Alzheimer'S Disease Research And Treatments
49 researchers across 5 institutions
Research in Alzheimer's disease and related dementias investigates the complex biological mechanisms underlying neurodegeneration and explores potential therapeutic interventions. Studies focus on understanding the formation and spread of protein aggregates, such as amyloid-beta and tau, and their impact on neuronal function and survival. This includes examining genetic predispositions, the role of neuroinflammation, metabolic dysregulation, and mitochondrial dysfunction in disease progression. Researchers employ a range of methodologies, from molecular biology and cell culture models to advanced imaging techniques and clinical studies, aiming to identify biomarkers for early detection and develop novel treatment strategies.
This area of study holds significant relevance for Arkansas. As the state, like many others, faces an aging population, understanding and treating Alzheimer's disease is a growing public health priority. Research contributes to developing strategies that could potentially alleviate the burden on families and the healthcare system. Furthermore, collaborations with state agencies and healthcare providers can inform public health initiatives and improve care for affected individuals across Arkansas.
This research is inherently interdisciplinary, drawing upon expertise in neuroscience, pharmacology, genetics, biochemistry, and clinical medicine. Engagement spans multiple institutions within Arkansas, fostering a collaborative environment to tackle the multifaceted challenges of Alzheimer's disease and advance neurological disorder treatments.
Top Researchers
| Name | Institution | h-index | Citations | Career Stage | Badges |
|---|---|---|---|---|---|
| W. Sue T. Griffin | UAMS | 66 | 17,576 | Grant PI High Impact | |
| Steven W. Barger | UAMS | 50 | 10,341 | Grant PI High Impact | |
| Philip Palade | UAMS | 39 | 5,125 | High Impact | |
| V. Tiwari | University of Arkansas | 39 | 5,171 | ||
| Qiang Shi | NCTR | 35 | 10,670 | High Impact | |
| Sumit Sarkar | NCTR | 35 | 4,345 | High Impact | |
| Jiřı́ Novotný | University of Arkansas | 33 | 6,504 | High Impact | |
| Srinivas Ayyadevara | UAMS | 31 | 5,423 | High Impact Grants | |
| Ruby Charak | UAMS | 25 | 2,098 | ||
| Sharda P. Singh | UAMS | 25 | 2,600 | High Impact | |
| Ling Liu | UAMS | 24 | 3,130 | High Impact | |
| Meenakshisundaram Balasubramaniam | UAMS | 23 | 1,275 | High Impact | |
| Héctor Rosas-Hernández | NCTR | 20 | 1,024 | ||
| Prabhash Nath Tripathi | UAMS | 20 | 1,728 | High Impact | |
| Chhanda Bose | UAMS | 20 | 1,078 | High Impact | |
| Shitiz Sriwastava | UAMS | 19 | 1,883 | ||
| James Raymick | NCTR | 18 | 1,098 | ||
| Varsha Karunakaran | University of Arkansas | 16 | 807 | ||
| Milan Patel | Arkansas State University | 15 | 941 | ||
| Dongjoon Lee | UAMS | 11 | 1,865 |
Related Research Areas
Strategic Outlook
Global signals from OpenAlex for this research area: where the field is growing, how concentrated leadership is, and where Arkansas sits relative to the world's top-100 institutions. Descriptive only — surfaced as input to the conversation about where to place bets, not a recommendation. Signal confidence: LOW
Top US institutions in this area
- 1 Harvard University 4,964
- 2 Massachusetts General Hospital 3,535
- 3 University of California, San Francisco 2,959
- 4 University of Pennsylvania 2,799
- 5 Washington University in St. Louis 2,748
Cross-Institution Connections
Researchers at different institutions with overlapping expertise in Alzheimer'S Disease Research And Treatments.