Irosha N. Nawarathne Data-verified
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Professor and Director of Undergraduate Research
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Biography and Research Information
OverviewAI-generated summary
Irosha N. Nawarathne's research focuses on chemical synthesis and biocatalysis, particularly in the modification of natural products. Recent work includes the regioselective exchange of benzoyl groups on paclitaxel precursors, aiming to create next-generation paclitaxel drugs. This involves studying the kinetics and substrate specificity of enzymes, as demonstrated by work with *Escherichia coli* and acyltransferases. Nawarathne has also investigated methods for analyzing fatty acid compositions in rice bran oil and explored techniques for generating single-stranded DNA circles. Collaborations include work with researchers from the University of Arkansas at Fayetteville, Arkansas State University, and the University of Arkansas for Medical Sciences. Nawarathne holds a h-index of 6 with 11 total publications and 123 citations.
Metrics
- h-index: 6
- Publications: 11
- Citations: 123
Selected Publications
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Late-Stage Functionalization of the Rifamycin Core via Click Chemistry Toward New Antibacterial Derivatives (2026)
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Cover Feature: Biocatalytic and Regioselective Exchange of 2‐<i>O</i>‐Benzoyl for 2‐<i>O</i>‐(<i>m</i>‐Substituted)Benzoyl Groups to Make Precursors of Next‐Generation Paclitaxel Drugs (ChemCatChem 9/2024) (2024)
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Biocatalytic and Regioselective Exchange of 2‐<i>O</i>‐Benzoyl for 2‐<i>O</i>‐(<i>m</i>‐Substituted)Benzoyl Groups to Make Precursors of Next‐Generation Paclitaxel Drugs (2024)
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Correction to “Alkenes, Brought to You in Familiar Faces” (2022)
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Alkenes, Brought to You in Familiar Faces (2022)
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Facile analysis of rice bran oil to compare free unsaturated fatty acid compositions of parental and hybrid rice lines (2022)
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Generating single-stranded DNA circles with minimal resources (2021)
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