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Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-08

Amanda L. Dragan

Researcher

Also affiliated: University of Mount Union (2015)

Faculty Researcher

5 h-index 7 pubs 166 cited

  • Humans
  • Coxiella burnetii
  • Host-Pathogen Interactions
  • Q Fever
  • Anti-Bacterial Agents
  • Macrophages
  • Macrophages, Alveolar
  • Models, Biological
  • Rifamycins
  • Click Chemistry
  • Animals
  • Cytoplasm
  • Disease Models, Animal
  • Global Health
  • Sequestosome-1 Protein

Biography and Research Information

OverviewAI-generated summary

Amanda L. Dragan's research focuses on host-pathogen interactions, particularly concerning the bacterium *Coxiella burnetii*, the causative agent of Q fever. Her work investigates how this pathogen invades host cells and elicits inflammatory responses. Dr. Dragan has explored the potential of repurposing existing drugs, specifically neurotransmitter system-targeting agents, as novel treatments against *Coxiella burnetii* infections in human cells. She has also examined the development of new antibacterial derivatives, including work on the late-stage functionalization of the rifamycin core via click chemistry. Her research utilizes biological models, including primary human lung tissue, to study pathogen invasion. Dr. Dragan collaborates with other researchers at the University of Arkansas for Medical Sciences, including Daniel E. Voth and Anette Dragan.

Metrics

  • h-index: 5
  • Publications: 7
  • Citations: 166

Selected Publications

  • Late-Stage Functionalization of the Rifamycin Core via Click Chemistry Toward New Antibacterial Derivatives (2026)
    Molecules DOI OpenAlex
  • Coxiella burnetii Strains Elicit Distinct Inflammatory Responses in Human Macrophages (2025)
  • <i>Coxiella burnetii</i> strains elicit distinct inflammatory responses in human macrophages (2025)
  • Neurotransmitter System-Targeting Drugs Antagonize Growth of the Q Fever Agent, Coxiella burnetii, in Human Cells (2021)
    mSphere 5 citations DOI OpenAlex
  • Take my breath away: studying pathogen invasion of the human lung using primary tissue models (2021)
    Pathogens and Disease 5 citations DOI OpenAlex
  • Coxiella burnetii: international pathogen of mystery (2019)
    Microbes and Infection 95 citations DOI OpenAlex
  • Characterization of Early Stages of Human Alveolar Infection by the Q Fever Agent <i>Coxiella burnetii</i> (2019)
    Infection and Immunity 29 citations DOI OpenAlex
  • Coxiella burnetii Subverts p62/Sequestosome 1 and Activates Nrf2 Signaling in Human Macrophages (2018)
    Infection and Immunity 32 citations DOI OpenAlex

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Collaboration Network

26 Collaborators 9 Institutions 1 Country

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