Disease Mechanisms Research

1028 researchers across 13 institutions

1028 Researchers
13 Institutions
64 Grant PIs
138 High Impact

Researchers investigate the fundamental biological processes that underlie human and animal diseases. This work involves dissecting cellular and molecular pathways to understand how pathogens, genetic mutations, environmental factors, and lifestyle choices disrupt normal physiological function. Studies employ a range of techniques, including genomics, proteomics, microscopy, and advanced computational modeling, to identify disease markers, understand disease progression, and discover potential therapeutic targets. Areas of focus include infectious diseases, cancer, metabolic disorders, neurological conditions, and inflammatory processes.

In Arkansas, this research holds particular relevance for public health initiatives and the state's agricultural economy. Understanding disease mechanisms can inform strategies to combat prevalent health issues within the state's population and protect livestock and crops from infectious agents and environmental toxins. Research into diseases affecting specific demographic groups within Arkansas may also lead to more targeted and effective interventions. Furthermore, advancements in this field can support the growth of the state's biotechnology and pharmaceutical sectors.

This area of study is inherently interdisciplinary, drawing on expertise from molecular biology, immunology, pharmacology, toxicology, and computational science. Engagement spans multiple Arkansas institutions, fostering collaboration across diverse research environments and contributing to a robust statewide research ecosystem.

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Top Researchers

Name Institution h-index Citations Career Stage Badges
Cam Patterson UAMS 94 42,822 High Impact
Thomas J. Kelly UAMS 89 29,180 Faculty High Impact
Stavros C. Manolagas UAMS 85 29,399 Faculty Grant PI High Impact
Edward T.H. Yeh UAMS 85 28,541 ARA High Impact
Andrew Morris UAMS 77 22,261 Faculty Grant PI
Igor P. Pogribny NCTR 76 18,238 ARA High Impact
John D. Imig UAMS 72 16,429 Faculty ARA Grant PI High Impact
Thomas M. Badger UAMS 72 15,745 High Impact
Fenghuang Zhan UAMS 68 19,565 Faculty Grant PI High Impact
W. Sue T. Griffin UAMS 66 17,693 Faculty Grant PI High Impact
Charles A. O’Brien UAMS 64 18,048 Faculty Grant PI High Impact
Jerry Ware UAMS 60 13,312 Faculty High Impact Grants
Laura B. Dunn UAMS 60 13,233 Faculty High Impact
Paula K. Roberson UAMS 58 15,834 Faculty High Impact
Robert L. Jilka UAMS 57 16,846 High Impact
Mark S. Smeltzer UAMS 56 11,340 ARA Grant PI High Impact
Stepan Melnyk UAMS 55 11,039 Faculty High Impact
Maria Almeida UAMS 53 11,869 Faculty Grant PI High Impact
Alan J. Tackett UAMS 52 10,768 ARA Grant PI High Impact
Laura Phillips James UAMS 52 10,522 Faculty ARA Grant PI

Strategic Outlook

Global signals from OpenAlex for this research area: where the field is growing, how concentrated leadership is, and where Arkansas sits relative to the world's top-100 institutions. Descriptive only — surfaced as input to the conversation about where to place bets, not a recommendation. Signal confidence: LOW

Global trajectory
2 works in 2028
-56.8% CAGR 2018–2028
Leadership concentration
7.2% held by global top 5 institutions
Fragmented HHI 37
Arkansas position
Arkansas not in global top 100
No AR institution among the top-100 contributors to this topic over the 2018–2028 window.

Top US institutions in this area

  1. 1 Harvard University 2,463
  2. 2 National Institutes of Health 2,114
  3. 3 University of Pennsylvania 2,080
  4. 4 Johns Hopkins University 1,850
  5. 5 Mayo Clinic in Florida 1,760

Cross-Institution Connections

Researchers at different institutions with overlapping expertise in Disease Mechanisms Research.

100%
Kari Harris Arkansas State University
100%
Fred Limp University of Arkansas
100%
Jenna M. Burchfield University of Arkansas
100%
Kelly Mendes Arkansas State University
100%
K.N. Mitchell University of Arkansas
100%
Genfa Zhou Arkansas State University
100%
Kari Harris Arkansas State University
100%
Fred Limp University of Arkansas
100%
Jenna M. Burchfield University of Arkansas
100%
Kelly Mendes Arkansas State University

Researchers with Federal Grants

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