Cancer-Related Molecular Mechanisms Research

707 researchers across 16 institutions

707 Researchers
16 Institutions
63 Grant PIs
121 High Impact

Scientists investigate the fundamental molecular processes that drive cancer development, progression, and response to therapy. Research focuses on understanding how genetic mutations, epigenetic alterations, and cellular signaling pathways contribute to uncontrolled cell growth and metastasis. Investigations employ a range of molecular biology techniques, including genomics, proteomics, and advanced imaging, to identify key molecular targets and mechanisms underlying various cancer types. This work also explores how the tumor microenvironment and immune system interactions influence cancer biology and treatment efficacy.

This research holds particular relevance for Arkansas, a state with a significant burden of certain cancers. Understanding cancer-related molecular mechanisms can inform public health strategies and the development of targeted interventions to address disparities in cancer incidence and outcomes observed within the state's population. Furthermore, insights gained can contribute to the growth of the state's bioscience and biotechnology sectors, fostering innovation in diagnostics and therapeutics.

This area of study inherently connects to disciplines such as disease mechanisms, immune response, metabolism, and pharmacology. Research is conducted across multiple Arkansas institutions, fostering a broad base of expertise and collaboration.

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Top Researchers

Name Institution h-index Citations Career Stage Badges
Bart Barlogie UAMS 138 76,541 High Impact
Andrew N. J. McKenzie University of Arkansas 113 46,436 High Impact
Guido Tricot UAMS 97 36,409 High Impact
Jian‐Min Yuan University of Arkansas 95 37,763 High Impact
Thomas J. Kelly UAMS 90 29,658 High Impact
John D. Shaughnessy UAMS 88 31,240 High Impact
David M. Parham UAMS 81 21,213 High Impact
Jingyi Chen University of Arkansas 80 34,255 ARA Grant PI High Impact
Andrew Morris UAMS 77 22,261
Igor P. Pogribny NCTR 76 18,075 ARA High Impact
Thomas M. Badger UAMS 71 15,633 High Impact
Maurizio Zangari UAMS 71 19,446 High Impact
Fenghuang Zhan UAMS 67 19,235 Grant PI High Impact
W. Sue T. Griffin UAMS 66 17,576 Grant PI High Impact
Charles A. O’Brien UAMS 64 17,720 Grant PI High Impact
Shiv Srivastava UAMS 64 15,057 High Impact
Naveena Singh University of Arkansas – Fort Smith 64 16,943 High Impact
Luke R. Howard University of Arkansas 58 13,911 High Impact Grants
Frank A. Simmen UAMS 55 7,681 High Impact
Stepan Melnyk UAMS 55 10,973 High Impact
Disease Mechanisms Research 177 Molecular Biology Techniques And Applications 157 Immune Response And Inflammation 140 Metabolism And Genetic Disorders 133 Cancer Treatment And Pharmacology 128 Genomics And Phylogenetic Studies 110 Pharmacological Effects And Toxicity Studies 101 Health Disparities And Outcomes 96 Disease Models, Animal 81 Medical Imaging Techniques And Applications 78 Receptor Mechanisms And Signaling 62 Bioinformatics And Genomic Networks 61 Retrospective Studies 58 Health Sciences Research And Education 56 Diet And Metabolism Studies 55

Strategic Outlook

Global signals from OpenAlex for this research area: where the field is growing, how concentrated leadership is, and where Arkansas sits relative to the world's top-100 institutions. Descriptive only — surfaced as input to the conversation about where to place bets, not a recommendation. Signal confidence: LOW

Global trajectory
2 works in 2034
-42.9% CAGR 2018–2034
Leadership concentration
7.4% held by global top 5 institutions
Fragmented HHI 39
Arkansas position
Arkansas not in global top 100
No AR institution among the top-100 contributors to this topic over the 2018–2034 window.

Top US institutions in this area

  1. 1 Harvard University 2,426
  2. 2 The University of Texas MD Anderson Cancer Center 2,129
  3. 3 National Institutes of Health 1,287
  4. 4 Johns Hopkins University 1,277
  5. 5 Stanford University 1,192

Cross-Institution Connections

Researchers at different institutions with overlapping expertise in Cancer-Related Molecular Mechanisms Research.

Leonard Ferdman Arkansas State University
97%
Christina D. Miller UAMS
Leonard Ferdman Arkansas State University
92%
Malik Rettiganti UAMS
Ruizong Li UAMS
80%
Sam Davis Omekara Philander Smith College
Lauren Eads UAMS
78%
Shanique Murray University of Arkansas
Ebony Cotton NCTR
78%
Luke Enemark UAMS
Leonard Ferdman Arkansas State University
76%
Christophe Bobda UAMS
Khariana L. Hobbs UAMS
76%
Riley K Russo University of Arkansas
Leonard Ferdman Arkansas State University
74%
S. G. Lamb UAMS
Colin Furrow University of Arkansas
74%
Yaya Guo UAMS
John Davis UAMS
74%
Jessica Thrush University of Arkansas

Researchers with Federal Grants

Jingyi Chen University of Arkansas 6 grants J. Craig Forrest UAMS 5 grants Mark Manzano UAMS 4 grants Ren Xu UAMS 4 grants Kathleen Murphy UAMS 4 grants Brian Koss UAMS 3 grants Xuan Zhuang University of Arkansas 3 grants Alan J. Tackett UAMS 3 grants Charles A. O’Brien UAMS 3 grants Melanie C MacNicol UAMS 3 grants Jianfeng Xu Arkansas State University 3 grants Lu Dai UAMS 3 grants Narasimhan Rajaram University of Arkansas 3 grants Young Hye Song University of Arkansas 3 grants J. Leung UAMS 3 grants Murat Gökden UAMS 2 grants Robert L. Eoff UAMS 2 grants Ping-Ching Hsu UAMS 2 grants Martin J. Cannon UAMS 2 grants Vinay Raj UA Pine Bluff 2 grants
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