Weigong Ge
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Researcher
Also affiliated: United States Food and Drug Administration (2006–2025); Northern Kentucky University (2021); Central China Normal University (2021); Cancer Research And Biostatistics (2025); Food and Drug Administration (2010); ICF International (United States) (2008); Thermo Fisher Scientific (Norway) (2014)
Faculty Researcher
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Weigong Ge's research program focuses on the application of computational methods, including machine learning and deep learning, to address challenges in toxicology, drug discovery, and bioinformatics. His work has investigated the prediction of molecular properties relevant to drug safety, such as the blockade of the hERG channel, utilizing quantitative structure-activity relationship (QSAR) modeling. Ge has also explored the use of AI for analyzing large biomedical datasets, including the FAERS database for opioid-related adverse events and comparing topic modeling algorithms for risk assessment.
Further research by Ge includes the development of predictive models for drug repurposing, such as a random forest model for SARS-CoV-2 main protease binding. He has also contributed to understanding genetic variation by assessing the reproducibility of inherited variants detected through whole-genome sequencing. His collaborators at the National Center for Toxicological Research include Joe Meehan, Bohu Pan, Baitang Ning, and Wen Zou, with whom he has co-authored numerous publications.
Ge's scholarship is recognized by a high-impact researcher designation, supported by 72 publications and over 6,700 citations, with an h-index of 25. His recent work demonstrates a continued engagement with advanced computational techniques for biological and chemical data analysis, including the application of deep learning to nanomaterial properties and the use of natural language processing for health-related data.
Metrics
- h-index: 25
- Publications: 72
- Citations: 6,831
Selected Publications
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Developing predictive models for µ opioid receptor binding using machine learning and deep learning techniques (2025)
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AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women (2025)
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Machine learning and deep learning approaches for enhanced prediction of hERG blockade: a comprehensive QSAR modeling study (2024)
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A systematic analysis and data mining of opioid-related adverse events submitted to the FAERS database (2023)
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Developing a SARS-CoV-2 main protease binding prediction random forest model for drug repurposing for COVID-19 treatment (2023)
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Mold2 Descriptors Facilitate Development of Machine Learning and Deep Learning Models for Predicting Toxicity of Chemicals (2023)
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Additional file 3 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing (2022)
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Additional file 13 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing (2022)
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Additional file 5 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing (2022)
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Additional file 15 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing (2022)
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Additional file 10 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing (2022)
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Additional file 9 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing (2022)
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Additional file 11 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing (2022)
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Additional file 1 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing (2022)
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Additional file 6 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing (2022)
Collaboration Network
Top Collaborators
- Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Mold2 Descriptors Facilitate Development of Machine Learning and Deep Learning Models for Predicting Toxicity of Chemicals
- Additional file 14 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 2 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 4 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
Showing 5 of 16 shared publications
- Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 14 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 2 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 4 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 7 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
Showing 5 of 15 shared publications
- Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 14 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 2 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 4 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 7 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
Showing 5 of 15 shared publications
- Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 14 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 2 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 4 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 7 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
Showing 5 of 15 shared publications
- Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 14 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 2 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 4 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 7 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
Showing 5 of 15 shared publications
- Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 14 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 2 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 4 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 7 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
Showing 5 of 15 shared publications
- Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 14 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 2 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 4 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 7 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
Showing 5 of 15 shared publications
- Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 14 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 2 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 4 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 7 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
Showing 5 of 15 shared publications
- Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 14 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 2 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 4 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 7 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
Showing 5 of 15 shared publications
- Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 14 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 2 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 4 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 7 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
Showing 5 of 15 shared publications
- Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 14 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 2 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 4 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 7 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
Showing 5 of 15 shared publications
- Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 14 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 2 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 4 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 7 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
Showing 5 of 15 shared publications
- Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 14 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 2 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 4 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 7 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
Showing 5 of 15 shared publications
- Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 14 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 2 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 4 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 7 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
Showing 5 of 15 shared publications
- Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 14 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 2 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 4 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
- Additional file 7 of Assessing reproducibility of inherited variants detected with short-read whole genome sequencing
Showing 5 of 15 shared publications
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