Shakshi Sharma
Staff Scientist
Also affiliated: Lovely Professional University (2021); Indian Institute of Science Education and Research Mohali (2019); Dr. Yashwant Singh Parmar University of Horticulture and Forestry (2016–2023); University of Arkansas Medical Center (2025); Kanya Maha Vidyalaya (2025); Indo Soviet Friendship College of Pharmacy (2019); Government Ayurvedic College and Hospital (2019–2020); Institute on Aging (2023–2025); Barkatullah University (2018); Punjab Agricultural University (2009)
Geriatrics, College of Medicine
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Shakshi Sharma's research focuses on the molecular mechanisms underlying neurodegenerative diseases and the potential therapeutic roles of natural compounds and nanoparticles. Her work investigates the involvement of mitochondrial dysfunction, oxidative stress, and neuroinflammation in conditions such as Parkinson's disease and traumatic brain injury. Sharma has explored the neuroprotective effects of compounds like quercetin and piperine in animal models, as well as the impact of specific amino acids, such as valine, on mitochondrial function. Her research also extends to the application of bacteriocin-synthesized silver nanoparticles for antimicrobial purposes. Sharma has published over 60 papers, with an h-index of 12 and more than 600 citations. She collaborates extensively with researchers at the University of Arkansas for Medical Sciences, including Gohar Azhar, Jeanne Y. Wei, Pankaj Patyal, and Ambika Verma.
Metrics
- h-index: 12
- Publications: 61
- Citations: 645
Positions
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Staff Scientist 2026–presentArkansas Children's Hospital Clinical research operation ORCID
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Staff Scientist publications 2022–2025University of Arkansas for Medical Sciences Geriatrics, College of Medicine Institutional directory
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Post Doctoral Fellow 2021–2026University of Arkansas for Medical Sciences ORCID
Selected Publications
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Perceptions of Aging in the Hispanic Community Members in South Central United States: A Descriptive and Exploratory Analysis (2026)
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Opinions towards Aging in the Marshallese Community residing in Northwest Arkansas (2025)
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Mitochondrial Dynamics in Aging Heart (2025)
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Alternative Splicing of Serum Response Factor Reveals Isoform-Specific Remodeling in Cardiac Diseases (2025)
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Differential microRNA profiling of the Marshallese population in Arkansas reveals a higher association with chronic diseases (2025)
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Mechanistic insights: How nanoparticles modulate plant hormones and defense response signaling under stress (2025)
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Effect of Protein Supplementation on Orthostatic Hypotension in Older Adult Patients with Heart Failure (2025)
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MONITORING CHRONIC PAIN AND QUALITY OF LIFE USING TABLET SURVEYS IN OLDER ADULTS LIVING IN RURAL ARKANSAS (2024)
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KNOWLEDGE GAPS REGARDING NALOXONE USE AMONG OLDER ADULTS IN HIGH OPIOID PRESCRIBING REGIONS IN SOUTHERN USA (2024)
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DIFFERENTIAL EFFECT OF SIRT1 ON MITOCHONDRIAL FUNCTION: INSIGHTS INTO MITOCHONDRIAL RESPIRATORY COMPLEXES (2024)
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COGNITIVE ASSESSMENT OF MARSHALLESE PEOPLE USING QDRS (QUICK DEMENTIA RATING SCALE) (2024)
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SRF ISOFORMS DIFFERENTIALLY IMPACT MITOCHONDRIAL FUNCTION AND AGING (2024)
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The Role of Sirtuin-1 Isoforms in Regulating Mitochondrial Function (2024)
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Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome (2024)
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Nutritional composition, phytochemical extraction, and pharmacological potential of mulberry: A comprehensive review (2024)
Collaboration Network
Top Collaborators
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Mitochondrial Dynamics in Aging Heart
- The Role of Sirtuin-1 Isoforms in Regulating Mitochondrial Function
- L-VALINE TREATMENT IMPROVES CELLULAR MITOCHONDRIAL FUNCTION
Showing 5 of 22 shared publications
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Mitochondrial Dynamics in Aging Heart
- The Role of Sirtuin-1 Isoforms in Regulating Mitochondrial Function
- L-VALINE TREATMENT IMPROVES CELLULAR MITOCHONDRIAL FUNCTION
Showing 5 of 21 shared publications
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Mitochondrial Dynamics in Aging Heart
- The Role of Sirtuin-1 Isoforms in Regulating Mitochondrial Function
- L-VALINE TREATMENT IMPROVES CELLULAR MITOCHONDRIAL FUNCTION
Showing 5 of 9 shared publications
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Mitochondrial Dynamics in Aging Heart
- The Role of Sirtuin-1 Isoforms in Regulating Mitochondrial Function
- Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome
Showing 5 of 9 shared publications
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Mitochondrial Dynamics in Aging Heart
- The Role of Sirtuin-1 Isoforms in Regulating Mitochondrial Function
- Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome
Showing 5 of 9 shared publications
- Quality Improvement in Delirium Health Literacy in Older Adult Patients and Their Caregivers Attending a Geriatric Clinic
- KNOWLEDGE GAPS REGARDING NALOXONE USE AMONG OLDER ADULTS IN HIGH OPIOID PRESCRIBING REGIONS IN SOUTHERN USA
- A Response to: Quality Improvement in Delirium Health Literacy in Older Adult Patients and Their Caregivers Attending a Geriatric Clinic [Response to Letter]
- MONITORING CHRONIC PAIN AND QUALITY OF LIFE USING TABLET SURVEYS IN OLDER ADULTS LIVING IN RURAL ARKANSAS
- Effect of Protein Supplementation on Orthostatic Hypotension in Older Adult Patients with Heart Failure
Showing 5 of 6 shared publications
- Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome
- Quality Improvement in Delirium Health Literacy in Older Adult Patients and Their Caregivers Attending a Geriatric Clinic
- A Response to: Quality Improvement in Delirium Health Literacy in Older Adult Patients and Their Caregivers Attending a Geriatric Clinic [Response to Letter]
- EVALUATION OF AMINO ACIDS LEVELS OF HOSPITALIZED PATIENTS WITH DELIRIUM
- Effect of Protein Supplementation on Orthostatic Hypotension in Older Adult Patients with Heart Failure
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome
- SIRTUIN 1 ISOFORMS DIFFERENTIALLY IMPACT MITOCHONDRIAL GENE EXPRESSION AND FUNCTION IN MUSCLE CELLS
- KNOWLEDGE GAPS REGARDING NALOXONE USE AMONG OLDER ADULTS IN HIGH OPIOID PRESCRIBING REGIONS IN SOUTHERN USA
- EVALUATION OF AMINO ACIDS LEVELS OF HOSPITALIZED PATIENTS WITH DELIRIUM
- MONITORING CHRONIC PAIN AND QUALITY OF LIFE USING TABLET SURVEYS IN OLDER ADULTS LIVING IN RURAL ARKANSAS
- Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome
- EVALUATION OF AMINO ACIDS LEVELS OF HOSPITALIZED PATIENTS WITH DELIRIUM
- EAAS AND WHEY PROTEIN MAY IMPROVE PHYSICAL FUNCTION OF OLDER ADULTS INDEPENDENTLY OF GUT MICROBIOME
- Mitochondrial Dynamics in Aging Heart
- The Role of Sirtuin-1 Isoforms in Regulating Mitochondrial Function
- DIFFERENTIAL EFFECT OF SIRT1 ON MITOCHONDRIAL FUNCTION: INSIGHTS INTO MITOCHONDRIAL RESPIRATORY COMPLEXES
- Differential microRNA profiling of the Marshallese population in Arkansas reveals a higher association with chronic diseases
- COGNITIVE ASSESSMENT OF MARSHALLESE PEOPLE USING QDRS (QUICK DEMENTIA RATING SCALE)
- Opinions towards Aging in the Marshallese Community residing in Northwest Arkansas
- Differential microRNA profiling of the Marshallese population in Arkansas reveals a higher association with chronic diseases
- COGNITIVE ASSESSMENT OF MARSHALLESE PEOPLE USING QDRS (QUICK DEMENTIA RATING SCALE)
- Opinions towards Aging in the Marshallese Community residing in Northwest Arkansas
- Differential microRNA profiling of the Marshallese population in Arkansas reveals a higher association with chronic diseases
- COGNITIVE ASSESSMENT OF MARSHALLESE PEOPLE USING QDRS (QUICK DEMENTIA RATING SCALE)
- Opinions towards Aging in the Marshallese Community residing in Northwest Arkansas
- A global multicenter propensity-matched analysis of mortality risk and palliative care referral due to cirrhosis in hospitalized patients with COVID-19
- Journal Summary: Hepatitis E Virus Infection after Liver Transplantation
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