Gregory L. Smith

Assistant Professor/MD

UAMS

Also affiliated: Cincinnati Children's Hospital Medical Center (2017); Boeing (United States) (1994); State University of New York (1994); University of Wisconsin–Madison (1992); Harvard University (1989); University of Cape Town (2025); Pfizer (United States) (2014–2016); Georgetown University (2004); Pfizer (United Kingdom) (2015); Beaumont Health (2020); Georgetown University Medical Center (2004); Luton and Dunstable Hospital (1996); United States Department of the Navy (1985); Middlesex Hospital (1992); Futures Group (United States) (2002); Shriners Hospitals for Children - Cincinnati (1982); Burn Institute (1982); Resolve Therapeutics (United States) (2024); Defense Systems (United States) (1994); North Middlesex Hospital (1992); Celldex Therapeutics (United States) (2022); United States Navy (1985); University of Cincinnati (1996–2017); Royal College of Psychiatrists (2014); Oklahoma State University Center for Health Sciences (1978); Saint Petersburg State Pediatric Medical University (2021); McMaster University (2007–2012)

Faculty Researcher

Anesthesiology, College of Medicine

17 h-index 70 pubs 805 cited

Research Areas

Biomedical Subjects

Links

ORCID Lab Website Research Group UAMS TRI Profile

OverviewAI-generated summary

Gregory L. Smith is an Assistant Professor in the Department of Anesthesiology at the University of Arkansas for Medical Sciences, College of Medicine. His research focuses on the study and application of neuromodulation techniques for managing chronic and persistent pain, particularly in the context of postoperative recovery. He has investigated the efficacy of percutaneous peripheral nerve stimulation and spinal cord stimulation (SCS) for improving pain relief and function in patients following orthopedic procedures, such as knee replacement. Smith's work also explores factors influencing treatment success, including psychosocial elements and immediate programming responses in SCS trials.

His scholarly contributions include studies on novel therapeutic agents, such as cannabidiol (CBD) and tetrahydrocannabivarin (THCV), for conditions ranging from hair regrowth to weight management. Smith has also been involved in developing consensus guidelines for neuromodulation training programs. With an h-index of 16 and over 70 publications, his research is supported by collaborations with colleagues at the University of Arkansas for Medical Sciences, including Johnathan Goree, Jarna Shah, and Erika Petersen.

Metrics

h-index: 17
Publications: 70
Citations: 805

Selected Publications

Durable Outcomes and Intervention Avoidance in Low Back Pain Up to 5 Years After Percutaneous 60-Day Peripheral Nerve Stimulation (2026)

Pain and Therapy DOI OpenAlex
Correction: Next‑Generation SCS Programming Platform: Enhancing ECAP Fidelity and Objectivity to Improve Patient Experience (2026)

Pain and Therapy DOI OpenAlex
The American Society of Pain and Neuroscience (ASPN) Evidence-Based Consensus Recommendations on Programming and Coding Implantable Spinal Cord Stimulation Devices for Treatment of Chronic Intractable Pain (2026)

Journal of Pain Research DOI OpenAlex
Next-Generation SCS Programming Platform: Enhancing ECAP Fidelity and Objectivity to Improve Patient Experience (2026)

Pain and Therapy 1 citation DOI OpenAlex
Clinical utility of ECAP dosing in a real-world population delivered via EVOKE therapy: the ECAP study (2025)

Regional Anesthesia & Pain Medicine 2 citations DOI OpenAlex
First Objective Evidence Characterizing Differences in Cervical and Thoracic Spinal Cord Neurophysiology Using ECAP-Controlled Closed-Loop Technology (2025)

Pain and Therapy DOI OpenAlex
ID# 1904716 Efficacy of Radiofrequency Ablation using Multi-Tined Electrodes vs. Protruding Electrodes for Lumbar Spondylosis (2025)

Neuromodulation Technology at the Neural Interface DOI OpenAlex
ID# 1906098 ECAP Study Premiere: Real-World IDE Study Showing Relationship between Physiologic ECAP Biomarkers and Pain Outcomes (2025)

Neuromodulation Technology at the Neural Interface DOI OpenAlex
Significant pain reduction in refractory post-mastectomy pain syndrome with closed-loop spinal cord stimulation: illustrative cases. (2025)

PubMed DOI OpenAlex
ECAP-Controlled Closed-Loop Spinal Cord Stimulation for Chronic Nonsurgical Refractory Back Pain (2025)

Spine 4 citations DOI OpenAlex
ID: 342895 Assessment of Psychosocial Factors and Success of Neuromodulation Trials for Treatment of Persistent Pain (2024)

Neuromodulation Technology at the Neural Interface DOI OpenAlex
Identifying SCS Trial Responders Immediately After Postoperative Programming with ECAP Dose-Controlled Closed-Loop Therapy (2024)

Pain and Therapy 10 citations DOI OpenAlex
Randomized Placebo-Controlled Trial of 60-Day Percutaneous Peripheral Nerve Stimulation Treatment Indicates Relief of Persistent Postoperative Pain, and Improved Function After Knee Replacement (2024)

Neuromodulation Technology at the Neural Interface 30 citations DOI OpenAlex
Impact of psychosocial factors on the success of neuromodulation treatment for patients with persistent pain (2024)

Regional Anesthesia & Pain Medicine 9 citations DOI OpenAlex
Pain Education and Knowledge (PEAK) Consensus Guidelines for Neuromodulation: A Proposal for Standardization in Fellowship and Training Programs (2023)

Journal of Pain Research 18 citations DOI OpenAlex