Cancer-Related Molecular Mechanisms Research
770 researchers across 16 institutions
Research in cancer-related molecular mechanisms investigates the fundamental biological processes that drive cancer development, progression, and response to therapy. This work explores how genetic mutations, epigenetic alterations, and changes in cellular signaling pathways contribute to uncontrolled cell growth and metastasis. Investigators utilize a range of molecular biology techniques, including genomics, proteomics, and advanced imaging, to identify novel biomarkers for early detection and therapeutic targets. Studies also examine the complex interplay between cancer cells and their microenvironment, including immune responses and inflammatory processes, to understand how these interactions influence disease outcomes.
This research holds particular relevance for Arkansas, a state facing significant cancer burdens. Understanding the molecular underpinnings of cancer can inform the development of targeted prevention strategies and more effective treatments tailored to the specific needs of the state's population. The work also connects to Arkansas's agricultural and environmental sectors, as studies may investigate potential links between environmental exposures and cancer risk at the molecular level. Furthermore, advancements in this field can contribute to the growth of the state's biotechnology and pharmaceutical industries, fostering economic development through innovation and job creation.
This area of study is inherently interdisciplinary, drawing upon expertise from molecular biology, genetics, pharmacology, immunology, and public health. Researchers across multiple Arkansas institutions collaborate to address complex questions, fostering a broad base of knowledge and engagement within the state. The work directly informs related fields such as disease mechanisms research, cancer treatment and pharmacology, and health disparities research.
Top Researchers
| Name | Institution | h-index | Citations | Career Stage | Badges |
|---|---|---|---|---|---|
| Bart Barlogie | UAMS | 138 | 76,058 | High Impact | |
| Michael Birrer | UAMS | 126 | 103,407 | High Impact | |
| Michael J. Birrer | UAMS | 126 | 103,407 | ||
| Jian‐Min Yuan | University of Arkansas | 100 | 39,223 | High Impact | |
| Guido Tricot | UAMS | 97 | 36,236 | High Impact | |
| Thomas J. Kelly | UAMS | 90 | 29,523 | High Impact | |
| John D. Shaughnessy | UAMS | 88 | 31,058 | High Impact | |
| Edward T.H. Yeh | UAMS | 87 | 28,747 | High Impact | |
| Weida Tong | NCTR | 82 | 29,795 | ||
| Frits van Rhee | UAMS | 82 | 25,962 | High Impact | |
| Jingyi Chen | University of Arkansas | 80 | 34,318 | ARA Grant PI High Impact | |
| Igor P. Pogribny | NCTR | 75 | 17,950 | ARA High Impact | |
| Thomas M. Badger | UAMS | 71 | 15,440 | High Impact | |
| Maurizio Zangari | UAMS | 69 | 19,177 | High Impact | |
| Margaret May | UAMS | 67 | 20,743 | High Impact | |
| Fenghuang Zhan | UAMS | 66 | 19,023 | Grant PI High Impact | |
| Shiv Srivastava | UAMS | 64 | 15,022 | High Impact | |
| Naveena Singh | University of Arkansas – Fort Smith | 64 | 16,943 | High Impact | |
| Jerry Ware | UAMS | 60 | 13,312 | High Impact Grants | |
| Luke R. Howard | University of Arkansas | 58 | 13,735 | High Impact Grants |
Related Research Areas
Connected Research Areas
Topics that share active collaborators with Cancer-Related Molecular Mechanisms Research in Arkansas. Pairs are ranked by collaboration density relative to expected co-authorship under a random null. This describes existing connections, not investment recommendations.
Strategic Outlook
Global signals from OpenAlex for this research area: where the field is growing, how concentrated leadership is, and where Arkansas sits relative to the world's top-100 institutions. Descriptive only — surfaced as input to the conversation about where to place bets, not a recommendation. Signal confidence: LOW
Top US institutions in this area
- 1 Harvard University 2,405
- 2 The University of Texas MD Anderson Cancer Center 2,085
- 3 National Institutes of Health 1,268
- 4 Johns Hopkins University 1,259
- 5 Stanford University 1,177
Cross-Institution Connections
Researchers at different institutions with overlapping expertise in Cancer-Related Molecular Mechanisms Research.