochrome bc1 Complex: Rotational dynamics of the iron-sulfur protein, diffusion of quinone between the Qo and Qi sites, and linkage between the two monomers (2012)
-
Geologic nitrogen and climate change in the geochemical budget of Kärkevagge, Swedish Lapland (2012)
-
Rapid characterization of lipids by MALDI MS. Part 1: Bacterial taxonomy and analysis of food oils (2012)
-
Design of photoactive ruthenium complexes to study electron transfer and proton pumping in cytochrome oxidase (2011)
-
Photoinitiated Electron Transfer within the Paracoccus denitrificans Cytochrome bc1 Complex: Mobility of the Iron–Sulfur Protein Is Modulated by the Occupant of the Qo Site (2011)
-
The acidic domain of cytochrome c1 in Paracoccus denitrificans, analogous to the acidic subunits in eukaryotic bc1 complexes, is not involved in the electron transfer reaction to its native substrate cytochrome c552 (2011)
-
Laser Desorption/Ionization Time‐of‐Flight Mass Spectrometry of Triacylglycerols and Other Components in Fingermark Samples* (2011)
Collaboration Network
Top Collaborators
- Design of a Ruthenium-Cytochrome c Derivative to Measure Electron Transfer to the Initial Acceptor in Cytochrome c Oxidase
- Photoinduced electron-transfer kinetics of singly labeled ruthenium bis(bipyridine) dicarboxybipyridine cytochrome c derivatives
- Definition of the Interaction Domain for Cytochrome con Cytochrome c Oxidase
- Genetic engineering of redox donor sites: measurement of intracomplex electron transfer between ruthenium-65-cytochrome b5 and cytochrome c
- Single Electron Reduction of Cytochrome c Oxidase Compound F: Resolution of Partial Steps by Transient Spectroscopy
Showing 5 of 45 shared publications
- Design of a Ruthenium-Cytochrome c Derivative to Measure Electron Transfer to the Initial Acceptor in Cytochrome c Oxidase
- Definition of the Interaction Domain for Cytochrome con Cytochrome c Oxidase
- Role of the Conserved Arginine Pair in Proton and Electron Transfer in CytochromecOxidase
- Design of a Ruthenium−Cytochrome c Derivative To Measure Electron Transfer to the Radical Cation and Oxyferryl Heme in Cytochrome c Peroxidase
- Single-electron photoreduction of the PM intermediate of cytochrome c oxidase
Showing 5 of 18 shared publications
- Design of a Ruthenium-Labeled Cytochrome c Derivative to Study Electron Transfer with the Cytochrome bc1 Complex
- Photoinduced Electron Transfer between the Rieske Iron-Sulfur Protein and Cytochrome c1 in theRhodobacter sphaeroides Cytochromebc1 Complex
- Definition of the Interaction Domain for Cytochrome con the Cytochrome bc 1 Complex
- Effect of Famoxadone on Photoinduced Electron Transfer between the Iron-Sulfur Center and Cytochrome c 1 in the Cytochrome bc 1 Complex
- Intracomplex electron transfer between ruthenium-cytochrome c derivatives and cytochrome c1.
Showing 5 of 8 shared publications
- Definition of the Interaction Domain for Cytochrome con Cytochrome c Oxidase
- Role of the Conserved Arginine Pair in Proton and Electron Transfer in CytochromecOxidase
- Mutants of the CuA Site in Cytochrome c Oxidase of Rhodobacter sphaeroides: II. Rapid Kinetic Analysis of Electron Transfer
- Proton-Dependent Electron Transfer from CuA to Heme a and Altered EPR Spectra in Mutants Close to Heme a of Cytochrome Oxidase
- Definition of the Interaction Domain and Electron Transfer Route between Cytochrome c and Cytochrome Oxidase
Showing 5 of 8 shared publications
- Reducing fragmentation observed in the matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometric analysis of triacylglycerols in vegetable oils
- Rapid characterization of edible oils by direct matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry analysis using triacylglycerols
- Laser Desorption/Ionization Time‐of‐Flight Mass Spectrometry of Triacylglycerols and Other Components in Fingermark Samples*
- A rapid separation technique for overcoming suppression of triacylglycerols by phosphatidylcholine using MALDI-TOF MS
- Gas chromatography–mass spectrometry of JWH-018 metabolites in urine samples with direct comparison to analytical standards
Showing 5 of 7 shared publications
- Design of a Ruthenium-Cytochrome c Derivative to Measure Electron Transfer to the Initial Acceptor in Cytochrome c Oxidase
- Design of a Ruthenium−Cytochrome c Derivative To Measure Electron Transfer to the Radical Cation and Oxyferryl Heme in Cytochrome c Peroxidase
- Design of a Ruthenium-Labeled Cytochrome c Derivative to Study Electron Transfer with the Cytochrome bc1 Complex
- Intracomplex electron transfer between ruthenium-65-cytochrome b5 and position-82 variants of yeast iso-1-cytochrome c
- Control of Formation and Dissociation of the High-Affinity Complex between Cytochrome c and Cytochrome c Peroxidase by Ionic Strength and the Low-Affinity Binding Site
Showing 5 of 7 shared publications
- Reducing fragmentation observed in the matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometric analysis of triacylglycerols in vegetable oils
- Laser Desorption/Ionization Time‐of‐Flight Mass Spectrometry of Triacylglycerols and Other Components in Fingermark Samples*
- A rapid separation technique for overcoming suppression of triacylglycerols by phosphatidylcholine using MALDI-TOF MS
- Gas chromatography–mass spectrometry of JWH-018 metabolites in urine samples with direct comparison to analytical standards
- Rapid characterization of lipids by MALDI MS. Part 1: Bacterial taxonomy and analysis of food oils
Showing 5 of 6 shared publications
- Definition of the Interaction Domain for Cytochrome con Cytochrome c Oxidase
- Single Electron Reduction of Cytochrome c Oxidase Compound F: Resolution of Partial Steps by Transient Spectroscopy
- Design of a Ruthenium−Cytochrome c Derivative To Measure Electron Transfer to the Radical Cation and Oxyferryl Heme in Cytochrome c Peroxidase
- Mutants of the CuA Site in Cytochrome c Oxidase of Rhodobacter sphaeroides: II. Rapid Kinetic Analysis of Electron Transfer
- Control of Formation and Dissociation of the High-Affinity Complex between Cytochrome c and Cytochrome c Peroxidase by Ionic Strength and the Low-Affinity Binding Site
Showing 5 of 6 shared publications
- Definition of the Interaction Domain for Cytochrome con Cytochrome c Oxidase
- Single Electron Reduction of Cytochrome c Oxidase Compound F: Resolution of Partial Steps by Transient Spectroscopy
- Definition of the Interaction Domain for Cytochrome con the Cytochrome bc 1 Complex
- Direct measurement of proton release by cytochrome c oxidase in solution during the F→O transition
- Exposure of Bovine Cytochrome c Oxidase to High Triton X-100 or to Alkaline Conditions Causes a Dramatic Change in the Rate of Reduction of Compound F
Showing 5 of 6 shared publications
- Design of a Ruthenium-Cytochrome c Derivative to Measure Electron Transfer to the Initial Acceptor in Cytochrome c Oxidase
- Design of a Ruthenium−Cytochrome c Derivative To Measure Electron Transfer to the Radical Cation and Oxyferryl Heme in Cytochrome c Peroxidase
- Design of a Ruthenium-Labeled Cytochrome c Derivative to Study Electron Transfer with the Cytochrome bc1 Complex
- Intracomplex electron transfer between ruthenium-65-cytochrome b5 and position-82 variants of yeast iso-1-cytochrome c
- Identifying the Physiological Electron Transfer Site of Cytochrome c Peroxidase by Structure-Based Engineering
Showing 5 of 6 shared publications
- Photoinduced Electron Transfer between the Rieske Iron-Sulfur Protein and Cytochrome c1 in theRhodobacter sphaeroides Cytochromebc1 Complex
- Definition of the Interaction Domain for Cytochrome con the Cytochrome bc 1 Complex
- Effect of Famoxadone on Photoinduced Electron Transfer between the Iron-Sulfur Center and Cytochrome c 1 in the Cytochrome bc 1 Complex
- Photoinduced electron transfer in cytochrome bc1: Dynamics of rotation of the Iron-sulfur protein during bifurcated electron transfer from ubiquinol to cytochrome c1 and cytochrome bL
- Ruthenium Photoinitiation of Electron Transfer in the Rb. Sphaeroides Cytochrome bc1 Complex: Rotational dynamics of the iron-sulfur protein, diffusion of quinone between the Qo and Qi sites, and linkage between the two monomers
Showing 5 of 6 shared publications
- Design and use of photoactive ruthenium complexes to study electron transfer within cytochrome bc1 and from cytochrome bc1 to cytochrome c
- Photoinitiated Electron Transfer within the Paracoccus denitrificans Cytochrome bc1 Complex: Mobility of the Iron–Sulfur Protein Is Modulated by the Occupant of the Qo Site
- The acidic domain of cytochrome c1 in Paracoccus denitrificans, analogous to the acidic subunits in eukaryotic bc1 complexes, is not involved in the electron transfer reaction to its native substrate cytochrome c552
- Photoinduced electron transfer in cytochrome bc1: Dynamics of rotation of the Iron-sulfur protein during bifurcated electron transfer from ubiquinol to cytochrome c1 and cytochrome bL
- Ruthenium Photoinitiation of Electron Transfer in the Rb. Sphaeroides Cytochrome bc1 Complex: Rotational dynamics of the iron-sulfur protein, diffusion of quinone between the Qo and Qi sites, and linkage between the two monomers
Showing 5 of 6 shared publications
- Electron transfer from cytochromeb 5 to cytochromec
- Comparison of laser desorption and matrix-assisted laser desorption/ionization for ruthenium and osmium trisbipyridine complexes using Fourier transform mass spectrometry
- Intramolecular electron-transfer reactions of cytochrome b5 covalently bonded to ruthenium(II) polypyridine complexes: reorganizational energy and pressure effects
- Ruthenium trisbipyridine as a candidate for gas‐phase spectroscopic studies in a Fourier transform mass spectrometer
- Design of instrumentation for probing changes in electrospray droplets via the Stern–Volmer relationship
- Laser Desorption/Ionization Time‐of‐Flight Mass Spectrometry of Triacylglycerols and Other Components in Fingermark Samples*
- A rapid separation technique for overcoming suppression of triacylglycerols by phosphatidylcholine using MALDI-TOF MS
- Gas chromatography–mass spectrometry of JWH-018 metabolites in urine samples with direct comparison to analytical standards
- Rapid characterization of lipids by MALDI MS. Part 1: Bacterial taxonomy and analysis of food oils
- Rapid characterization of lipids by MALDI MS. Part 2: Artifacts, ion suppression, and TLC MALDI imaging
- Single Electron Reduction of Cytochrome c Oxidase Compound F: Resolution of Partial Steps by Transient Spectroscopy
- Single-electron photoreduction of the PM intermediate of cytochrome c oxidase
- Direct measurement of proton release by cytochrome c oxidase in solution during the F→O transition
- Exposure of Bovine Cytochrome c Oxidase to High Triton X-100 or to Alkaline Conditions Causes a Dramatic Change in the Rate of Reduction of Compound F
- C2/2 Rapid kinetic studies of electron transfer in cytochrome oxidase