Fred T. Caldwell
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Also affiliated: National Institutes of Health (1998); Arkansas Children's Hospital (1979–1996); State University of New York (1968); SUNY Upstate Medical University (1962–1969); Washington University in St. Louis (1959); University of Arkansas Medical Center (1969–1999); John B. Pierce Laboratory (1967); John L. McClellan Memorial Veterans Hospital (1973); Arkansas Department of Agriculture (1971–1988); Syracuse University (1968)
Formerly Arkansas Affiliated with UAMS through 2000.
Research Areas
Biomedical Subjects
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Biography and Research Information
OverviewAI-generated summary
Fred T. Caldwell's research has focused on the metabolic responses to thermal trauma and thermoregulation in various animal models and human subjects. His work has investigated the impact of different environmental temperatures and physiological states, such as thyroprivic conditions in rats, on metabolic responses. Caldwell has also explored methods for inducing and dissolving gallstones in mice through dietary interventions. His publications include studies on the critical evaluation of resuscitation solutions for severely burned children and the effect of dressings on energy metabolism in burn patients.
Caldwell has contributed to the understanding of body temperature regulation, notably in studies involving the blue-tongued lizard. His research methodology has included the development of specialized equipment, such as a calorimeter designed for simultaneous determination of heat production and loss in rats. With a career spanning numerous publications and a significant citation count, his work has been recognized with a high-impact researcher designation.
Metrics
- h-index: 25
- Publications: 96
- Citations: 1,623
Selected Publications
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Polyclonal antibodies to rat interleukin-6 attenuate fever in rats after burn injuries: A preliminary report (2000)
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Humoral versus Neural Pathways for Fever Production in Rats after Administration of Lipopolysaccharide (1999)
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The effect of indomethacin on the cytokine cascade and body temperature following burn injury in rats (1999)
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Vagotomy modifies but does not eliminate the increase in body temperature following burn injury in rats (1999)
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Calorigenic Response of Burned Rats with Adrenal Medullectomies to Catecholamines (1998)
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Studies on the Mechanism of Fever after Intravenous Administration of Endotoxin (1998)
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Chronic Indomethacin Administration Blocks Increased Body Temperature After Burn Injury in Rats (1998)
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Pathogenesis of Fever in a Rat Burn Model (1997)
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Manipulation of the Inflammatory Response to Burn Injury (1997)
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Sequential Excision And Grafting of the Burn Injuries of 1507 Patients Treated Between 1967 and 1986: End Results And the Determinants of Death (1996)
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Effect of adrenal medullectomy on responses in heat production, plasma catecholamines and body temperature of burned rats to changes in the temperature of the hypothalamus (1995)
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Effect of alpha adrenergic blockade on thermoregulation in adrenal demedullated burned rats (1995)
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The Response in Heat Production, Plasma Catecholamines, and Body Temperature of Burned Rats to Hypothalamic Temperature Displacement (1994)
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The Interrelationships Between Wound Management, Thermal Stress, Energy Metabolism, and Temperature Profiles of Patients With Burns (1994)
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Guinea Pigs With Large Burns are Consistently Hypermetabolic Without an Associated Increment in Rectal Temperature (1993)
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