Amanda L. Dragan
Researcher
Also affiliated: University of Mount Union (2015)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Amanda L. Dragan's research focuses on host-pathogen interactions, particularly concerning the bacterium *Coxiella burnetii*, the causative agent of Q fever. Her work investigates how this pathogen invades host cells and elicits inflammatory responses. Dr. Dragan has explored the potential of repurposing existing drugs, specifically neurotransmitter system-targeting agents, as novel treatments against *Coxiella burnetii* infections in human cells. She has also examined the development of new antibacterial derivatives, including work on the late-stage functionalization of the rifamycin core via click chemistry. Her research utilizes biological models, including primary human lung tissue, to study pathogen invasion. Dr. Dragan collaborates with other researchers at the University of Arkansas for Medical Sciences, including Daniel E. Voth and Anette Dragan.
Metrics
- h-index: 5
- Publications: 7
- Citations: 166
Selected Publications
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Late-Stage Functionalization of the Rifamycin Core via Click Chemistry Toward New Antibacterial Derivatives (2026)
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Coxiella burnetii Strains Elicit Distinct Inflammatory Responses in Human Macrophages (2025)
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<i>Coxiella burnetii</i> strains elicit distinct inflammatory responses in human macrophages (2025)
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Neurotransmitter System-Targeting Drugs Antagonize Growth of the Q Fever Agent, Coxiella burnetii, in Human Cells (2021)
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Take my breath away: studying pathogen invasion of the human lung using primary tissue models (2021)
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Coxiella burnetii: international pathogen of mystery (2019)
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Characterization of Early Stages of Human Alveolar Infection by the Q Fever Agent <i>Coxiella burnetii</i> (2019)
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Coxiella burnetii Subverts p62/Sequestosome 1 and Activates Nrf2 Signaling in Human Macrophages (2018)
Collaboration Network
Top Collaborators
- Take my breath away: studying pathogen invasion of the human lung using primary tissue models
- Neurotransmitter System-Targeting Drugs Antagonize Growth of the Q Fever Agent, Coxiella burnetii, in Human Cells
- <i>Coxiella burnetii</i> strains elicit distinct inflammatory responses in human macrophages
- Coxiella burnetii Strains Elicit Distinct Inflammatory Responses in Human Macrophages
- Neurotransmitter System-Targeting Drugs Antagonize Growth of the Q Fever Agent, Coxiella burnetii, in Human Cells
- Late-Stage Functionalization of the Rifamycin Core via Click Chemistry Toward New Antibacterial Derivatives
- <i>Coxiella burnetii</i> strains elicit distinct inflammatory responses in human macrophages
- Coxiella burnetii Strains Elicit Distinct Inflammatory Responses in Human Macrophages
- <i>Coxiella burnetii</i> strains elicit distinct inflammatory responses in human macrophages
- Coxiella burnetii Strains Elicit Distinct Inflammatory Responses in Human Macrophages
- Neurotransmitter System-Targeting Drugs Antagonize Growth of the Q Fever Agent, Coxiella burnetii, in Human Cells
- Neurotransmitter System-Targeting Drugs Antagonize Growth of the Q Fever Agent, Coxiella burnetii, in Human Cells
- Neurotransmitter System-Targeting Drugs Antagonize Growth of the Q Fever Agent, Coxiella burnetii, in Human Cells
- <i>Coxiella burnetii</i> strains elicit distinct inflammatory responses in human macrophages
- Coxiella burnetii Strains Elicit Distinct Inflammatory Responses in Human Macrophages
- Late-Stage Functionalization of the Rifamycin Core via Click Chemistry Toward New Antibacterial Derivatives
- Late-Stage Functionalization of the Rifamycin Core via Click Chemistry Toward New Antibacterial Derivatives
- Late-Stage Functionalization of the Rifamycin Core via Click Chemistry Toward New Antibacterial Derivatives
- Late-Stage Functionalization of the Rifamycin Core via Click Chemistry Toward New Antibacterial Derivatives
- Late-Stage Functionalization of the Rifamycin Core via Click Chemistry Toward New Antibacterial Derivatives
- Late-Stage Functionalization of the Rifamycin Core via Click Chemistry Toward New Antibacterial Derivatives
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