Guido J. K. Tricot
Professor
Also affiliated: Leiden University (1981); University of Iowa (2012–2023); University of Maryland, Baltimore (1999–2004); BC Cancer Agency (2013); Arkansas Children's Hospital (1998); University of Minnesota (1985); Hackensack University Medical Center (2003); NewYork–Presbyterian Hospital (2009); Central South University (2023); Radboud University Nijmegen (1984); Emory University (1993); Inserm (1981); Oregon Health & Science University (2007); University of Basel (2005); Medical College of Wisconsin (2003–2018); Cornell University (2009); University of Utah (2008–2019); Rega Institute for Medical Research (1983–1986); Indiana University Hospital (1989–1990); University of Perugia (1983); University of Arkansas Medical Center (1996–2023); Leiden University Medical Center (1981–1982); Universitair Ziekenhuis Leuven (1984–1987); Huntsman Cancer Institute (2009–2019); University of Iowa Hospitals and Clinics (2013–2019); Statistics Belgium (1981); Saint Vincent Health System (2003); University Medical Center (1992); Moffitt Cancer Center (2000); Institut National de Recherche en Santé Publique (2003); Fred Hutch Cancer Center (1997–2013); Acentech (United States) (1998); Central Arkansas Veterans Healthcare System (2001–2002); Cancer Research And Biostatistics (2003–2015); Carver Bible College (2015); Indiana Cancer Consortium (1988); Dana-Farber Cancer Institute (2003); Indiana University Bloomington (1989–1994); Myeloma UK (2007–2009); Walther Cancer Foundation (1990); University of Applied Management Studies (2024); Cancer Research Center (1990–2002); Winthrop Rockefeller Foundation (2020–2025); Frederick National Laboratory for Cancer Research (1997); Hôtel-Dieu de Paris (1980); Christ Hospital (1993); University of Minnesota Medical Center (1985); Urology of Indiana (1986); System Biosciences (United States) (1995); National Cancer Institute (1997–2013); Hôpital Saint-Louis (1981–2015); Millennium Engineering and Integration (United States) (2005); Center for Cancer Research (1997); John L. McClellan Memorial Veterans Hospital (1994); Avalon Pharma (United States) (2007); Third Xiangya Hospital (2023); Iowa City Public Library (2016); International Myeloma Foundation (2015); Arkansas Department of Agriculture (2000–2002); SWOG Cancer Research Network (2000); U-M Rogel Cancer Center (1999–2004); University of Iowa Holden Comprehensive Cancer Center (2015); Indiana University School of Medicine (1987–1993); Bristol-Myers Squibb (Switzerland) (2001); University of Oklahoma Health Sciences Center (2005); The Ohio State University (2007); Indiana University – Purdue University Indianapolis (1986–1996); Indiana University (1989–1993); University of Baltimore (2000); Science Applications International Corporation (United States) (1997); University of Bologna (2006); UCLouvain (1984); Stanford University (2007); KU Leuven (1982–2015)
Internal Med, College of Medicine
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Guido J. K. Tricot's research focuses on multiple myeloma, a hematologic malignancy. His work has investigated various aspects of the disease, including its molecular classification, gene expression profiling, and risk stratification. He has also explored therapeutic strategies such as hematopoietic stem cell transplantation and the use of agents like thalidomide and bortezomib.
Tricot has contributed to the development of response criteria for multiple myeloma and has examined the graft-versus-myeloma effect. His research has been published in numerous peer-reviewed journals, and he holds an h-index of 96 with over 36,000 citations from more than 700 publications. He maintains an active research group and collaborates with colleagues at the University of Arkansas for Medical Sciences, including Fenghuang Zhan and John D. Shaughnessy.
His scholarly contributions have led to his designation as a highly cited researcher. Tricot's work has been instrumental in advancing the understanding and treatment of multiple myeloma.
Metrics
- h-index: 96
- Publications: 712
- Citations: 36,453
Positions
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Professor publications 1994–2025University of Arkansas for Medical Sciences Internal Med, College of Medicine Institutional directory
Selected Publications
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Polyclonal plasma cell (PolyPC) signature as a key indicator for predicting the progression of MGUS to multiple myeloma (2025)
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Long-Term Follow-Up of Patients With Multiple Myeloma Treated on Earlier Total Therapy Protocols (2025)
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Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption (2025)
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Long-term follow-up of Total Therapy IV: a phase 3 clinical trial for standard-risk multiple myeloma (2024)
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Identification of Risk Factors for Myeloma Progression in African American Patients (2024)
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The Low-Bone (LB) Subtype of Multiple Myeloma Exhibits an Inferior Outcome in African Americans (2024)
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Multi-Omics Reveal Immune Microenvironment Alterations in Multiple Myeloma and Its Precursor Stages (2024)
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Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages (2024)
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Psychological Impact in Individuals with Monoclonal Gammopathy of Undetermined Significance and Smoldering Multiple Myeloma (2024)
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Second primary malignancies after tandem autologous hematopoietic stem cell transplantation for multiple myeloma (2024)
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A Risk Stratification System in Myeloma Patients with Autologous Stem Cell Transplantation (2024)
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Prognostic value of ferritin in ASCT MM patients: integration with GEP models and ISS series systems (2024)
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Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth (2024)
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Three years of maintenance with VRD in multiple myeloma: results of total therapy IIIB with a 15-year follow-up (2023)
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High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma (2023)
Grants & Funding
As listed on this researcher's institutional profile.
- Gene expression profiling vs MRD assessment in Myeloma NIH Principal Investigator
- UARK 2003-01, Stem Cell Mobilization and Transplantation of Proven and/or Predicted Poor Mobilizers with Mutliple Myeloma AnorMED, Inc. Principal Investigator
Collaboration Network
Top Collaborators
- The molecular classification of multiple myeloma
- A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1
- Thalidomide and Hematopoietic-Cell Transplantation for Multiple Myeloma
- Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells
- Graft-versus-myeloma effect: proof of principle
Showing 5 of 72 shared publications
- The molecular classification of multiple myeloma
- A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1
- Thalidomide and Hematopoietic-Cell Transplantation for Multiple Myeloma
- Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells
- Extended survival in advanced and refractory multiple myeloma after single-agent thalidomide: identification of prognostic factors in a phase 2 study of 169 patients
Showing 5 of 67 shared publications
- The molecular classification of multiple myeloma
- A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1
- Thalidomide and Hematopoietic-Cell Transplantation for Multiple Myeloma
- Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells
- Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation
Showing 5 of 53 shared publications
- The molecular classification of multiple myeloma
- A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1
- Thalidomide and Hematopoietic-Cell Transplantation for Multiple Myeloma
- Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells
- Extended survival in advanced and refractory multiple myeloma after single-agent thalidomide: identification of prognostic factors in a phase 2 study of 169 patients
Showing 5 of 41 shared publications
- Thalidomide and Hematopoietic-Cell Transplantation for Multiple Myeloma
- Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells
- Results of autologous stem cell transplant in multiple myeloma patients with renal failure
- Age Is Not a Prognostic Variable With Autotransplants for Multiple Myeloma
- Autologous stem cell transplantation in elderly multiple myeloma patients over the age of 70 years
Showing 5 of 27 shared publications
- The molecular classification of multiple myeloma
- A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1
- Thalidomide and Hematopoietic-Cell Transplantation for Multiple Myeloma
- Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells
- Extended survival in advanced and refractory multiple myeloma after single-agent thalidomide: identification of prognostic factors in a phase 2 study of 169 patients
Showing 5 of 27 shared publications
- Geographic and Racial Disparities in Access to Chimeric Antigen Receptor–T Cells and Bispecific Antibodies Trials for Multiple Myeloma
- Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
- Clinical implications of loss of bone marrow minimal residual disease negativity in multiple myeloma
- Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages
- CST6 suppresses osteolytic bone disease in multiple myeloma by blocking osteoclast differentiation
Showing 5 of 26 shared publications
- Geographic and Racial Disparities in Access to Chimeric Antigen Receptor–T Cells and Bispecific Antibodies Trials for Multiple Myeloma
- Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
- Clinical implications of loss of bone marrow minimal residual disease negativity in multiple myeloma
- Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages
- CST6 suppresses osteolytic bone disease in multiple myeloma by blocking osteoclast differentiation
Showing 5 of 26 shared publications
- The molecular classification of multiple myeloma
- A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1
- Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation
- Magnetic Resonance Imaging in Multiple Myeloma: Diagnostic and Clinical Implications
- Unique role of cytogenetics in the prognosis of patients with myeloma receiving high-dose therapy and autotransplants.
Showing 5 of 21 shared publications
- The molecular classification of multiple myeloma
- A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1
- Thalidomide and Hematopoietic-Cell Transplantation for Multiple Myeloma
- Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells
- Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation
Showing 5 of 20 shared publications
- The molecular classification of multiple myeloma
- A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1
- Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells
- Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation
- Gene-expression signature of benign monoclonal gammopathy evident in multiple myeloma is linked to good prognosis
Showing 5 of 20 shared publications
- Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
- Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages
- High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
- Salvage Autologous Stem Cell Transplantation in Daratumumab-Refractory Multiple Myeloma
- Feasibility of Outpatient Stem Cell Transplantation in Multiple Myeloma and Risk Factors Predictive of Hospital Admission
Showing 5 of 19 shared publications
- Geographic and Racial Disparities in Access to Chimeric Antigen Receptor–T Cells and Bispecific Antibodies Trials for Multiple Myeloma
- Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
- Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages
- High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
- Feasibility of Outpatient Stem Cell Transplantation in Multiple Myeloma and Risk Factors Predictive of Hospital Admission
Showing 5 of 19 shared publications
- Poor prognosis in multiple myeloma is associated only with partial or complete deletions of chromosome 13 or abnormalities involving 11q and not with other karyotype abnormalities
- Unique role of cytogenetics in the prognosis of patients with myeloma receiving high-dose therapy and autotransplants.
- Long‐term outcome results of the first tandem autotransplant trial for multiple myeloma
- Preceding standard therapy is the likely cause of MDS after autotransplants for multiple myeloma
- Comparable engraftment kinetics following peripheral-blood stem-cell infusion mobilized with granulocyte colony-stimulating factor with or without cyclophosphamide in multiple myeloma.
Showing 5 of 18 shared publications
- Graft-versus-myeloma effect: proof of principle
- Extended survival in advanced and refractory multiple myeloma after single-agent thalidomide: identification of prognostic factors in a phase 2 study of 169 patients
- Results of autologous stem cell transplant in multiple myeloma patients with renal failure
- Age Is Not a Prognostic Variable With Autotransplants for Multiple Myeloma
- Autologous stem cell transplantation in elderly multiple myeloma patients over the age of 70 years
Showing 5 of 18 shared publications
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