Alexander Beeser
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Researcher
Faculty Researcher
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Alexander Beeser's research focuses on molecular biology, specifically investigating the function of proteins in biological systems. His work includes mutational analyses of protein domains, such as the cysteine-rich domain of Yvh1, a protein crucial for translational competency in yeast. This research contributes to understanding fundamental biological processes at the molecular level.
Metrics
- h-index: 15
- Publications: 21
- Citations: 2,452
Selected Publications
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Mutational Analyses of the Cysteine-Rich Domain of Yvh1, a Protein Required for Translational Competency in Yeast (2022)
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Overexpression of eIF5 or its protein mimic 5MP perturbs eIF2 function and induces<i>ATF4</i>translation through delayed re-initiation (2016)
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ArhGAP15, a Rac-specific GTPase-activating Protein, Plays a Dual Role in Inhibiting Small GTPase Signaling (2013)
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Emerging Roles of Atypical Dual Specificity Phosphatases in Cancer (2013)
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Characterization of a Human Cell Line Stably Over-Expressing the Candidate Oncogene, Dual Specificity Phosphatase 12 (2011)
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Identification of the Atypical MAPK Erk3 as a Novel Substrate for p21-activated Kinase (Pak) Activity (2011)
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An Isoform-Selective, Small-Molecule Inhibitor Targets the Autoregulatory Mechanism of p21-Activated Kinase (2008)
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Specificity Profiling of Pak Kinases Allows Identification of Novel Phosphorylation Sites (2007)
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The kinase-inhibitory domain of p21-activated kinase 1 (PAK1) inhibits cell cycle progression independent of PAK1 kinase activity (2006)
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Role of Group A p21-activated Kinases in Activation of Extracellular-regulated Kinase by Growth Factors (2005)
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Production and use of a cell permeable inhibitor of group A Paks (TAT-PID) to analyze signal transduction (2005)
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Vav1 Transduces T Cell Receptor Signals to the Activation of the Ras/ERK Pathway via LAT, Sos, and RasGRP1 (2004)
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p21-Activated Kinase 5 (Pak5) Localizes to Mitochondria and Inhibits Apoptosis by Phosphorylating BAD (2003)
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Apoptotic Phosphorylation of Histone H2B Is Mediated by Mammalian Sterile Twenty Kinase (2003)
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Rapid Induction of Dendritic Spine Morphogenesis by trans-Synaptic EphrinB-EphB Receptor Activation of the Rho-GEF Kalirin (2003)
Collaboration Network
Top Collaborators
- Mutational Analyses of the Cysteine-Rich Domain of Yvh1, a Protein Required for Translational Competency in Yeast
- Mutational Analyses of the Cysteine-Rich Domain of Yvh1, a Protein Required for Translational Competency in Yeast
- Mutational Analyses of the Cysteine-Rich Domain of Yvh1, a Protein Required for Translational Competency in Yeast
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