Match tier
Likely match
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-08
A
Alexis P. Applequist
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
Researcher
Unknown Researcher
3 h-index
5 pubs
26 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Alexis P. Applequist investigates the mechanisms underlying calcific aortic valve disease (CAVD) progression using microphysiological systems. Her recent work has focused on developing a three-dimensional valve-on-chip model to study CAVD. This research implicates cell cycle progression, cholesterol metabolism, and protein homeostasis in the early stages of the disease. Applequist also developed an in vitro mitral valve model that allows for unrestricted ventricular access, employing vacuum to facilitate valve closure and enable static trans-mitral pressure measurements. Additionally, her research includes characterizing piezoelectric-blended polydimethylsiloxane for its potential use as a cell culture substrate responsive to mechanical stimuli. Applequist has published five papers with 26 citations and an h-index of 3. She collaborates with Kartik Balachandran, Gustavo Vaca-Diez, Ishita Tandon, and Alan E. Woessner, all at the University of Arkansas at Fayetteville.
Metrics
- h-index: 3
- Publications: 5
- Citations: 26
Selected Publications
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Characterization of Human Aortic Valve Cells isolated from Calcified Aortic Valve Replacement Explants: Implications for Calcific Aortic Valve Disease Research (2026)
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Characterizing Piezoelectric‐Blended Polydimethylsiloxane for Use as a Mechanoelectrical Responsive Cell Culture Substrate (2025)
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A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression (2024)
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In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure (2022)
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Self-Powered Cardiac Pacemaker: The Viability of a Piezoelectric Energy Harvester (2020)
Collaboration Network
Top Collaborators
Kartik Balachandran
University of Arkansas at Fayetteville
2 shared publications
In database
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
- Characterizing Piezoelectric‐Blended Polydimethylsiloxane for Use as a Mechanoelectrical Responsive Cell Culture Substrate
Sam E. Stephens
University of Arkansas at Fayetteville
1 shared publication
In database
- In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure
Alexander J. Kammien
University of Arkansas at Fayetteville (US)
1 shared publication
- In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure
Jacob C. Paris
University of Arkansas at Fayetteville
1 shared publication
In database
- In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure
Neil B. Ingels
University of Arkansas at Fayetteville
1 shared publication
In database
- In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure
Hanna Jensen
University of Arkansas for Medical Sciences
1 shared publication
In database
- In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure
Drew E. Rodgers
Washington Regional Medical Center (US)
1 shared publication
- In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure
C.R. Cole
Washington Regional Medical Center (US)
1 shared publication
- In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure
Jonathan F. Wenk
University of Kentucky (US)
1 shared publication
- In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure
Morten Ø. Jensen
University of Arkansas at Fayetteville
1 shared publication
In database
- In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure
Ishita Tandon
University of Arkansas at Fayetteville
1 shared publication
In database
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
Alan E. Woessner
University of Arkansas at Fayetteville
1 shared publication
In database
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
Laís Ferreira
University of Arkansas at Fayetteville
1 shared publication
In database
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
Christine Shamblin
Scripps Research Institute (US)
1 shared publication
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
Gustavo Vaca-Diez
University of Arkansas at Fayetteville
1 shared publication
In database
- A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression
Similar Researchers
Based on overlapping research topics
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