Match tier Listed
Presence Current · Arkansas
Last published 2025
Sources OpenAlex · ORCID
Refreshed 2026-08-15

Cam Patterson

High Impact

Researcher

Also affiliated: Bank of America (2015); Rutgers, The State University of New Jersey (2012); University of North Carolina at Chapel Hill (2000–2021); Korea National University of Transportation (2005); North Carolina Central University (2010); Texas Tech University (2003); Brigham and Women's Hospital (1995–2012); Novartis (Switzerland) (2007); Centre National de la Recherche Scientifique (2012); National Institutes of Health (2005); University of North Carolina Health Care (2007–2014); University of Alabama at Birmingham Hospital (2000); Texas Medical Center (1999); NewYork–Presbyterian Hospital (2014–2018); Howard Hughes Medical Institute (2012); University of Wisconsin–Madison (2012); Harvard University (1995–2012); North Carolina State University (2010); Johns Hopkins University (1996–2005); Max Planck Society (2013); Emory University (2011); Université de Bordeaux (2012); Rochester Institute of Technology (2010); University of Freiburg (2005–2012); Chungbuk National University (2005–2017); Montclair State University (2012); Duke University (2004); University of Alabama (2006); German Cancer Research Center (2008); University of California, San Francisco (2012); Baylor College of Medicine (2017); Regeneron (United States) (2007); Vanderbilt University (2000); Cornell University (2006–2018); Heidelberg University (1998–2002); University of Arkansas Medical Center (2018–2023); North Carolina Biotechnology Center (2009); John Sealy Hospital (2000); New York Hospital Queens (2014–2018); University Medical Center Freiburg (2011–2014); Harvard University Press (1995); Johnson University (2012); University of Manchester (2012); Boston Scientific (United States) (2006); University of Alabama at Birmingham (2000); Presbyterian Hospital (2014–2018); Cell Biotech (South Korea) (1998); Xenobe Research Institute (2014); Environmental and Occupational Health Sciences Institute (2012); Diversitech (United States) (2002); Anna Needs Neuroblastoma Answers (2010); University of Education Freiburg (2010); University of North Carolina Hospitals (2014–2015); Cardiovascular Research Center (2003–2009); National Cancer Institute (2002–2006); Mayo Clinic in Florida (2012); Pediatrics and Genetics (2011); Center for Cancer Research (2002–2008); Segeberger Kliniken (2009–2013); Weill Cornell Medical College in Qatar (2017); Hesco (United States) (2012); Harvard Stem Cell Institute (2012); University of North Carolina System (2006); S.P.E.C.I.E.S. (2009); UNC Lineberger Comprehensive Cancer Center (2000–2013); Indiana University School of Medicine (2020–2021); University of Rochester (2010); The University of Texas Medical Branch at Galveston (1997–2014); Rice University (1998); Vanderbilt University Medical Center (2000); McMaster University (1992)

Faculty Researcher

94 h-index 597 pubs 43,136 cited

Upstream record may be merged OpenAlex, the source of these figures, lists 72 institutions in 9 countries for this author record — a pattern that usually means it combines several researchers with similar names. The totals above may include work by other people.

  • Animals
  • Humans
  • Mice
  • Ubiquitin-Protein Ligases
  • Cells, Cultured
  • Signal Transduction
  • Male
  • Proteasome Endopeptidase Complex
  • Mice, Knockout
  • Neovascularization, Physiologic
  • Ubiquitin
  • Rats
  • Mice, Inbred C57BL
  • Female
  • Endothelial Cells

Biography and Research Information

OverviewAI-generated summary

Cam Patterson's research focuses on the molecular mechanisms underlying cellular signaling pathways, particularly those involved in protein degradation and stress responses. His work investigates the role of E3 ubiquitin ligases, such as CHIP (CHIP Is a U-box-dependent E3 Ubiquitin Ligase: IDENTIFICATION OF Hsc70 AS A TARGET FOR UBIQUITYLATION), in targeting proteins for degradation via the proteasome complex. This research has implications for understanding cellular quality control and the impact of protein misfolding and aggregation in various physiological and disease states.

Further investigations delve into the regulation of endothelial function and angiogenesis, exploring how signaling cascades involving factors like IL-28A and AKT promote the formation of new blood vessels (IL-28A/IL-10Rβ axis promotes angiogenesis via eNOS/AKT signaling and AP-1/NF-κB/MMP-2 network by regulating HSP70-1 expression). His studies also examine the interplay between metabolism and immune responses, as seen in research on cholesterol metabolism and its link to cardiac innate immunity (CRAT links cholesterol metabolism to innate immune responses in the heart). Patterson's work also touches on the chaperone-dependent regulation of protein trafficking and function, specifically concerning Hsp70 and its co-chaperone CHIP (Chaperone-dependent Regulation of Endothelial Nitric-oxide Synthase Intracellular Trafficking by the Co-chaperone/Ubiquitin Ligase CHIP).

Metrics

  • h-index: 94
  • Publications: 597
  • Citations: 43,136

Selected Publications

  • IL-28A/IL-10Rβ axis promotes angiogenesis via eNOS/AKT signaling and AP-1/NF-κB/MMP-2 network by regulating HSP70-1 expression (2024)
    7 citations DOI OpenAlex
  • Unique Responsibilities and Challenges of the Lone Academic Medical Center (2024)
    2 citations DOI OpenAlex
  • Design and Impact of a Novel Rural Hospital Alliance (2024)
    3 citations DOI OpenAlex
  • CRAT links cholesterol metabolism to innate immune responses in the heart (2023)
    Nature Metabolism 53 citations DOI OpenAlex
  • Susan S. Smyth (1965–2022) (2023)
  • RESPONSE: Last Fair Deal Gone Down (2022)
  • From Strategic Planning to Strategy Impact (2021)
    4 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

26 Collaborators 11 Institutions 2 Countries

Top Collaborators

View profile →
View profile →

Similar Researchers

Based on overlapping research topics