Mohamed A. Sadek
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Also affiliated: Cairo University (2022–2026); South Valley University (2022–2023)
Research Areas
Biomedical Subjects
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Biography and Research Information
OverviewAI-generated summary
Mohamed A. Sadek's research investigates the neuroprotective and anti-inflammatory effects of various compounds, particularly in the context of autoimmune encephalomyelitis and related neurological conditions. His recent work explores the therapeutic potential of semaglutide, a glucagon-like peptide-1 agonist, in ameliorating experimental autoimmune encephalomyelitis-induced multiple sclerosis in mice, examining its impact on the PI3K/Akt/GSK-3β pathway. Sadek also studies curcumin's neuroprotective role against cognitive and physical impairments in similar mouse models, focusing on the AMPK/SIRT1 pathway. Additionally, his research extends to the development and assessment of novel drug delivery systems, such as terpene-enriched invasomes and capped flexosomes, for enhanced anti-inflammatory and anti-edema activities. He has also investigated PEGylated terpesomes of curcumin for hepatoprotective effects. His earlier work includes contributions to food science, with publications on sesame seed protein concentrates and lipid emulsions.
Metrics
- h-index: 7
- Publications: 14
- Citations: 268
Selected Publications
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Temporal and Age-Dependent Regulation of Phagocytosis-Related Signatures After Ischemic Stroke: Cross-Species Transcriptomic Evidence (2026)
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Morusin as a drug candidate: opportunities, limitations, and the path toward clinical translation (2025)
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A Comprehensive Review on Pulmonary Fibrosis (PF): Histological Spectrum, Diagnosis, Risk Factors, Pathogenesis, Molecular Pathophysiology, and Current Treatment Options (2025)
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Integrative sleep management: from molecular pathways to conventional and herbal treatments (2025)
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Orientin: a comprehensive review of a promising bioactive flavonoid (2025)
Collaboration Network
Top Collaborators
- Orientin: a comprehensive review of a promising bioactive flavonoid
- Integrative sleep management: from molecular pathways to conventional and herbal treatments
- Morusin as a drug candidate: opportunities, limitations, and the path toward clinical translation
- A Comprehensive Review on Pulmonary Fibrosis (PF): Histological Spectrum, Diagnosis, Risk Factors, Pathogenesis, Molecular Pathophysiology, and Current Treatment Options
- Orientin: a comprehensive review of a promising bioactive flavonoid
- Integrative sleep management: from molecular pathways to conventional and herbal treatments
- Morusin as a drug candidate: opportunities, limitations, and the path toward clinical translation
- Orientin: a comprehensive review of a promising bioactive flavonoid
- Morusin as a drug candidate: opportunities, limitations, and the path toward clinical translation
- Integrative sleep management: from molecular pathways to conventional and herbal treatments
- A Comprehensive Review on Pulmonary Fibrosis (PF): Histological Spectrum, Diagnosis, Risk Factors, Pathogenesis, Molecular Pathophysiology, and Current Treatment Options
- Integrative sleep management: from molecular pathways to conventional and herbal treatments
- A Comprehensive Review on Pulmonary Fibrosis (PF): Histological Spectrum, Diagnosis, Risk Factors, Pathogenesis, Molecular Pathophysiology, and Current Treatment Options
- Orientin: a comprehensive review of a promising bioactive flavonoid
- Orientin: a comprehensive review of a promising bioactive flavonoid
- Integrative sleep management: from molecular pathways to conventional and herbal treatments
- Integrative sleep management: from molecular pathways to conventional and herbal treatments
- Integrative sleep management: from molecular pathways to conventional and herbal treatments
- A Comprehensive Review on Pulmonary Fibrosis (PF): Histological Spectrum, Diagnosis, Risk Factors, Pathogenesis, Molecular Pathophysiology, and Current Treatment Options
- A Comprehensive Review on Pulmonary Fibrosis (PF): Histological Spectrum, Diagnosis, Risk Factors, Pathogenesis, Molecular Pathophysiology, and Current Treatment Options
- A Comprehensive Review on Pulmonary Fibrosis (PF): Histological Spectrum, Diagnosis, Risk Factors, Pathogenesis, Molecular Pathophysiology, and Current Treatment Options
- Morusin as a drug candidate: opportunities, limitations, and the path toward clinical translation
- Morusin as a drug candidate: opportunities, limitations, and the path toward clinical translation
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