L
Lei Guo Data-verified
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
High Impact
Assistant Professor
faculty
45 h-index
488 pubs
5,993 cited
Research Areas
Biography and Research Information
OverviewAI-generated summary
Lei Guo is an Assistant Professor at the University of Arkansas at Fayetteville. Guo's research program focuses on the development and application of advanced sensing platforms for the detection of biomarkers and environmental contaminants. This work has led to the creation of novel electrochemical and electrochemiluminescence immunosensors and aptasensors for the sensitive detection of non-small cell lung cancer (NSCLC) biomarkers and antigens, as well as metal ions like Fe3+ and Fe2+.
Further research extends to environmental applications, including the design of functionalized materials for wastewater purification. Guo has investigated materials such as Zr-MOF functionalized nanochannels and biomimetic ZrO2-modified seaweed residue for applications in fluorine and bacteria removal, and uranium extraction. The lab also explores the functionalization of cellulose-based materials for environmental remediation and sustainability.
Guo's work utilizes techniques such as tandem mass spectrometry and nanomaterials, including metal nanoparticles and metal-organic frameworks (MOFs). The group also investigates exosomes derived from pretreated mesenchymal stem cells for their role in promoting angiogenesis and facilitating diabetic wound healing. Guo has a publication record of 488 papers with 3,907 citations and an h-index of 35, and is recognized as a highly cited researcher.
Metrics
- h-index: 45
- Publications: 488
- Citations: 5,993
Selected Publications
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Fluorous Modification of Commercial Resins for Ultrashort and Short Chain PFAS Removal (2025)
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Inhibition of Urea Hydrolysis in Human Urine for Resource and Energy Recovery: Pharmaceuticals and Their Metabolites as Co-Existing Anticatalyzers (2025)
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Fluorous Modification of Commercial Resins for Ultrashort and Short Chain PFAS Removal (2025)
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Harnessing Fluorine Chemistry: Strategies for Per‐ and Polyfluoroalkyl Substances Removal and Enrichment (2025)
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A Metal-Organic Framework Decorated Filter For Fractionation and Isolation of Proteins Using Uio-66-Nh2 (2025)
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Engineering Central Substitutions in Heptamethine Dyes for Improved Fluorophore Performance (2024)
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Engineering Central Substitutions in Heptamethine Dyes via Aryl-lithium Addition for Improved Fluorophore Performance (2024)
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Water-soluble chromenylium dyes for shortwave infrared imaging in mice (2023)
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Modular Functionalization of Metal‐Organic Frameworks for Nitrogen Recovery from Fresh Urine** (2023)
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Modular Functionalization of Metal‐Organic Frameworks for Nitrogen Recovery from Fresh Urine** (2023)
Collaboration Network
Top Collaborators
Jianwei Xie
Academy of Military Medical Sciences (CN)
23 shared publications
- Label-free differentiation and quantification of ricin, abrin from their agglutinin biotoxins by surface plasmon resonance
- A novel approach for on-site screening of organophosphorus nerve agents based on DTNB modified AgNPs using surface-enhanced Raman spectrometry
- Thermal desorption bridged the gap between dielectric barrier discharge ionization and dried plasma spot samples for sensitive and rapid detection of fentanyl analogs in mass spectrometry
- Rapid detection of whole active ricin using a surface‐enhanced Raman scattering‐based sandwich immunoassay
- Structural annotation, semi-quantification and toxicity prediction of pyrrolizidine alkaloids from functional food: In silico and molecular networking strategy
Showing 5 of 23 shared publications
Hua Xu
Academy of Military Medical Sciences (CN)
9 shared publications
- Label-free differentiation and quantification of ricin, abrin from their agglutinin biotoxins by surface plasmon resonance
- Rapid detection of whole active ricin using a surface‐enhanced Raman scattering‐based sandwich immunoassay
- Differential comparison of genotoxic effects of aristolochic acid I and II in human cells by the mass spectroscopic quantification of γ-H2AX
- Dynamically monitoring cellular γ-H2AX reveals the potential of carcinogenicity evaluation for genotoxic compounds
- Double amplification upon immuno-gold nanoparticles promoted trace measurement of ricin by biolayer interferometry
Showing 5 of 9 shared publications
Li Luo
Academy of Military Medical Sciences (CN)
6 shared publications
- Label-free differentiation and quantification of ricin, abrin from their agglutinin biotoxins by surface plasmon resonance
- Rapid detection of whole active ricin using a surface‐enhanced Raman scattering‐based sandwich immunoassay
- Highly sensitive MALDI-MS measurement of active ricin: insight from more potential deoxynucleobase-hybrid oligonucleotide substrates
- Double amplification upon immuno-gold nanoparticles promoted trace measurement of ricin by biolayer interferometry
- A Glycoprotein-Based Surface-Enhanced Raman Spectroscopy–Lateral Flow Assay Method for Abrin and Ricin Detection
Showing 5 of 6 shared publications
Jianfeng Wu
Academy of Military Medical Sciences (CN)
5 shared publications
- A novel approach for on-site screening of organophosphorus nerve agents based on DTNB modified AgNPs using surface-enhanced Raman spectrometry
- Rapid detection of whole active ricin using a surface‐enhanced Raman scattering‐based sandwich immunoassay
- Structural annotation, semi-quantification and toxicity prediction of pyrrolizidine alkaloids from functional food: In silico and molecular networking strategy
- Quantification and toxicokinetics of paraquat in mouse plasma and lung tissues by internal standard surface-enhanced Raman spectroscopy
- In Vitro Evaluation of DNA Damage Effect Markers toward Five Nitrogen Mustards Based on Liquid Chromatography–Tandem Mass Spectrometry
Bin Xu
Academy of Military Medical Sciences (CN)
4 shared publications
- Highly sensitive MALDI-MS measurement of active ricin: insight from more potential deoxynucleobase-hybrid oligonucleotide substrates
- Abundance of Modifications in Mature miRNAs Revealed by LC-MS/MS Method Coupled with a Two-Step Hybridization Purification Strategy
- Identification evidence unraveled by strict proteomics rules toward forensic samples
- Analysis and identification of suspected snake venom samples using nano-ultra-high performance liquid chromatography-high resolution mass spectrometry
Yanqin Liu
Academy of Military Medical Sciences (CN)
3 shared publications
- Molecular modeling-guided optimization of acetylcholinesterase reactivators: A proof for reactivation of covalently inhibited targets
- The reactivation kinetic analysis, molecular docking, and dynamics of oximes against three V-type nerve agents inhibited four human cholinesterases
- The kinetic and molecular docking analysis of interactions between three V-type nerve agents and four human cholinesterases
Minmin Qu
Academy of Military Medical Sciences (CN)
3 shared publications
- Differential comparison of genotoxic effects of aristolochic acid I and II in human cells by the mass spectroscopic quantification of γ-H2AX
- Dynamically monitoring cellular γ-H2AX reveals the potential of carcinogenicity evaluation for genotoxic compounds
- Abundance of Modifications in Mature miRNAs Revealed by LC-MS/MS Method Coupled with a Two-Step Hybridization Purification Strategy
Lili Wang
Academy of Military Medical Sciences (CN)
3 shared publications
- Label-free differentiation and quantification of ricin, abrin from their agglutinin biotoxins by surface plasmon resonance
- Sensitive Detection and Differentiation of Biologically Active Ricin and Abrin in Complex Matrices via Specific Neutralizing Antibody-Based Cytotoxicity Assay
- Neutralizing Monoclonal Antibody, mAb 10D8, Is an Effective Detoxicant against Abrin-a Both In Vitro and In Vivo
Zehua Li
Academy of Military Medical Sciences (CN)
3 shared publications
- Thermal desorption bridged the gap between dielectric barrier discharge ionization and dried plasma spot samples for sensitive and rapid detection of fentanyl analogs in mass spectrometry
- In Vitro Evaluation of DNA Damage Effect Markers toward Five Nitrogen Mustards Based on Liquid Chromatography–Tandem Mass Spectrometry
- Analysis and identification of suspected snake venom samples using nano-ultra-high performance liquid chromatography-high resolution mass spectrometry
Bo Ma
Academy of Military Medical Sciences (CN)
3 shared publications
- Differential comparison of genotoxic effects of aristolochic acid I and II in human cells by the mass spectroscopic quantification of γ-H2AX
- Sensitive Detection and Differentiation of Biologically Active Ricin and Abrin in Complex Matrices via Specific Neutralizing Antibody-Based Cytotoxicity Assay
- Neutralizing Monoclonal Antibody, mAb 10D8, Is an Effective Detoxicant against Abrin-a Both In Vitro and In Vivo
Jia Chen
Academy of Military Medical Sciences (CN)
3 shared publications
- Differential comparison of genotoxic effects of aristolochic acid I and II in human cells by the mass spectroscopic quantification of γ-H2AX
- Identification evidence unraveled by strict proteomics rules toward forensic samples
- Analysis and identification of suspected snake venom samples using nano-ultra-high performance liquid chromatography-high resolution mass spectrometry
Yulong Liu
Academy of Military Medical Sciences (CN)
3 shared publications
- A novel approach for on-site screening of organophosphorus nerve agents based on DTNB modified AgNPs using surface-enhanced Raman spectrometry
- The reactivation kinetic analysis, molecular docking, and dynamics of oximes against three V-type nerve agents inhibited four human cholinesterases
- The kinetic and molecular docking analysis of interactions between three V-type nerve agents and four human cholinesterases
Chuang Wang
Minzu University of China (CN)
3 shared publications
- SCX-tip-aided LC-MS detection of active ricin<i>via</i>oligonucleotide substrates for depurination kinetics
- Analysis and identification of suspected snake venom samples using nano-ultra-high performance liquid chromatography-high resolution mass spectrometry
- In Silico–Ex Vitro Iteration Strategy for Affinity Maturation of Anti-Ricin Peptides and the SPR Biosensing Application
Lan Xiao
Minzu University of China (CN)
3 shared publications
- A Glycoprotein-Based Surface-Enhanced Raman Spectroscopy–Lateral Flow Assay Method for Abrin and Ricin Detection
- SCX-tip-aided LC-MS detection of active ricin<i>via</i>oligonucleotide substrates for depurination kinetics
- In Silico–Ex Vitro Iteration Strategy for Affinity Maturation of Anti-Ricin Peptides and the SPR Biosensing Application
Yu Lei
Qingdao University (CN)
3 shared publications
- Biomimetic ZrO2-modified seaweed residue with excellent fluorine/ bacteria removal and uranium extraction properties for wastewater purification
- Functionalization of cellulose-based sponges: Design, modification, environmental applications, and sustainability analysis
- Functionalization of loofah sponge as a natural cellulose-based material for water environment remediation and sustainability assessment
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