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Presence Current · Arkansas
Last published 2025
Sources OpenAlex · ORCID
Refreshed 2026-08-15

Ashley V. Nywening

Researcher

Also affiliated: University of Tennessee Health Science Center (2019–2025); Translational Sciences (United States) (2020–2021)

Faculty Researcher

8 h-index 17 pubs 301 cited

  • Aspergillus fumigatus
  • Fungal Proteins
  • Antifungal Agents
  • Aspergillosis
  • Triazoles
  • Humans
  • Animals
  • Drug Resistance, Fungal
  • Gene Expression Regulation, Fungal
  • Mice
  • Ergosterol
  • Microbial Sensitivity Tests
  • Aspergillus
  • Virulence
  • Hyphae

Biography and Research Information

OverviewAI-generated summary

Ashley V. Nywening's research investigates mechanisms of fungal pathogenesis and antifungal drug action, with a specific focus on *Aspergillus fumigatus*. Her work has explored the role of fungal genes and proteins in host-pathogen interactions and the development of resistance to antifungal therapies. Recent publications examine the function of erg6 in fungal viability, the contribution of the maiA gene to the cell wall and virulence, and novel mechanisms of triazole antifungal action mediated by the hmg1 gene. Nywening has also studied the regulation of fungal growth and invasion by conserved kinases and signaling pathways, such as the septation initiation network (SIN), and how disruption of these pathways can impact antifungal drug efficacy. Her research contributes to understanding fungal biology and developing strategies to combat fungal infections.

Metrics

  • h-index: 8
  • Publications: 17
  • Citations: 301

Selected Publications

  • Genetic analysis of common triazole resistance mechanisms in a collection of <i>Aspergillus lentulus</i> clinical isolates from the United States (2025)
    Antimicrobial Agents and Chemotherapy 1 citation DOI OpenAlex

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Collaboration Network

5 Collaborators 2 Institutions 2 Countries

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