A
Alexis P. Applequist Data-verified
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Researcher
unknown
3 h-index
5 pubs
25 cited
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
Alexis P. Applequist's research investigates the progression of calcific aortic valve disease using a three-dimensional valve-on-chip microphysiological system. This system has implicated cell cycle progression, cholesterol metabolism, and protein homeostasis in the early stages of the disease. Applequist has also developed an in vitro mitral valve model that allows for static trans-mitral pressure studies by utilizing a vacuum to close the valve. Further research includes characterizing piezoelectric-blended polydimethylsiloxane for its potential as a responsive cell culture substrate. Applequist has authored four publications with 22 citations and an h-index of 3. Key collaborators include Kartik Balachandran, Gustavo Vaca-Diez, Ishita Tandon, and Alan E. Woessner, all affiliated with the University of Arkansas at Fayetteville.
Metrics
- h-index: 3
- Publications: 5
- Citations: 25
Selected Publications
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Characterizing Piezoelectric‐Blended Polydimethylsiloxane for Use as a Mechanoelectrical Responsive Cell Culture Substrate (2025)
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A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression (2024)
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In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure (2022)
Collaboration Network
Top Collaborators
Kartik Balachandran
University of Arkansas at Fayetteville
2 shared publications
In database
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
- Characterizing Piezoelectric‐Blended Polydimethylsiloxane for Use as a Mechanoelectrical Responsive Cell Culture Substrate
Sam E. Stephens
University of Arkansas at Fayetteville
1 shared publication
In database
- In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure
Alexander J. Kammien
University of Arkansas at Fayetteville (US)
1 shared publication
- In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure
Jacob C. Paris
University of Arkansas at Fayetteville
1 shared publication
In database
- In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure
Neil B. Ingels
University of Arkansas at Fayetteville
1 shared publication
In database
- In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure
Hanna Jensen
University of Arkansas for Medical Sciences (US)
1 shared publication
- In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure
Drew E. Rodgers
Washington Regional Medical Center (US)
1 shared publication
- In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure
C.R. Cole
Washington Regional Medical Center (US)
1 shared publication
- In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure
Jonathan F. Wenk
University of Kentucky (US)
1 shared publication
- In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure
Morten Ø. Jensen
University of Arkansas at Fayetteville
1 shared publication
In database
- In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure
Ishita Tandon
University of Arkansas at Fayetteville
1 shared publication
In database
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
Alan E. Woessner
University of Arkansas at Fayetteville
1 shared publication
In database
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
Laís Ferreira
University of Arkansas at Fayetteville
1 shared publication
In database
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
Christine Shamblin
Scripps Research Institute (US)
1 shared publication
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
Gustavo Vaca-Diez
University of Arkansas at Fayetteville
1 shared publication
In database
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
Similar Researchers
Based on overlapping research topics
Gustavo Vaca-Diez
University of Arkansas at Fayetteville
Cardiac Valve Diseases and Treatments
Metabolism and Genetic Disorders
Diet and metabolism studies
Denise Fabiano do Nascimento
University of Arkansas at Fayetteville
Metabolism and Genetic Disorders
Tissue Engineering and Regenerative Medicine
Protein Structure and Dynamics
Jason Hoang
University of Arkansas at Fayetteville
Metabolism and Genetic Disorders
Diet and metabolism studies
Protein Structure and Dynamics
Kartik Balachandran
University of Arkansas at Fayetteville
Cardiac Valve Diseases and Treatments
Microfluidic and Bio-sensing Technologies
Tissue Engineering and Regenerative Medicine
Linda G. Jones
University of Arkansas for Medical Sciences
Metabolism and Genetic Disorders
Diet and metabolism studies
Protein Structure and Dynamics
Elizabeth Parish
University of Arkansas at Monticello
Metabolism and Genetic Disorders
Diet and metabolism studies
Cardiovascular Function and Risk Factors