Jian‐Min Yuan
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Faculty Researcher
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Biomedical Subjects
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Biography and Research Information
OverviewAI-generated summary
Jian-Min Yuan's research focuses on the investigation of risk factors and susceptibility loci associated with various cancers, including colorectal, lung, hepatocellular, and endometrial cancers. Yuan has published findings from large-scale prospective cohort studies, such as the Singapore Chinese Health Study, examining the interplay between diet, genetics, and cancer risk. Recent work has also explored the application of radiomics and machine learning in predicting pulmonary nodule malignancy and analyzing the blood proteome in relation to lung cancer diagnosis.
With a comprehensive publication record of 986 articles and over 37,000 citations, Yuan is recognized as a highly cited researcher. Collaborations include work with Nithya Neelakantan at the University of Arkansas for Medical Sciences. Yuan's extensive work contributes to understanding the genomic and molecular underpinnings of cancer development and detection.
Metrics
- h-index: 95
- Publications: 986
- Citations: 37,763
Selected Publications
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Hormone therapy use and young-onset breast cancer: a pooled analysis of prospective cohorts included in the Premenopausal Breast Cancer Collaborative Group (2025)
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Alcohol intake and pancreatic cancer risk: An analysis from 30 prospective studies across Asia, Australia, Europe, and North America (2025)
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Randomized Phase II Clinical Trial of Sulforaphane in Former Smokers at High Risk for Lung Cancer (2025)
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Design of Ligand‐Nonbridging Sites in Metal–Organic Frameworks for Boosting Lithium Storage Capacity (2024)
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The Epstein–Barr Virus Nuclear Antigen 1 Variant Associated with Nasopharyngeal Carcinoma Defines the Sequence Criteria for Serologic Risk Prediction (2024)
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Comparison of race‐ and ethnicity‐specific <scp>BMI</scp> cutoffs for categorizing obesity severity: a multicountry prospective cohort study (2024)
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Waterpipe Tobacco Smoking and Risk of Cancer Mortality (2024)
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Accurate Whole-Brain Segmentation for Bimodal PET/MR Images via a Cross-Attention Mechanism (2024)
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Genome-wide association study identifies high-impact susceptibility loci for HCC in North America (2024)
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Association between reproductive factors with lung cancer incidence and mortality: A pooled analysis of over 308,000 females in the Asia cohort consortium (2024)
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Genetic drivers of heterogeneity in type 2 diabetes pathophysiology (2024)
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Radiomics analysis to predict pulmonary nodule malignancy using machine learning approaches (2024)
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CYP2A6 Activity and Cigarette Consumption Interact in Smoking-Related Lung Cancer Susceptibility (2023)
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Obesity is associated with biliary tract cancer mortality and incidence: A pooled analysis of 21 cohort studies in the Asia Cohort Consortium (2023)
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Association of aflatoxin with gallbladder cancer in a case‐control study nested within a Chinese cohort (2023)
Collaboration Network
Top Collaborators
- Composite dietary antioxidant index and the risk of colorectal cancer: Findings from the Singapore Chinese Health Study
- Association between Pre-Diagnostic Serum Bile Acids and Hepatocellular Carcinoma: The Singapore Chinese Health Study
- The blood proteome of imminent lung cancer diagnosis
- NAFLD polygenic risk score and risk of hepatocellular carcinoma in an East Asian population
- Smoking and nasopharyngeal cancer: individual data meta-analysis of six prospective studies on 334 935 men
Showing 5 of 24 shared publications
- Composite dietary antioxidant index and the risk of colorectal cancer: Findings from the Singapore Chinese Health Study
- Association between Pre-Diagnostic Serum Bile Acids and Hepatocellular Carcinoma: The Singapore Chinese Health Study
- NAFLD polygenic risk score and risk of hepatocellular carcinoma in an East Asian population
- Serum Biomarkers of Iron Status and Risk of Hepatocellular Carcinoma Development in Patients with Nonalcoholic Fatty Liver Disease
- Smoking and nasopharyngeal cancer: individual data meta-analysis of six prospective studies on 334 935 men
Showing 5 of 21 shared publications
- Composite dietary antioxidant index and the risk of colorectal cancer: Findings from the Singapore Chinese Health Study
- Association between Pre-Diagnostic Serum Bile Acids and Hepatocellular Carcinoma: The Singapore Chinese Health Study
- NAFLD polygenic risk score and risk of hepatocellular carcinoma in an East Asian population
- Serum Biomarkers of Iron Status and Risk of Hepatocellular Carcinoma Development in Patients with Nonalcoholic Fatty Liver Disease
- The association between dietary vitamin B12 and lung cancer risk: findings from a prospective cohort study
Showing 5 of 14 shared publications
- Association between Pre-Diagnostic Serum Bile Acids and Hepatocellular Carcinoma: The Singapore Chinese Health Study
- Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population
- Serologic Profiling Using an Epstein-Barr Virus Mammalian Expression Library Identifies EBNA1 IgA as a Prediagnostic Marker for Nasopharyngeal Carcinoma
- Impact of Genetic Variants in the Nicotine Metabolism Pathway on Nicotine Metabolite Levels in Smokers
- The Association between Serum Serine and Glycine and Related-Metabolites with Pancreatic Cancer in a Prospective Cohort Study
Showing 5 of 8 shared publications
- Composite dietary antioxidant index and the risk of colorectal cancer: Findings from the Singapore Chinese Health Study
- Quality Diet Index and Risk of Pancreatic Cancer: Findings from the Singapore Chinese Health Study
- Neutrophil‐lymphocyte ratio in relation to risk of hepatocellular carcinoma in patients with non‐alcoholic fatty liver disease
- High serum magnesium is associated with lower risk of hepatocellular carcinoma among patients with nonalcoholic fatty liver disease
- The Association between Serum Serine and Glycine and Related-Metabolites with Pancreatic Cancer in a Prospective Cohort Study
Showing 5 of 8 shared publications
- Composite dietary antioxidant index and the risk of colorectal cancer: Findings from the Singapore Chinese Health Study
- Association between Pre-Diagnostic Serum Bile Acids and Hepatocellular Carcinoma: The Singapore Chinese Health Study
- NAFLD polygenic risk score and risk of hepatocellular carcinoma in an East Asian population
- Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population
- The association between dietary vitamin B12 and lung cancer risk: findings from a prospective cohort study
Showing 5 of 7 shared publications
- NAFLD polygenic risk score and risk of hepatocellular carcinoma in an East Asian population
- Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population
- Impact of Genetic Variants in the Nicotine Metabolism Pathway on Nicotine Metabolite Levels in Smokers
- Polygenic risk scores for the prediction of common cancers in East Asians: A population-based prospective cohort study
- A five-safes approach to a secure and scalable genomics data repository
Showing 5 of 7 shared publications
- Association between Body Mass Index and Risk of Gastric Cancer by Anatomic and Histologic Subtypes in Over 500,000 East and Southeast Asian Cohort Participants
- Serologic Profiling Using an Epstein-Barr Virus Mammalian Expression Library Identifies EBNA1 IgA as a Prediagnostic Marker for Nasopharyngeal Carcinoma
- The Association between Serum Serine and Glycine and Related-Metabolites with Pancreatic Cancer in a Prospective Cohort Study
- Association of aflatoxin with gallbladder cancer in a case‐control study nested within a Chinese cohort
- Obesity is associated with biliary tract cancer mortality and incidence: A pooled analysis of 21 cohort studies in the Asia Cohort Consortium
Showing 5 of 7 shared publications
- Association between Pre-Diagnostic Serum Bile Acids and Hepatocellular Carcinoma: The Singapore Chinese Health Study
- NAFLD polygenic risk score and risk of hepatocellular carcinoma in an East Asian population
- Serum Biomarkers of Iron Status and Risk of Hepatocellular Carcinoma Development in Patients with Nonalcoholic Fatty Liver Disease
- Neutrophil‐lymphocyte ratio in relation to risk of hepatocellular carcinoma in patients with non‐alcoholic fatty liver disease
- Impact of Genetic Variants in the Nicotine Metabolism Pathway on Nicotine Metabolite Levels in Smokers
Showing 5 of 6 shared publications
- The blood proteome of imminent lung cancer diagnosis
- Alcohol intake and pancreatic cancer risk: An analysis from 30 prospective studies across Asia, Australia, Europe, and North America
- A cross-sectional study of inflammatory markers as determinants of circulating kynurenines in the Lung Cancer Cohort Consortium
- CYP2A6 Activity and Cigarette Consumption Interact in Smoking-Related Lung Cancer Susceptibility
- Epidemiology of 40 blood biomarkers of one-carbon metabolism, vitamin status, inflammation, and renal and endothelial function among cancer-free older adults
Showing 5 of 6 shared publications
- Association between Body Mass Index and Risk of Gastric Cancer by Anatomic and Histologic Subtypes in Over 500,000 East and Southeast Asian Cohort Participants
- ABO genotypes and the risk of esophageal and gastric cancers
- A cross-sectional study of inflammatory markers as determinants of circulating kynurenines in the Lung Cancer Cohort Consortium
- Obesity is associated with biliary tract cancer mortality and incidence: A pooled analysis of 21 cohort studies in the Asia Cohort Consortium
- Association between reproductive factors with lung cancer incidence and mortality: A pooled analysis of over 308,000 females in the Asia cohort consortium
- The blood proteome of imminent lung cancer diagnosis
- Alcohol intake and pancreatic cancer risk: An analysis from 30 prospective studies across Asia, Australia, Europe, and North America
- CYP2A6 Activity and Cigarette Consumption Interact in Smoking-Related Lung Cancer Susceptibility
- Epidemiology of 40 blood biomarkers of one-carbon metabolism, vitamin status, inflammation, and renal and endothelial function among cancer-free older adults
- Mosaic Chromosomal Alterations Are Associated With Increased Lung Cancer Risk: Insight From the INTEGRAL-ILCCO Cohort Analysis
- Composite dietary antioxidant index and the risk of colorectal cancer: Findings from the Singapore Chinese Health Study
- Serum Biomarkers of Iron Status and Risk of Hepatocellular Carcinoma Development in Patients with Nonalcoholic Fatty Liver Disease
- Neutrophil‐lymphocyte ratio in relation to risk of hepatocellular carcinoma in patients with non‐alcoholic fatty liver disease
- High serum magnesium is associated with lower risk of hepatocellular carcinoma among patients with nonalcoholic fatty liver disease
- Low-Carbohydrate Diet Score and the Risk of Colorectal Cancer: Findings from the Singapore Chinese Health Study
- NAFLD polygenic risk score and risk of hepatocellular carcinoma in an East Asian population
- Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population
- Polygenic risk scores for the prediction of common cancers in East Asians: A population-based prospective cohort study
- The association of genetically determined serum glycine with cardiovascular risk in East Asians
- NAFLD polygenic risk score and risk of hepatocellular carcinoma in an East Asian population
- Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population
- A five-safes approach to a secure and scalable genomics data repository
- The association of genetically determined serum glycine with cardiovascular risk in East Asians
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