Josh Sakon
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Professor
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Josh Sakon's research focuses on understanding the molecular mechanisms underlying biological processes, particularly in protein structure and function. He has received federal funding from the NIH/National Institute of General Medical Sciences for his work on "Understanding Mechanisms of Antibiotic Inhibition of Ribosomal Subunit Joining," a project for which he serves as Principal Investigator, totaling $403,423. His scholarly output includes investigations into the structures of various enzymes, such as endo/exocellulase E4 and thermostable family 5 endocellulase E1, and their roles in cellulose hydrolysis. Sakon has also studied collagen-binding domains and the thermostability of proteins like staphylococcal nuclease. His recent work includes optimizing the production of cellulose nanocrystals and nanofibers from pine kraft pulp. He leads a research group and has established collaborations with researchers at the University of Arkansas at Pine Bluff and within the University of Arkansas at Fayetteville, including Rabindra Basnet, Dinesh Upreti, Md Rafique Un Nabi, and Gokul Acharya, with whom he has co-authored multiple publications.
Metrics
- h-index: 5
- Publications: 8
- Citations: 73
Positions
-
Professor 2016–presentUniversity of Arkansas Department of Chemistry and Biochemistry ORCID
-
Visiting Professor 2023–2024Okayama University Medical, Dental and Pharmaceutical Sciences ORCID
Selected Publications
-
Thermodynamics of Binding Between Adeno-Associated Viruses and Heparin in Bulk and at Interfaces via Isothermal Titration Calorimetry (2026)
-
Crystal structures of Escherichia coli glucokinase acetylation-mimicking variants and insights into the impact of acetylation (2026)
-
Bacterial collagenase harnesses collagen geometry for processive cleavage (2026)
-
Crystal structures of Escherichia coli glucokinase and insights into phosphate binding (2025)
-
Quantum oscillation studies of the nodal line semimetal Ni3In2S2-Se (2025)
-
Tuning magnetism in Ising-type van der Waals magnet FePS3 by lithium intercalation (2025)
-
Large negative magnetoresistance in the off-stoichiometric topological semimetal PrSb x Te 2 − x (2025)
-
Large negative magnetoresistance in antiferromagnetic G d 2 S e 3 (2025)
-
Medium‐Entropy Engineering of Magnetism in Layered Antiferromagnet CuxNi2(1‐x)CrxP2S6 (2024)
-
Evolution of magnetism in the magnetic topological semimetal NdS b x T e 2 − x + δ (2024)
-
Field-induced spin polarization in the lightly Cr-substituted layered antiferromagnet NiPS3 (2024)
-
Understanding and Tuning Magnetism in Layered Ising‐Type Antiferromagnet FePSe3 for Potential 2D Magnet (2024)
-
Crystal Growth and Electronic Properties of LaSbSe (2022)
-
Covalent Crosslinking of Colloidal Cellulose Nanocrystals for Multifunctional Nanostructured Hydrogels with Tunable Physicochemical Properties (2022)
-
Impact of species-based wood feedstock variability on physicochemical properties of cellulose nanocrystals (2022)
Federal Grants 1 $403,423 total
Understanding Mechanisms of Antibiotic Inhibition of Ribosomal Subunit Joining
Collaboration Network
Top Collaborators
- A bacterial collagen‐binding domain with novel calcium‐binding motif controls domain orientation
- Structural Comparison of ColH and ColG Collagen-Binding Domains from Clostridium histolyticum
- Unidirectional Binding of Clostridial Collagenase to Triple Helical Substrates
- Monthly Administration of a Novel PTH-Collagen Binding Domain Fusion Protein is Anabolic in Mice
- Bacterial collagen‐binding domain targets undertwisted regions of collagen
Showing 5 of 20 shared publications
- Treating osteoporosis by targeting parathyroid hormone to bone
- Monthly Administration of a Novel PTH-Collagen Binding Domain Fusion Protein is Anabolic in Mice
- Treatment for chemotherapy‐induced alopecia in mice using parathyroid hormone agonists and antagonists linked to a collagen binding domain
- Treatment and prevention of chemotherapy-induced alopecia with PTH-CBD, a collagen-targeted parathyroid hormone analog, in a non-depilated mouse model
- A Single Injection of the Anabolic Bone Agent, Parathyroid Hormone–Collagen Binding Domain (PTH–CBD), Results in Sustained Increases in Bone Mineral Density for up to 12 Months in Normal Female Mice
Showing 5 of 11 shared publications
- Treating osteoporosis by targeting parathyroid hormone to bone
- Monthly Administration of a Novel PTH-Collagen Binding Domain Fusion Protein is Anabolic in Mice
- Treatment for chemotherapy‐induced alopecia in mice using parathyroid hormone agonists and antagonists linked to a collagen binding domain
- Treatment and prevention of chemotherapy-induced alopecia with PTH-CBD, a collagen-targeted parathyroid hormone analog, in a non-depilated mouse model
- A Single Injection of the Anabolic Bone Agent, Parathyroid Hormone–Collagen Binding Domain (PTH–CBD), Results in Sustained Increases in Bone Mineral Density for up to 12 Months in Normal Female Mice
Showing 5 of 10 shared publications
- Treating osteoporosis by targeting parathyroid hormone to bone
- Monthly Administration of a Novel PTH-Collagen Binding Domain Fusion Protein is Anabolic in Mice
- Treatment for chemotherapy‐induced alopecia in mice using parathyroid hormone agonists and antagonists linked to a collagen binding domain
- Treatment and prevention of chemotherapy-induced alopecia with PTH-CBD, a collagen-targeted parathyroid hormone analog, in a non-depilated mouse model
- A Single Injection of the Anabolic Bone Agent, Parathyroid Hormone–Collagen Binding Domain (PTH–CBD), Results in Sustained Increases in Bone Mineral Density for up to 12 Months in Normal Female Mice
Showing 5 of 10 shared publications
- Maximizing production of cellulose nanocrystals and nanofibers from pre-extracted loblolly pine kraft pulp: a response surface approach
- Investigating the effects of hemicellulose pre-extraction on the production and characterization of loblolly pine nanocellulose
- Covalent Crosslinking of Colloidal Cellulose Nanocrystals for Multifunctional Nanostructured Hydrogels with Tunable Physicochemical Properties
- Impact of species-based wood feedstock variability on physicochemical properties of cellulose nanocrystals
- Aqueous-phase synthesis of monodisperse plasmonic gold nanocrystals using shortened single-walled carbon nanotubes
Showing 5 of 8 shared publications
- Understanding and Tuning Magnetism in Layered Ising‐Type Antiferromagnet FePSe3 for Potential 2D Magnet
- Evolution of magnetism in the magnetic topological semimetal NdS b x T e 2 − x + δ
- Crystal Growth and Electronic Properties of LaSbSe
- Large negative magnetoresistance in antiferromagnetic G d 2 S e 3
- Field-induced spin polarization in the lightly Cr-substituted layered antiferromagnet NiPS3
Showing 5 of 8 shared publications
- Understanding and Tuning Magnetism in Layered Ising‐Type Antiferromagnet FePSe3 for Potential 2D Magnet
- Evolution of magnetism in the magnetic topological semimetal NdS b x T e 2 − x + δ
- Crystal Growth and Electronic Properties of LaSbSe
- Large negative magnetoresistance in antiferromagnetic G d 2 S e 3
- Field-induced spin polarization in the lightly Cr-substituted layered antiferromagnet NiPS3
Showing 5 of 8 shared publications
- Understanding and Tuning Magnetism in Layered Ising‐Type Antiferromagnet FePSe3 for Potential 2D Magnet
- Evolution of magnetism in the magnetic topological semimetal NdS b x T e 2 − x + δ
- Large negative magnetoresistance in antiferromagnetic G d 2 S e 3
- Field-induced spin polarization in the lightly Cr-substituted layered antiferromagnet NiPS3
- Medium‐Entropy Engineering of Magnetism in Layered Antiferromagnet CuxNi2(1‐x)CrxP2S6
Showing 5 of 8 shared publications
- Understanding and Tuning Magnetism in Layered Ising‐Type Antiferromagnet FePSe3 for Potential 2D Magnet
- Evolution of magnetism in the magnetic topological semimetal NdS b x T e 2 − x + δ
- Large negative magnetoresistance in antiferromagnetic G d 2 S e 3
- Field-induced spin polarization in the lightly Cr-substituted layered antiferromagnet NiPS3
- Medium‐Entropy Engineering of Magnetism in Layered Antiferromagnet CuxNi2(1‐x)CrxP2S6
Showing 5 of 8 shared publications
- Understanding and Tuning Magnetism in Layered Ising‐Type Antiferromagnet FePSe3 for Potential 2D Magnet
- Evolution of magnetism in the magnetic topological semimetal NdS b x T e 2 − x + δ
- Large negative magnetoresistance in antiferromagnetic G d 2 S e 3
- Field-induced spin polarization in the lightly Cr-substituted layered antiferromagnet NiPS3
- Medium‐Entropy Engineering of Magnetism in Layered Antiferromagnet CuxNi2(1‐x)CrxP2S6
Showing 5 of 8 shared publications
- Understanding and Tuning Magnetism in Layered Ising‐Type Antiferromagnet FePSe3 for Potential 2D Magnet
- Evolution of magnetism in the magnetic topological semimetal NdS b x T e 2 − x + δ
- Large negative magnetoresistance in antiferromagnetic G d 2 S e 3
- Field-induced spin polarization in the lightly Cr-substituted layered antiferromagnet NiPS3
- Medium‐Entropy Engineering of Magnetism in Layered Antiferromagnet CuxNi2(1‐x)CrxP2S6
Showing 5 of 8 shared publications
- Structural Comparison of ColH and ColG Collagen-Binding Domains from Clostridium histolyticum
- Unidirectional Binding of Clostridial Collagenase to Triple Helical Substrates
- Bacterial collagen‐binding domain targets undertwisted regions of collagen
- Ca2+‐induced linker transformation leads to a compact and rigid collagen‐binding domain of Clostridium histolyticum collagenase
- Probing the 3-D Structure, Dynamics, and Stability of Bacterial Collagenase Collagen Binding Domain (apo- versus holo-) by Limited Proteolysis MALDI-TOF MS
Showing 5 of 6 shared publications
- Large negative magnetoresistance in antiferromagnetic G d 2 S e 3
- Field-induced spin polarization in the lightly Cr-substituted layered antiferromagnet NiPS3
- Medium‐Entropy Engineering of Magnetism in Layered Antiferromagnet CuxNi2(1‐x)CrxP2S6
- Quantum oscillation studies of the nodal line semimetal Ni3In2S2-Se
- Large negative magnetoresistance in the off-stoichiometric topological semimetal PrSb x Te 2 − x
Showing 5 of 6 shared publications
- Structural Comparison of ColH and ColG Collagen-Binding Domains from Clostridium histolyticum
- Structures of three polycystic kidney disease-like domains fromClostridium histolyticumcollagenases ColG and ColH
- Ca2+‐induced orientation of tandem collagen binding domains from clostridial collagenase ColG permits two opposing functions of collagen fibril formation and retardation
- The Crystal Structure of the Polycystic Kidney Disease Domain (PKD) from Clostridium Histolyticum Collagenase: Insight into the Role of the PKD in Collagenase
- Activation and binding mechanisms of the tandem collagen‐binding domain of ColG collagenase
- Maximizing production of cellulose nanocrystals and nanofibers from pre-extracted loblolly pine kraft pulp: a response surface approach
- Investigating the effects of hemicellulose pre-extraction on the production and characterization of loblolly pine nanocellulose
- Covalent Crosslinking of Colloidal Cellulose Nanocrystals for Multifunctional Nanostructured Hydrogels with Tunable Physicochemical Properties
- Impact of species-based wood feedstock variability on physicochemical properties of cellulose nanocrystals
- Enhanced Localized Surface Plasmon Resonance of Gold Nanoparticles Synthesized on Cellulose Nanocrystals
Similar Researchers
Based on overlapping research topics