Seong Wook Kang Source Confirmed

OverviewAI-generated summary

Seong Wook Kang's research focuses on immune response and inflammation, particularly in the context of inflammatory and autoimmune diseases such as rheumatoid arthritis and osteoarthritis. His work investigates the molecular mechanisms underlying these conditions, including the role of specific cellular pathways and signaling molecules.

Recent publications from Kang's laboratory have explored how cytoplasmic zinc influences IL-1β production in monocytes and macrophages through mTORC1 signaling in rheumatoid arthritis. Other studies have examined the effects of activated platelets on monocyte phenotypes and phagocytosis, as well as the induction of decoy receptors that block IL-1β-dependent responses in Th17 cells. His group has also investigated the impact of nanoparticles, such as p16INK4a-siRNA, on cartilage degeneration in osteoarthritis by inhibiting inflammation in fibroblast-like synoviocytes. Furthermore, research has delved into the regulation of inflammation in fibroblast-like synoviocytes from rheumatoid arthritis patients via LKB1-AMPK signaling pathways.

Kang has a significant publication record, with over 200 publications and a citation count of nearly 5,000, contributing to his h-index of 35. He has collaborated with several researchers at the University of Arkansas at Fayetteville, including Sara Orlowski, Wayne J. Kuenzel, and Michael T. Kidd.

Metrics

• h-index: 35
• Publications: 203
• Citations: 4,795