Jian‐Min Yuan
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Biomedical Subjects
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Biography and Research Information
OverviewAI-generated summary
Jian-Min Yuan's research focuses on the investigation of risk factors and susceptibility loci associated with various cancers, including colorectal, lung, hepatocellular, and endometrial cancers. Yuan has published findings from large-scale prospective cohort studies, such as the Singapore Chinese Health Study, examining the interplay between diet, genetics, and cancer risk. Recent work has also explored the application of radiomics and machine learning in predicting pulmonary nodule malignancy and analyzing the blood proteome in relation to lung cancer diagnosis.
With a comprehensive publication record of 986 articles and over 37,000 citations, Yuan is recognized as a highly cited researcher. Collaborations include work with Nithya Neelakantan at the University of Arkansas for Medical Sciences. Yuan's extensive work contributes to understanding the genomic and molecular underpinnings of cancer development and detection.
Metrics
- h-index: 95
- Publications: 986
- Citations: 37,763
Selected Publications
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Hormone therapy use and young-onset breast cancer: a pooled analysis of prospective cohorts included in the Premenopausal Breast Cancer Collaborative Group (2025)
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Alcohol intake and pancreatic cancer risk: An analysis from 30 prospective studies across Asia, Australia, Europe, and North America (2025)
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Randomized Phase II Clinical Trial of Sulforaphane in Former Smokers at High Risk for Lung Cancer (2025)
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Design of Ligand‐Nonbridging Sites in Metal–Organic Frameworks for Boosting Lithium Storage Capacity (2024)
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The Epstein–Barr Virus Nuclear Antigen 1 Variant Associated with Nasopharyngeal Carcinoma Defines the Sequence Criteria for Serologic Risk Prediction (2024)
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Comparison of race‐ and ethnicity‐specific <scp>BMI</scp> cutoffs for categorizing obesity severity: a multicountry prospective cohort study (2024)
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Waterpipe Tobacco Smoking and Risk of Cancer Mortality (2024)
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Accurate Whole-Brain Segmentation for Bimodal PET/MR Images via a Cross-Attention Mechanism (2024)
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Genome-wide association study identifies high-impact susceptibility loci for HCC in North America (2024)
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Association between reproductive factors with lung cancer incidence and mortality: A pooled analysis of over 308,000 females in the Asia cohort consortium (2024)
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Genetic drivers of heterogeneity in type 2 diabetes pathophysiology (2024)
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Radiomics analysis to predict pulmonary nodule malignancy using machine learning approaches (2024)
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CYP2A6 Activity and Cigarette Consumption Interact in Smoking-Related Lung Cancer Susceptibility (2023)
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Obesity is associated with biliary tract cancer mortality and incidence: A pooled analysis of 21 cohort studies in the Asia Cohort Consortium (2023)
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Association of aflatoxin with gallbladder cancer in a case‐control study nested within a Chinese cohort (2023)
Collaboration Network
Top Collaborators
- A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma
- Green tea, black tea and breast cancer risk: a meta-analysis of epidemiological studies
- Association between type 2 diabetes and risk of cancer mortality: a pooled analysis of over 771,000 individuals in the Asia Cohort Consortium
- Differential Effects of Black versus Green Tea on Risk of Parkinson's Disease in the Singapore Chinese Health Study
- Tobacco Smoking and Mortality in Asia
Showing 5 of 85 shared publications
- Association between Body-Mass Index and Risk of Death in More Than 1 Million Asians
- Body Mass Index and Diabetes in Asia: A Cross-Sectional Pooled Analysis of 900,000 Individuals in the Asia Cohort Consortium
- Association between type 2 diabetes and risk of cancer mortality: a pooled analysis of over 771,000 individuals in the Asia Cohort Consortium
- Alcohol and Tobacco Use in Relation to Gastric Cancer: A Prospective Study of Men in Shanghai, China
- Urinary Levels of Tobacco-Specific Nitrosamine Metabolites in Relation to Lung Cancer Development in Two Prospective Cohorts of Cigarette Smokers
Showing 5 of 56 shared publications
- Epidemiology of nasopharyngeal carcinoma
- Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms, and lung-cancer risk: a prospective study of men in Shanghai, China
- Environmental factors and risk for hepatocellular carcinoma
- Synergism of alcohol, diabetes, and viral hepatitis on the risk of hepatocellular carcinoma in blacks and whites in the U.S.
- Green tea, black tea and breast cancer risk: a meta-analysis of epidemiological studies
Showing 5 of 54 shared publications
- Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms, and lung-cancer risk: a prospective study of men in Shanghai, China
- Risk factors for breast cancer in Chinese women in Shanghai.
- Follow up study of moderate alcohol intake and mortality among middle aged men in Shanghai, China
- Serum hormone levels in pre-menopausal Chinese women in Shanghai and white women in Los Angeles: results from two breast cancer case-control studies
- Population-based case-control study of ovarian cancer in Shanghai.
Showing 5 of 29 shared publications
- Association between Body-Mass Index and Risk of Death in More Than 1 Million Asians
- A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma
- Association between body mass index and cardiovascular disease mortality in east Asians and south Asians: pooled analysis of prospective data from the Asia Cohort Consortium
- Association between type 2 diabetes and risk of cancer mortality: a pooled analysis of over 771,000 individuals in the Asia Cohort Consortium
- Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations
Showing 5 of 17 shared publications
- Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study
- Detectable clonal mosaicism and its relationship to aging and cancer
- A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci
- Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types
- Genome-wide association study identifies multiple loci associated with bladder cancer risk
Showing 5 of 15 shared publications
- Association between type 2 diabetes and risk of cancer mortality: a pooled analysis of over 771,000 individuals in the Asia Cohort Consortium
- Composite dietary antioxidant index and the risk of colorectal cancer: Findings from the Singapore Chinese Health Study
- Association between Pre-Diagnostic Serum Bile Acids and Hepatocellular Carcinoma: The Singapore Chinese Health Study
- NAFLD polygenic risk score and risk of hepatocellular carcinoma in an East Asian population
- Serum Biomarkers of Iron Status and Risk of Hepatocellular Carcinoma Development in Patients with Nonalcoholic Fatty Liver Disease
Showing 5 of 15 shared publications
- Association between Body-Mass Index and Risk of Death in More Than 1 Million Asians
- A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma
- Tobacco Smoking and Mortality in Asia
- Association of Diabetes With All-Cause and Cause-Specific Mortality in Asia
- Alcohol and Tobacco Use in Relation to Gastric Cancer: A Prospective Study of Men in Shanghai, China
Showing 5 of 14 shared publications
- Urinary aflatoxin biomarkers and risk of hepatocellular carcinoma
- Gender- and Smoking-Related Bladder Cancer Risk
- Risk factors for breast cancer in Chinese women in Shanghai.
- Follow up study of moderate alcohol intake and mortality among middle aged men in Shanghai, China
- Differential Effects of Black versus Green Tea on Risk of Parkinson's Disease in the Singapore Chinese Health Study
Showing 5 of 13 shared publications
- Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms, and lung-cancer risk: a prospective study of men in Shanghai, China
- Use of permanent hair dyes and bladder-cancer risk
- Epidemiology of Hepatocellular Carcinoma
- Lipid peroxidation: a novel and unifying concept of the etiology of renal cell carcinoma (United States)
- Non-dietary risk factors for nasopharyngeal carcinoma in Shanghai, China
Showing 5 of 13 shared publications
- Gender- and Smoking-Related Bladder Cancer Risk
- Use of permanent hair dyes and bladder-cancer risk
- Lipid peroxidation: a novel and unifying concept of the etiology of renal cell carcinoma (United States)
- Cruciferous vegetables in relation to renal cell carcinoma
- Dietary sources of N‐nitroso compounds and bladder cancer risk: Findings from the Los Angeles bladder cancer study
Showing 5 of 12 shared publications
- Urinary Levels of Tobacco-Specific Nitrosamine Metabolites in Relation to Lung Cancer Development in Two Prospective Cohorts of Cigarette Smokers
- Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China
- Urinary Levels of Cigarette Smoke Constituent Metabolites Are Prospectively Associated with Lung Cancer Development in Smokers
- Applying Tobacco Carcinogen and Toxicant Biomarkers in Product Regulation and Cancer Prevention
- Urinary Tobacco Smoke–Constituent Biomarkers for Assessing Risk of Lung Cancer
Showing 5 of 12 shared publications
- Western-Style Fast Food Intake and Cardiometabolic Risk in an Eastern Country
- Dietary Patterns and Incident Type 2 Diabetes in Chinese Men and Women
- Combined Lifestyle Factors and Cardiovascular Disease Mortality in Chinese Men and Women
- Omega-3 fatty acids and incident type 2 diabetes: the Singapore Chinese Health Study
- Soy intake and risk of type 2 diabetes mellitus in Chinese Singaporeans
Showing 5 of 12 shared publications
- Tea and cancer prevention: Epidemiological studies
- Dietary Patterns and Incident Type 2 Diabetes in Chinese Men and Women
- A vegetable-fruit-soy dietary pattern protects against breast cancer among postmenopausal Singapore Chinese women
- Urinary Tobacco Smoke–Constituent Biomarkers for Assessing Risk of Lung Cancer
- Genetic and environmental predictors of serum 25-hydroxyvitamin D concentrations among middle-aged and elderly Chinese in Singapore
Showing 5 of 12 shared publications
- Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
- Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention
- A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure
- Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels
- Interethnic analyses of blood pressure loci in populations of East Asian and European descent
Showing 5 of 12 shared publications
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