Christian K. Tipsmark
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Also affiliated: University of Hawaiʻi at Mānoa (2010–2016); University of Hawaii System (2010–2016); North Carolina State University (2004–2008); University of Southern Denmark (2000–2012); Hawaii Institute of Marine Biology (2010–2016)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Christian K. Tipsmark's research focuses on the physiological and molecular mechanisms underlying osmoregulation in fish, particularly in response to changes in salinity. His work investigates the expression and function of key ion transporters, such as the Na+,K+-ATPase and Na+,K+,2Cl− cotransporter, in various fish species including Atlantic salmon (Salmo salar), brown trout (Salmo trutta), and hybrid striped bass. Tipsmark's studies have examined how these transporters are regulated at the gene and protein level during critical life stages like smoltification and acclimation to different water salinities.
His publications detail the cellular localization and quantification of Na+,K+-ATPase isoforms in fish gills, exploring how salinity changes influence their expression patterns. Furthermore, his research extends to the role of aquaporins and claudins in osmoregulatory tissues, providing insights into the complex molecular machinery that allows fish to maintain internal water and electrolyte balance in diverse aquatic environments. Tipsmark's scholarship metrics include an h-index of 30, with over 2,390 citations across 53 publications, indicating a significant contribution to his field.
Metrics
- h-index: 30
- Publications: 53
- Citations: 2,396
Selected Publications
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Salt secretion by the gill of marine teleost fishes (2023)
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Drinking and Water Handling in the Medaka Intestine: A Possible Role of Claudin-15 in Paracellular Absorption? (2020)
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Salinity-dependent expression of ncc2 in opercular epithelium and gill of mummichog (Fundulus heteroclitus) (2020)
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Differential Expression and Localization of Branchial AQP1 and AQP3 in Japanese Medaka (Oryzias latipes) (2019)
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Prolactin controls Na+,Cl− cotransporter via Stat5 pathway in the teleost gill (2018)
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Salinity‐Dependent Expression of ncc‐like 2 in the Gill and Opercular Epithelium of Euryhaline Killifish (2017)
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Claudin-10isoform expression and cation selectivity change with salinity in salt-secreting epithelia ofF. heteroclitus (2017)
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Branchial claudin expression in response to freshwater and seawater acclimation in Japanese medaka (Oryzias latipes) (2017)Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology OpenAlex
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Prolactin and cortisol regulate branchial claudin expression in Japanese medaka (2016)
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Does Japanese medaka (Oryzias latipes) exhibit a gill Na+/K+-ATPase isoform switch during salinity change? (2016)
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Regulation of gill claudin paralogs by salinity, cortisol and prolactin in Mozambique tilapia (Oreochromis mossambicus) (2016)
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Role of the GH-IGF-1 system in Atlantic salmon and rainbow trout postsmolts at elevated water temperature (2015)
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Functional dynamics of claudin expression in Japanese medaka (Oryzias latipes): Response to environmental salinity (2015)
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Corrigendum to “Nutritional status and growth hormone regulate insulin-like growth factor binding protein (igfbp) transcripts in Mozambique tilapia” [Gen. Comp. Endocrinol. 207 (2014) 66–73] (2015)
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Sexual maturation and changes in water and salt transport components in the kidney and intestine of three-spined stickleback (Gasterosteus aculeatus L.) (2015)
Collaboration Network
Top Collaborators
- Aquaporin expression in the Japanese medaka (Oryzias latipes, Temminck & Schlegel) in FW and SW: challenging the paradigm for intestinal water transport?
- Functional dynamics of claudin expression in Japanese medaka (Oryzias latipes): Response to environmental salinity
- Tricellulin, occludin and claudin-3 expression in salmon intestine and kidney during salinity adaptation
- Does Japanese medaka (Oryzias latipes) exhibit a gill Na+/K+-ATPase isoform switch during salinity change?
- Functional characterization and localization of a gill-specific claudin isoform in Atlantic salmon
Showing 5 of 10 shared publications
- Switching of Na+, K+-ATPase isoforms by salinity and prolactin in the gill of a cichlid fish
- Dynamic gene expression of GH/PRL-family hormone receptors in gill and kidney during freshwater-acclimation of Mozambique tilapia
- Nutritional status and growth hormone regulate insulin-like growth factor binding protein (igfbp) transcripts in Mozambique tilapia
- Claudin-10isoform expression and cation selectivity change with salinity in salt-secreting epithelia ofF. heteroclitus
- Regulation of gill claudin paralogs by salinity, cortisol and prolactin in Mozambique tilapia (Oreochromis mossambicus)
Showing 5 of 8 shared publications
- Functional dynamics of claudin expression in Japanese medaka (Oryzias latipes): Response to environmental salinity
- Does Japanese medaka (Oryzias latipes) exhibit a gill Na+/K+-ATPase isoform switch during salinity change?
- Prolactin and cortisol regulate branchial claudin expression in Japanese medaka
- Transepithelial resistance and claudin expression in trout RTgill-W1 cell line: Effects of osmoregulatory hormones
- Prolactin controls Na+,Cl− cotransporter via Stat5 pathway in the teleost gill
Showing 5 of 7 shared publications
- Switching of Na+, K+-ATPase isoforms by salinity and prolactin in the gill of a cichlid fish
- Dynamic gene expression of GH/PRL-family hormone receptors in gill and kidney during freshwater-acclimation of Mozambique tilapia
- Nutritional status and growth hormone regulate insulin-like growth factor binding protein (igfbp) transcripts in Mozambique tilapia
- Regulation of gill claudin paralogs by salinity, cortisol and prolactin in Mozambique tilapia (Oreochromis mossambicus)
- Corrigendum to “Nutritional status and growth hormone regulate insulin-like growth factor binding protein (igfbp) transcripts in Mozambique tilapia” [Gen. Comp. Endocrinol. 207 (2014) 66–73]
- Switching of Na+, K+-ATPase isoforms by salinity and prolactin in the gill of a cichlid fish
- Dynamic gene expression of GH/PRL-family hormone receptors in gill and kidney during freshwater-acclimation of Mozambique tilapia
- Nutritional status and growth hormone regulate insulin-like growth factor binding protein (igfbp) transcripts in Mozambique tilapia
- Corrigendum to “Nutritional status and growth hormone regulate insulin-like growth factor binding protein (igfbp) transcripts in Mozambique tilapia” [Gen. Comp. Endocrinol. 207 (2014) 66–73]
- Switching of Na+, K+-ATPase isoforms by salinity and prolactin in the gill of a cichlid fish
- Nutritional status and growth hormone regulate insulin-like growth factor binding protein (igfbp) transcripts in Mozambique tilapia
- Regulation of gill claudin paralogs by salinity, cortisol and prolactin in Mozambique tilapia (Oreochromis mossambicus)
- Corrigendum to “Nutritional status and growth hormone regulate insulin-like growth factor binding protein (igfbp) transcripts in Mozambique tilapia” [Gen. Comp. Endocrinol. 207 (2014) 66–73]
- Does Japanese medaka (Oryzias latipes) exhibit a gill Na+/K+-ATPase isoform switch during salinity change?
- Prolactin and cortisol regulate branchial claudin expression in Japanese medaka
- Differential Expression and Localization of Branchial AQP1 and AQP3 in Japanese Medaka (Oryzias latipes)
- Prolactin controls Na+,Cl− cotransporter via Stat5 pathway in the teleost gill
- Differential Expression and Localization of Branchial AQP1 and AQP3 in Japanese Medaka (Oryzias latipes)
- Prolactin controls Na+,Cl− cotransporter via Stat5 pathway in the teleost gill
- Drinking and Water Handling in the Medaka Intestine: A Possible Role of Claudin-15 in Paracellular Absorption?
- Nutritional status and growth hormone regulate insulin-like growth factor binding protein (igfbp) transcripts in Mozambique tilapia
- Corrigendum to “Nutritional status and growth hormone regulate insulin-like growth factor binding protein (igfbp) transcripts in Mozambique tilapia” [Gen. Comp. Endocrinol. 207 (2014) 66–73]
- Nutritional status and growth hormone regulate insulin-like growth factor binding protein (igfbp) transcripts in Mozambique tilapia
- Corrigendum to “Nutritional status and growth hormone regulate insulin-like growth factor binding protein (igfbp) transcripts in Mozambique tilapia” [Gen. Comp. Endocrinol. 207 (2014) 66–73]
- Nutritional status and growth hormone regulate insulin-like growth factor binding protein (igfbp) transcripts in Mozambique tilapia
- Corrigendum to “Nutritional status and growth hormone regulate insulin-like growth factor binding protein (igfbp) transcripts in Mozambique tilapia” [Gen. Comp. Endocrinol. 207 (2014) 66–73]
- Aquaporin expression in the Japanese medaka (Oryzias latipes, Temminck & Schlegel) in FW and SW: challenging the paradigm for intestinal water transport?
- Transepithelial resistance and claudin expression in trout RTgill-W1 cell line: Effects of osmoregulatory hormones
- Regulation of gill claudin paralogs by salinity, cortisol and prolactin in Mozambique tilapia (Oreochromis mossambicus)
- Transepithelial resistance and claudin expression in trout RTgill-W1 cell line: Effects of osmoregulatory hormones
- Regulation of gill claudin paralogs by salinity, cortisol and prolactin in Mozambique tilapia (Oreochromis mossambicus)
- Transepithelial resistance and claudin expression in trout RTgill-W1 cell line: Effects of osmoregulatory hormones
- Sexual maturation and changes in water and salt transport components in the kidney and intestine of three-spined stickleback (Gasterosteus aculeatus L.)
- Drinking and Water Handling in the Medaka Intestine: A Possible Role of Claudin-15 in Paracellular Absorption?
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