Pascale Chavassieux
Researcher
Lyon College
faculty
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Biography and Research Information
OverviewAI-generated summary
Pascale Chavassieux's work focuses on bone health, osteoporosis, and related metabolic diseases. Her research encompasses the investigation of bone pathophysiology, with a particular emphasis on bone remodeling dynamics and the impact of various treatments. Chavassieux has explored the effects of bisphosphonates on bone formation, as well as the benefits of romosozumab treatment over different durations. Her work also includes phenotyping approaches in human, mice, and zebrafish models within the EU Cost Action GEMSTONE. A recent study involved the reconstruction of remodeling units to reveal positive effects after 2 and 12 months of romosozumab treatment. Chavassieux's investigations contribute to understanding bone metabolism and the effects of treatments for parathyroid disorders and bone and joint diseases.
Metrics
- h-index: 41
- Publications: 138
- Citations: 5,963
Selected Publications
- Denosumab treatment of osteoporotic women arrests cortical bone remodeling events at the reversal-resorption phase but does not affect ongoing bone formation (2025) DOI
- Rôle de l’adiposité médullaire dans le métabolisme osseux au cours du diabète de type 2 (2025) DOI
- Le rôle du diabète de type 2 (D2T) sur les caractéristiques du tissu osseux : l’étude DIABONE (2024) DOI
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