Jeffery W. Fisher
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Also affiliated: United States Food and Drug Administration (2011–2023); Battelle (1998); Pacific Northwest National Laboratory (1998); University of Georgia (2009–2010); Wright-Patterson Air Force Base (1993–1994); Armstrong Laboratory (1993)
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Jeffery W. Fisher's research investigates the cellular and molecular mechanisms underlying chemical-induced cytotoxicity, with a focus on kidney cells. His work has examined the effects of bromate on human and rat kidney cells, employing cell line models for these studies. Fisher has also explored the variability of physiologically based pharmacokinetic (PBPK) model parameters in risk assessment for chemicals like tetrachloroethylene (PCE).
His research has involved the development and application of PBPK models to simulate the transfer and metabolism of various substances, including tetrachloroethylene in rats and 2,2-dichloro-1,1,1-trifluoroethane in rats. Fisher's publications also include studies on hormonal modulation of the hypothalamic–pituitary–adrenal (HPA) axis in rhesus monkeys and the effects of leptin administration on hormone concentrations in juvenile female rhesus monkeys. He has a h-index of 7 with 18 total publications and 467 citations.
Metrics
- h-index: 7
- Publications: 13
- Citations: 278
Selected Publications
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Physiologically based pharmacokinetic modeling of oseltamivir in pregnant rhesus macaques to inform clinical dosing across trimesters (2025)
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Evaluation of a microphysiological human placental barrier model for studying placental drug transfer (2023)
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Considerations for Applying Route-to-Route Extrapolation to Assess the Safety of Oral Exposure to Substances (2022)
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Creatinine‐Based Renal Function Assessment in Pediatric Drug Development: An Analysis Using Clinical Data for Renally Eliminated Drugs (2020)
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Pharmacokinetics of oseltamivir phosphate and oseltamivir carboxylate in non-pregnant and pregnant rhesus monkeys (2020)
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Per- and polyfluoroalkyl substances in human serum and urine samples from a residentially exposed community (2017)
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The synergistic effect of sodium chlorite and bromochloroacetic acid on BrO3−-induced renal cell death (2011)
Collaboration Network
Top Collaborators
- Pharmacokinetics of oseltamivir phosphate and oseltamivir carboxylate in non-pregnant and pregnant rhesus monkeys
- Physiologically based pharmacokinetic modeling of oseltamivir in pregnant rhesus macaques to inform clinical dosing across trimesters
- Pharmacokinetics of oseltamivir phosphate and oseltamivir carboxylate in non-pregnant and pregnant rhesus monkeys
- Physiologically based pharmacokinetic modeling of oseltamivir in pregnant rhesus macaques to inform clinical dosing across trimesters
- Pharmacokinetics of oseltamivir phosphate and oseltamivir carboxylate in non-pregnant and pregnant rhesus monkeys
- Physiologically based pharmacokinetic modeling of oseltamivir in pregnant rhesus macaques to inform clinical dosing across trimesters
- Evaluation of a microphysiological human placental barrier model for studying placental drug transfer
- Physiologically based pharmacokinetic modeling of oseltamivir in pregnant rhesus macaques to inform clinical dosing across trimesters
- The synergistic effect of sodium chlorite and bromochloroacetic acid on BrO3−-induced renal cell death
- The synergistic effect of sodium chlorite and bromochloroacetic acid on BrO3−-induced renal cell death
- The synergistic effect of sodium chlorite and bromochloroacetic acid on BrO3−-induced renal cell death
- The synergistic effect of sodium chlorite and bromochloroacetic acid on BrO3−-induced renal cell death
- Per- and polyfluoroalkyl substances in human serum and urine samples from a residentially exposed community
- Per- and polyfluoroalkyl substances in human serum and urine samples from a residentially exposed community
- Per- and polyfluoroalkyl substances in human serum and urine samples from a residentially exposed community
- Per- and polyfluoroalkyl substances in human serum and urine samples from a residentially exposed community
- Per- and polyfluoroalkyl substances in human serum and urine samples from a residentially exposed community
- Per- and polyfluoroalkyl substances in human serum and urine samples from a residentially exposed community
- Per- and polyfluoroalkyl substances in human serum and urine samples from a residentially exposed community
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