Cancer-Related Molecular Mechanisms Research
599 researchers across 14 institutions
Scientists investigate the fundamental molecular processes that drive cancer development and progression. This research delves into how genetic mutations, epigenetic alterations, and cellular signaling pathways contribute to uncontrolled cell growth, metastasis, and resistance to therapy. Studies employ a range of techniques, including genomics, proteomics, and advanced imaging, to identify novel biomarkers for early detection and therapeutic targets. Specific areas of focus include understanding the molecular basis of various cancer types, examining the role of metabolism in tumor growth, and exploring the complex interactions between cancer cells and the tumor microenvironment.
The state of Arkansas experiences significant cancer burdens, making research into cancer-related molecular mechanisms particularly relevant to public health initiatives. Understanding these mechanisms can inform strategies for cancer prevention, diagnosis, and treatment tailored to the specific health needs and demographic profiles of Arkansas's population. Furthermore, this research has the potential to foster economic growth through the development of new diagnostic tools and therapeutic agents, supporting the state's biosciences sector.
This area of study draws upon expertise from molecular biology, genetics, biochemistry, and pharmacology. Investigations are conducted across multiple institutions in Arkansas, fostering collaboration and interdisciplinary approaches to address complex questions in cancer biology. The research engages faculty, postdoctoral researchers, and graduate students, contributing to the training of the next generation of scientists.
Top Researchers
| Name | Institution | h-index | Citations | Career Stage | Badges |
|---|---|---|---|---|---|
| Bart Barlogie | UAMS | 139 | 77,164 | High Impact | |
| Guido J. K. Tricot | UAMS | 96 | 36,453 | Faculty | High Impact |
| John D. Shaughnessy | UAMS | 89 | 31,735 | Faculty | High Impact |
| Thomas J. Kelly | UAMS | 89 | 29,180 | Faculty | High Impact |
| Frits van Rhee | UAMS | 83 | 27,050 | Faculty | High Impact |
| Igor P. Pogribny | NCTR | 76 | 18,238 | ARA High Impact | |
| Mário G. Ferruzzi | UAMS | 72 | 16,459 | Faculty | High Impact |
| Frederick A. Beland | NCTR | 71 | 19,281 | High Impact | |
| Maurizio Zangari | UAMS | 71 | 19,736 | Faculty | High Impact |
| Fenghuang Zhan | UAMS | 68 | 19,565 | Faculty | Grant PI High Impact |
| Naveena Singh | Arkansas Colleges of Health Education | 64 | 16,943 | High Impact | |
| Jerry Ware | UAMS | 60 | 13,312 | Faculty | High Impact Grants |
| Luke R. Howard | University of Arkansas | 58 | 13,877 | Faculty | High Impact Grants |
| Peter Anthony Crooks | UAMS | 57 | 15,023 | ARA High Impact | |
| Mario Schootman | UAMS | 56 | 14,261 | Faculty | Grant PI High Impact |
| M. Emre Celebi | University of Central Arkansas | 54 | 14,994 | Faculty | High Impact |
| Eric R. Siegel | UAMS | 52 | 10,228 | Postdoctoral | High Impact |
| Laura Phillips James | UAMS | 52 | 10,522 | Faculty | ARA Grant PI |
| Mona I. Churchwell | NCTR | 50 | 6,998 | High Impact | |
| Cheng‐Wen Wu | Arkansas Tech University | 49 | 9,508 |
Related Research Areas
Strategic Outlook
Global signals from OpenAlex for this research area: where the field is growing, how concentrated leadership is, and where Arkansas sits relative to the world's top-100 institutions. Descriptive only — surfaced as input to the conversation about where to place bets, not a recommendation. Signal confidence: LOW
Top US institutions in this area
- 1 The University of Texas MD Anderson Cancer Center 1,564
- 2 Harvard University 1,524
- 3 National Institutes of Health 1,003
- 4 Johns Hopkins University 838
- 5 The Ohio State University 807
Cross-Institution Connections
Researchers at different institutions with overlapping expertise in Cancer-Related Molecular Mechanisms Research.