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Presence Current · Arkansas
Last published 2021
Sources OpenAlex · ORCID
Refreshed 2026-08-08

Charles E. Hay

Researcher

UAMS

Also affiliated: Children's Hospital of Philadelphia (2020); University of Pennsylvania (2020)

Faculty Researcher

2 h-index 14 pubs 39 cited

Research Areas

Biomedical Subjects

  • Dependovirus
  • Animals
  • Male
  • Methamphetamine
  • Mice, Inbred BALB C
  • Artificial Gene Fusion
  • Amphetamine-Related Disorders
  • Mice
  • Single-Chain Antibodies
  • Genetic Vectors
  • Central Nervous System Stimulants
  • Immunoglobulin Fc Fragments
  • Locomotion
  • Genetic Therapy

Links

ORCID

OverviewAI-generated summary

Charles E. Hay's research investigates the impact of drug exposure on the immune system. His work has explored how antibody gene therapy can counteract the immunosuppressive effects of substances like MDMA in animal models. This research contributes to understanding the complex interactions between pharmacological agents and peripheral immune responses.

Metrics

  • h-index: 2
  • Publications: 14
  • Citations: 39

Selected Publications

  • Antibody Gene Therapy Mitigates the immunosuppressive effects of 3,4‐Methylenedioxymethamphetamine (MDMA) in the periphery of Male BALB/c Mice (2021)
    The FASEB Journal DOI OpenAlex
  • Antibody Gene Therapy Mitigates Adverse Immunological Effects of 3,4‐Methylenedioxymethamphetamine (MDMA) in Male BALB/c Mice (2020)
    The FASEB Journal DOI OpenAlex
  • The Development and Characterization of an scFv-Fc Fusion–Based Gene Therapy to Reduce the Psychostimulant Effects of Methamphetamine Abuse (2020)
    Journal of Pharmacology and Experimental Therapeutics 28 citations DOI OpenAlex
  • AAV‐7F9‐Fc Protects Against METH‐Induced Hyperthermia and Decreases in Blood Brain Barrier Tight Junction Expression in a Rodent Model (2019)
    The FASEB Journal DOI OpenAlex
  • The development and characterization of an scFv-Fc fusion based gene therapy to reduce the psychostimulant effects of methamphetamine abuse (2019)
    bioRxiv (Cold Spring Harbor Laboratory) 1 citation DOI OpenAlex
  • Anti‐Methamphetamine Antibody Gene Therapy Ameliorates Methamphetamine‐induced Locomotor Effects in Mice for 8 Months after a Single Treatment (2018)
    The FASEB Journal DOI OpenAlex
  • Anti‐Methamphetamine Antibody Gene Therapy Protects Against Some METH‐Induced Inflammation (2018)
    The FASEB Journal DOI OpenAlex
  • Development and testing of AAV-delivered single-chain variable fragments for the treatment of methamphetamine abuse (2018)
    PLoS ONE 6 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

3 Collaborators 2 Institutions 1 Country

Top Collaborators

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