Shannon L. Servoss
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Also affiliated: Pacific Northwest National Laboratory (2009); University of Arkansas System (2018)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Shannon L. Servoss's research focuses on the design and application of peptoid-based materials. Her work investigates how peptoid chemistry can be manipulated to control the aggregation of amyloid-beta peptides, a process implicated in Alzheimer's disease. Servoss has explored the effects of side chain placement and chirality on amyloid-beta aggregation, as well as the development of peptoid microspheres with tunable properties based on side chain chemistry and sequence.
Beyond amyloid aggregation, Servoss's research extends to biomaterials for therapeutic applications. She has investigated the use of PEG-mimetic peptoids to reduce protein fouling on polysulfone hollow fibers and has received NSF funding for an I-Corps project on peptoid microsphere-coated surfaces for wound healing applications. Her publications also include work on biodegradable microneedle patches for drug delivery and the development of tools for high-throughput analysis of biological samples, such as antibody microarrays.
Servoss's scholarship metrics include an h-index of 10, with 28 total publications and 264 total citations. She has served as PI on one federal grant from the NSF for $50,000, focusing on peptoid microsphere-coated surfaces for wound healing treatment. Her collaborations include work with researchers at the University of Arkansas at Fayetteville, such as Mohan Yasodharababu, Frank O. Aparicio-Solis, Katherine A. Miranda-Muñoz, and Lauren F. Greenlee.
Metrics
- h-index: 10
- Publications: 28
- Citations: 264
Selected Publications
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Incorporating Inquiry-Based Projects into the Early Lab Experience (2025)
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A Simple Point-of-Care Device for Temperature Control of Multiple Reactions During Recombinase Polymerase Amplification (2024)
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Rationally Designed Peptoid Inhibitors of Amyloid‐β Oligomerization (2024)
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Modulating the RAGE‐Induced Inflammatory Response: Peptoids as RAGE Antagonists (2023)
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Peptoids as potential therapeutics to reduce S100B-induced RAGE-associated neuroinflammation in Alzheimer's disease (2023)
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Delivery of Immobilized IFN-γ With PCN-333 and Its Effect on Human Mesenchymal Stem Cells (2023)
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Biodegradable microneedle patch for delivery of meloxicam for managing pain in cattle (2022)
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Peptoid microsphere coatings to improve performance in sandwich ELISA microarrays (2021)
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Interaction energy between neuronal cell receptors and peptoid ligands (2021)
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Ten simple rules for women principal investigators during a pandemic (2020)
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Abstract P102: Generation Of A Novel Peptoid-peptide Analog Of Alpha-calcitonin Gene Related Peptide (α-CGRP) For The Treatment And Prevention Of Cardiovascular Diseases (2020)
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Levels of plasma glycan-binding auto-IgG biomarkers improve the accuracy of prostate cancer diagnosis (2020)
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Low Fouling, Peptoid-Coated Polysulfone Hollow Fiber Membranes—the Effect of Grafting Density and Number of Side Chains (2019)
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Peptoid microsphere coatings: The effects of helicity, temperature, pH, and ionic strength (2019)
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Altering the edge chemistry of bicelles with peptoids (2018)
Federal Grants 1 $50,000 total
I-Corps: Peptoid microsphere-coated surfaces for use in treatment of wound healing
Collaboration Network
Top Collaborators
- Rationally Designed Peptoids Modulate Aggregation of Amyloid-Beta 40
- Modulating amyloid-β aggregation: The effects of peptoid side chain placement and chirality
- Modulating the RAGE‐Induced Inflammatory Response: Peptoids as RAGE Antagonists
- Rationally Designed Peptoid Inhibitors of Amyloid‐β Oligomerization
- The Effect of Peptoids on Aβ Aggregation and NF-κB Activation in Alzheimer's Disease
Showing 5 of 6 shared publications
- Rationally Designed Peptoids Modulate Aggregation of Amyloid-Beta 40
- Tunable peptoid microspheres: effects of side chain chemistry and sequence
- Modulating amyloid-β aggregation: The effects of peptoid side chain placement and chirality
- The Effect of Peptoids on Aβ Aggregation and NF-κB Activation in Alzheimer's Disease
- Biodegradable microneedle patch for delivery of meloxicam for managing pain in cattle
- Peptoid microsphere coatings: The effects of helicity, temperature, pH, and ionic strength
- Low Fouling, Peptoid-Coated Polysulfone Hollow Fiber Membranes—the Effect of Grafting Density and Number of Side Chains
- Peptoid microsphere coatings to improve performance in sandwich ELISA microarrays
- Rationally Designed Peptoids Modulate Aggregation of Amyloid-Beta 40
- Rationally Designed Peptoid Inhibitors of Amyloid‐β Oligomerization
- The Effect of Peptoids on Aβ Aggregation and NF-κB Activation in Alzheimer's Disease
- Modulating the RAGE‐Induced Inflammatory Response: Peptoids as RAGE Antagonists
- Rationally Designed Peptoid Inhibitors of Amyloid‐β Oligomerization
- The Effect of Peptoids on Aβ Aggregation and NF-κB Activation in Alzheimer's Disease
- Modulating the RAGE‐Induced Inflammatory Response: Peptoids as RAGE Antagonists
- Rationally Designed Peptoid Inhibitors of Amyloid‐β Oligomerization
- Peptoids as potential therapeutics to reduce S100B-induced RAGE-associated neuroinflammation in Alzheimer's disease
- Tunable peptoid microspheres: effects of side chain chemistry and sequence
- Uniform and Robust Peptoid Microsphere Coatings
- Tunable peptoid microspheres: effects of side chain chemistry and sequence
- Uniform and Robust Peptoid Microsphere Coatings
- Peptoid microsphere coatings: The effects of helicity, temperature, pH, and ionic strength
- Peptoid microsphere coatings to improve performance in sandwich ELISA microarrays
- Biodegradable microneedle patch for delivery of meloxicam for managing pain in cattle
- Delivery of Immobilized IFN-γ With PCN-333 and Its Effect on Human Mesenchymal Stem Cells
- Tunable peptoid microspheres: effects of side chain chemistry and sequence
- Uniform and Robust Peptoid Microsphere Coatings
- Rationally Designed Peptoids Modulate Aggregation of Amyloid-Beta 40
- Rationally Designed Peptoids Modulate Aggregation of Amyloid-Beta 40
- Rationally Designed Peptoids Modulate Aggregation of Amyloid-Beta 40
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