Match tier
Confirmed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-08
K
Kyle P. Quinn
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Federal Grant PI
High Impact
Professor
Also affiliated: Tufts University (2011–2026); Brigham and Women's Hospital (2014); Harvard University (2014); University of Pennsylvania (2006–2011)
36 h-index
174 pubs
4,448 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Kyle P. Quinn's research focuses on developing and applying advanced optical imaging techniques to investigate biological processes, particularly in the context of metabolism, aging, and wound healing. He has received significant federal funding, including over $726,000 from the NIH to investigate automated wound analysis using deep learning and to characterize aged skin for predicting delayed wound healing. An additional NSF grant of $50,000 supported work on a skin autofluorescence imager for assessing wound healing.
His work utilizes endogenous fluorescence, such as NAD(P)H and FAD, to non-invasively map metabolic changes in tissues. Publications demonstrate applications in areas including precancerous epithelial tissues, stem cell differentiation, and cardiac extracellular matrix. Quinn has also been involved in research exploring how the extracellular matrix influences stem cell therapeutic potential following myocardial infarction and how skin aging impacts wound healing responses.
Quinn holds a high-impact researcher designation, evidenced by an h-index of 36 and over 4,400 citations across 176 publications. He collaborates with several researchers at the University of Arkansas at Fayetteville, including Alan E. Woessner, with whom he shares 16 publications. He also holds a Co-PI role on an NSF REU grant focused on training in biomedical optics and imaging.
Metrics
- h-index: 36
- Publications: 174
- Citations: 4,448
Positions
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Professor 2025–presentTufts University Biomedical Engineering ORCID
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Professor 2023–presentUniversity of Arkansas Department of Biomedical Engineering ORCID
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Assistant Professor 2015–presentUniversity of Arkansas Fayetteville Biomedical Engineering ORCID
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Postdoctoral Fellow 2010–2015Tufts University Biomedical Engineering ORCID
Selected Publications
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Force-responsive biomaterials drive tissue repair by harnessing endogenous growth factors (2026)
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NADH FLIM reveals cellular bioenergetics and mitochondrial morphology during Drosophila convergent extension (2026)
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Autofluorescence lifetime of gelatin-methacrylate hydrogels is sensitive to changes in crosslinking and post-gelation pH (2026)
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Optical metabolic imaging of tumor recurrence in non-small cell lung cancer (2026)
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In Vivo , Label-Free Multiphoton Microscopy Is Sensitive to Altered Metabolism and Structure in Aged Skin (2026)
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Metabolic Imaging and Characterization of Multicomponent Spheroid Models in Vitro. (2025)
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Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling (2025)
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Understanding Skin Wound Healing Dynamics Through AI-Powered Analysis of Label-free Multiphoton Imaging (2025)
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Optical imaging of treatment-naïve human NSCLC reveals changes associated with metastatic recurrence (2024)
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A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression (2024)
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Identifying and training deep learning neural networks on biomedical-related datasets (2024)
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Quantifying the Interaction between Age and Diabetes on Skin Wound Metabolism Using In Vivo Multiphoton Microscopy (2024)
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Quantification of age-related changes in the structure and mechanical function of skin with multiscale imaging (2024)
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Pre-Incisional and Multiple Intradermal Injection of N-Acetylcysteine Slightly Improves Incisional Wound Healing in an Animal Model (2024)
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CapsNet for medical image segmentation (2024)
Federal Grants 4 $1,190,838 total
NIH
Contact PI
Aug 2021 - Apr 2026
Non-invasive automated wound analysis via deep learning neural networks
NIH
Contact PI
Sep 2017 - May 2023
In vivo label-free characterization of aged skin to predict delayed wound healing
NSF
PI
Dec 2023 - Nov 2025
I-Corps: Skin autofluorescence imager for rapidly assessing skin wound healing
NSF
Co-PI
May 2023 - Apr 2027
REU Site: Training in Emerging Biomedical Optics and Imaging Approaches
Collaboration Network
Top Collaborators
Alan E. Woessner
University of Arkansas at Fayetteville
28 shared publications
In database
- Skin Structure–Function Relationships and the Wound Healing Response to Intrinsic Aging
- In vivo multiphoton microscopy detects longitudinal metabolic changes associated with delayed skin wound healing
- Quantifying Age-Related Changes in Skin Wound Metabolism Using In Vivo Multiphoton Microscopy
- Characterizing differences in the collagen fiber organization of skin wounds using quantitative polarized light imaging
- Three-Dimensional Quantification of Collagen Microstructure During Tensile Mechanical Loading of Skin
Showing 5 of 28 shared publications
Jake D. Jones
University of Arkansas at Fayetteville
20 shared publications
In database
- Skin Structure–Function Relationships and the Wound Healing Response to Intrinsic Aging
- In vivo multiphoton microscopy detects longitudinal metabolic changes associated with delayed skin wound healing
- Quantifying Age-Related Changes in Skin Wound Metabolism Using In Vivo Multiphoton Microscopy
- Characterizing differences in the collagen fiber organization of skin wounds using quantitative polarized light imaging
- Three-Dimensional Quantification of Collagen Microstructure During Tensile Mechanical Loading of Skin
Showing 5 of 20 shared publications
Irene Georgakoudi
Dartmouth College (US)
14 shared publications
- Mapping metabolic changes by noninvasive, multiparametric, high-resolution imaging using endogenous contrast
- Imaging mitochondrial dynamics in human skin reveals depth-dependent hypoxia and malignant potential for diagnosis
- Label-Free Optical Metabolic Imaging in Cells and Tissues
- Automated quantification of three-dimensional organization of fiber-like structures in biological tissues
- Optical metrics of the extracellular matrix predict compositional and mechanical changes after myocardial infarction
Showing 5 of 14 shared publications
Narasimhan Rajaram
University of Arkansas at Fayetteville
10 shared publications
In database
- Optical redox ratio identifies metastatic potential-dependent changes in breast cancer cell metabolism
- Valve interstitial cell contractile strength and metabolic state are dependent on its shape
- Optical imaging of radiation-induced metabolic changes in radiation-sensitive and resistant cancer cells
- A Radiosensitizing Inhibitor of HIF-1 alters the Optical Redox State of Human Lung Cancer Cells In Vitro
- Rapid quantification of mitochondrial fractal dimension in individual cells
Showing 5 of 10 shared publications
Marcos R. Rodriguez
Tufts University
9 shared publications
In database
- Automated Extraction of Skin Wound Healing Biomarkers From In Vivo Label‐Free Multiphoton Microscopy Using Convolutional Neural Networks
- Autofluorescence lifetime of gelatin-methacrylate hydrogels is sensitive to changes in cross-linking and pH
- In Vivo , Label-Free Multiphoton Microscopy Is Sensitive to Altered Metabolism and Structure in Aged Skin
- Multimodal characterization of skin wound healing in vivo using label-free multiphoton microscopy
- Quantifying Age-Related Changes in Skin Microstructure and Function Using In Vivo Multiphoton Microscopy
Showing 5 of 9 shared publications
Zhiyi Liu
Dartmouth Institute for Health Policy and Clinical Practice (US)
8 shared publications
- Mapping metabolic changes by noninvasive, multiparametric, high-resolution imaging using endogenous contrast
- Imaging mitochondrial dynamics in human skin reveals depth-dependent hypoxia and malignant potential for diagnosis
- Optical metrics of the extracellular matrix predict compositional and mechanical changes after myocardial infarction
- Non-destructive two-photon excited fluorescence imaging identifies early nodules in calcific aortic-valve disease
- 3D organizational mapping of collagen fibers elucidates matrix remodeling in a hormone-sensitive 3D breast tissue model
Showing 5 of 8 shared publications
Edward A. Sander
University of Iowa (US)
8 shared publications
- Three-Dimensional Quantification of Collagen Microstructure During Tensile Mechanical Loading of Skin
- Quantification of age-related changes in the structure and mechanical function of skin with multiscale imaging
- Mechanical Models of Collagen Networks for Understanding Changes in the Failure Properties of Aging Skin
- Multiscale Computational Model Predicts Mouse Skin Kinematics Under Tensile Loading
- Quantifying age-related changes in the structure and mechanical function of skin with multiscale imaging
Showing 5 of 8 shared publications
Timothy J. Muldoon
University of Arkansas at Fayetteville
6 shared publications
In database
- Optical redox ratio identifies metastatic potential-dependent changes in breast cancer cell metabolism
- Valve interstitial cell contractile strength and metabolic state are dependent on its shape
- Differences in colonic crypt morphology of spontaneous and colitis-associated murine models via second harmonic generation imaging to quantify colon cancer development
- Label-free optical biomarkers detect early calcific aortic valve disease in a wild-type mouse model
- Optical spectroscopic and imaging biomarkers of ulcerative colitis disease progression and remission (Conference Presentation)
Showing 5 of 6 shared publications
Kartik Balachandran
University of Arkansas at Fayetteville
6 shared publications
In database
- Valve interstitial cell contractile strength and metabolic state are dependent on its shape
- Label-free metabolic biomarkers for assessing valve interstitial cell calcific progression
- Label-Free Multiphoton Microscopy for the Detection and Monitoring of Calcific Aortic Valve Disease
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
- Label-free optical biomarkers detect early calcific aortic valve disease in a wild-type mouse model
Showing 5 of 6 shared publications
Dimitra Pouli
Tufts University (US)
6 shared publications
- Mapping metabolic changes by noninvasive, multiparametric, high-resolution imaging using endogenous contrast
- Imaging mitochondrial dynamics in human skin reveals depth-dependent hypoxia and malignant potential for diagnosis
- Automated quantification of three-dimensional organization of fiber-like structures in biological tissues
- Endogenous Two-Photon Excited Fluorescence Imaging Characterizes Neuron and Astrocyte Metabolic Responses to Manganese Toxicity
- 3D organizational mapping of collagen fibers elucidates matrix remodeling in a hormone-sensitive 3D breast tissue model
Showing 5 of 6 shared publications
Carlo Alonzo
Tufts University (US)
6 shared publications
- Mapping metabolic changes by noninvasive, multiparametric, high-resolution imaging using endogenous contrast
- Imaging mitochondrial dynamics in human skin reveals depth-dependent hypoxia and malignant potential for diagnosis
- Automated quantification of three-dimensional organization of fiber-like structures in biological tissues
- Endogenous Two-Photon Excited Fluorescence Imaging Characterizes Neuron and Astrocyte Metabolic Responses to Manganese Toxicity
- 3D organizational mapping of collagen fibers elucidates matrix remodeling in a hormone-sensitive 3D breast tissue model
Showing 5 of 6 shared publications
Hallie E. Ramser
University of Arkansas at Fayetteville
6 shared publications
In database
- In vivo multiphoton microscopy detects longitudinal metabolic changes associated with delayed skin wound healing
- Quantifying Age-Related Changes in Skin Wound Metabolism Using In Vivo Multiphoton Microscopy
- Efficacy of Combined in-vivo Electroporation-Mediated Gene Transfer of VEGF, HGF, and IL-10 on Skin Flap Survival, Monitored by Label-Free Optical Imaging: A Feasibility Study
- Non-invasive in vivo characterization of skin wound healing using label-free multiphoton microscopy (Conference Presentation)
- Longitudinal Monitoring of Skin Wounds In Vivo Using Label-free Multiphoton Microscopy
Showing 5 of 6 shared publications
Olivia I. Kolenc
University of Arkansas at Fayetteville
6 shared publications
In database
- Evaluating Cell Metabolism Through Autofluorescence Imaging of NAD(P)H and FAD
- Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle
- Label-free metabolic biomarkers for assessing valve interstitial cell calcific progression
- Rapid quantification of mitochondrial fractal dimension in individual cells
- Creating patient-specific stem cell models and characterizing metabolic changes in Leigh’s Syndrome
Showing 5 of 6 shared publications
Nathan J. Witt
University of Iowa (US)
6 shared publications
- Three-Dimensional Quantification of Collagen Microstructure During Tensile Mechanical Loading of Skin
- Quantification of age-related changes in the structure and mechanical function of skin with multiscale imaging
- Mechanical Models of Collagen Networks for Understanding Changes in the Failure Properties of Aging Skin
- Multiscale Computational Model Predicts Mouse Skin Kinematics Under Tensile Loading
- Quantifying age-related changes in the structure and mechanical function of skin with multiscale imaging
Showing 5 of 6 shared publications
Kinan Alhallak
University of Arkansas at Fayetteville (US)
5 shared publications
- Optical redox ratio identifies metastatic potential-dependent changes in breast cancer cell metabolism
- Optical imaging of radiation-induced metabolic changes in radiation-sensitive and resistant cancer cells
- A Radiosensitizing Inhibitor of HIF-1 alters the Optical Redox State of Human Lung Cancer Cells In Vitro
- Rapid quantification of mitochondrial fractal dimension in individual cells
- Optical Metabolic Imaging of TWIST Inhibition in 4T1 Breast Cancer Cells
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