Cancer-Related Molecular Mechanisms Research

770 researchers across 16 institutions

770 Researchers
16 Institutions
62 Grant PIs
134 High Impact

Research in cancer-related molecular mechanisms investigates the fundamental biological processes that drive cancer development, progression, and response to therapy. This work explores how genetic mutations, epigenetic alterations, and changes in cellular signaling pathways contribute to uncontrolled cell growth and metastasis. Investigators utilize a range of molecular biology techniques, including genomics, proteomics, and advanced imaging, to identify novel biomarkers for early detection and therapeutic targets. Studies also examine the complex interplay between cancer cells and their microenvironment, including immune responses and inflammatory processes, to understand how these interactions influence disease outcomes.

This research holds particular relevance for Arkansas, a state facing significant cancer burdens. Understanding the molecular underpinnings of cancer can inform the development of targeted prevention strategies and more effective treatments tailored to the specific needs of the state's population. The work also connects to Arkansas's agricultural and environmental sectors, as studies may investigate potential links between environmental exposures and cancer risk at the molecular level. Furthermore, advancements in this field can contribute to the growth of the state's biotechnology and pharmaceutical industries, fostering economic development through innovation and job creation.

This area of study is inherently interdisciplinary, drawing upon expertise from molecular biology, genetics, pharmacology, immunology, and public health. Researchers across multiple Arkansas institutions collaborate to address complex questions, fostering a broad base of knowledge and engagement within the state. The work directly informs related fields such as disease mechanisms research, cancer treatment and pharmacology, and health disparities research.

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Top Researchers

Name Institution h-index Citations Career Stage Badges
Bart Barlogie UAMS 138 76,058 High Impact
Michael Birrer UAMS 126 103,407 High Impact
Michael J. Birrer UAMS 126 103,407
Jian‐Min Yuan University of Arkansas 100 39,223 High Impact
Guido Tricot UAMS 97 36,236 High Impact
Thomas J. Kelly UAMS 90 29,523 High Impact
John D. Shaughnessy UAMS 88 31,058 High Impact
Edward T.H. Yeh UAMS 87 28,747 High Impact
Weida Tong NCTR 82 29,795
Frits van Rhee UAMS 82 25,962 High Impact
Jingyi Chen University of Arkansas 80 34,318 ARA Grant PI High Impact
Igor P. Pogribny NCTR 75 17,950 ARA High Impact
Thomas M. Badger UAMS 71 15,440 High Impact
Maurizio Zangari UAMS 69 19,177 High Impact
Margaret May UAMS 67 20,743 High Impact
Fenghuang Zhan UAMS 66 19,023 Grant PI High Impact
Shiv Srivastava UAMS 64 15,022 High Impact
Naveena Singh University of Arkansas – Fort Smith 64 16,943 High Impact
Jerry Ware UAMS 60 13,312 High Impact Grants
Luke R. Howard University of Arkansas 58 13,735 High Impact Grants

Connected Research Areas

Topics that share active collaborators with Cancer-Related Molecular Mechanisms Research in Arkansas. Pairs are ranked by collaboration density relative to expected co-authorship under a random null. This describes existing connections, not investment recommendations.

Strategic Outlook

Global signals from OpenAlex for this research area: where the field is growing, how concentrated leadership is, and where Arkansas sits relative to the world's top-100 institutions. Descriptive only — surfaced as input to the conversation about where to place bets, not a recommendation. Signal confidence: LOW

Global trajectory
2 works in 2034
-42.9% CAGR 2018–2034
Leadership concentration
7.4% held by global top 5 institutions
Fragmented HHI 39
Arkansas position
Arkansas not in global top 100
No AR institution among the top-100 contributors to this topic over the 2018–2034 window.

Top US institutions in this area

  1. 1 Harvard University 2,405
  2. 2 The University of Texas MD Anderson Cancer Center 2,085
  3. 3 National Institutes of Health 1,268
  4. 4 Johns Hopkins University 1,259
  5. 5 Stanford University 1,177

Cross-Institution Connections

Researchers at different institutions with overlapping expertise in Cancer-Related Molecular Mechanisms Research.

Colin Furrow University of Arkansas
92%
Jiahui Chen University of Arkansas
92%
Ruizong Li UAMS
80%
Sam Davis Omekara Philander Smith College
79%
Qingfang He UA Little Rock
Colin Furrow University of Arkansas
78%
Jiahui Chen University of Arkansas
78%
Jiahui Chen University of Arkansas
78%
Jiahui Chen University of Arkansas
78%
Jiahui Chen University of Arkansas
78%
Leonard Ferdman Arkansas State University
77%
F. Xia UAMS

Researchers with Federal Grants

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