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Biography and Research Information
OverviewAI-generated summary
Cam Patterson's research program focuses on understanding the molecular mechanisms that regulate cellular processes, particularly those involved in protein homeostasis and cardiovascular function. His work has investigated the role of E3 ubiquitin ligases, such as CHIP (Coiled-coil protein containing a high mobility group box 1 protein), in targeting proteins for degradation via the ubiquitin-proteasome system. This includes studies on how chaperones, like Hsc70, interact with CHIP to regulate the ubiquitylation of specific protein substrates, impacting cellular protein quality control.
Further investigations by Patterson's lab have explored the connection between cholesterol metabolism and innate immune responses in the heart, as well as the signaling pathways that promote angiogenesis, the formation of new blood vessels. His publications also touch upon the origins of circulation and the development of the vascular system. Collaborations with researchers at the University of Arkansas for Medical Sciences, including Kristie Hadden and Stephanie M. Gardner, have contributed to his publication record.
Patterson is recognized as a highly cited researcher, with a h-index of 93 and over 42,000 citations across nearly 600 publications. His active research lab maintains a website detailing ongoing projects and findings.
Metrics
- h-index: 94
- Publications: 599
- Citations: 42,707
Selected Publications
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IL-28A/IL-10Rβ axis promotes angiogenesis via eNOS/AKT signaling and AP-1/NF-κB/MMP-2 network by regulating HSP70-1 expression (2024)
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Unique Responsibilities and Challenges of the Lone Academic Medical Center (2024)
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Design and Impact of a Novel Rural Hospital Alliance (2024)
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CRAT links cholesterol metabolism to innate immune responses in the heart (2023)
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Susan S. Smyth (1965–2022) (2023)
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RESPONSE: Last Fair Deal Gone Down (2022)
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From Strategic Planning to Strategy Impact (2021)
Collaboration Network
Top Collaborators
- The Role of Calcineurin/NFAT in SFRP2 Induced Angiogenesis—A Rationale for Breast Cancer Treatment with the Calcineurin Inhibitor Tacrolimus
- Supplementary Figure and Methods from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Gene List from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Data from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Gene List from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
Showing 5 of 19 shared publications
- The Role of Calcineurin/NFAT in SFRP2 Induced Angiogenesis—A Rationale for Breast Cancer Treatment with the Calcineurin Inhibitor Tacrolimus
- Supplementary Figure and Methods from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Gene List from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Data from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Gene List from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
Showing 5 of 19 shared publications
- The Role of Calcineurin/NFAT in SFRP2 Induced Angiogenesis—A Rationale for Breast Cancer Treatment with the Calcineurin Inhibitor Tacrolimus
- Supplementary Figure 2 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 3 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 1 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 1 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
Showing 5 of 13 shared publications
- The Role of Calcineurin/NFAT in SFRP2 Induced Angiogenesis—A Rationale for Breast Cancer Treatment with the Calcineurin Inhibitor Tacrolimus
- Supplementary Figure 2 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 3 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 1 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 1 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
Showing 5 of 13 shared publications
- Regulation of the Cytoplasmic Quality Control Protein Degradation Pathway by BAG2
- Supplementary Figure and Methods from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Gene List from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Data from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Gene List from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
Showing 5 of 7 shared publications
- Regression of pressure-induced left ventricular hypertrophy is characterized by a distinct gene expression profile
- Supplementary Figure and Methods from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Gene List from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Data from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Gene List from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
Showing 5 of 7 shared publications
- The Role of Calcineurin/NFAT in SFRP2 Induced Angiogenesis—A Rationale for Breast Cancer Treatment with the Calcineurin Inhibitor Tacrolimus
- Supplementary Figure 2 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 3 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 1 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 1 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
Showing 5 of 7 shared publications
- The Role of Calcineurin/NFAT in SFRP2 Induced Angiogenesis—A Rationale for Breast Cancer Treatment with the Calcineurin Inhibitor Tacrolimus
- Supplementary Figure 2 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 3 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 1 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 1 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
Showing 5 of 7 shared publications
- Supplementary Figure and Methods from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Gene List from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Data from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Gene List from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Figure and Methods from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
Showing 5 of 6 shared publications
- Supplementary Figure and Methods from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Gene List from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Data from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Gene List from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Figure and Methods from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
Showing 5 of 6 shared publications
- Supplementary Figure and Methods from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Gene List from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Data from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Gene List from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Figure and Methods from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
Showing 5 of 6 shared publications
- Supplementary Figure and Methods from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Gene List from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Data from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Gene List from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Figure and Methods from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
Showing 5 of 6 shared publications
- Supplementary Figure and Methods from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Gene List from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Data from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Gene List from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
- Supplementary Figure and Methods from 2-Methoxyestradiol Inhibits the Anaphase-Promoting Complex and Protein Translation in Human Breast Cancer Cells
Showing 5 of 6 shared publications
- Supplementary Figure 2 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 3 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 1 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 1 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 2 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
Showing 5 of 6 shared publications
- Supplementary Figure 2 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 3 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 1 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 1 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
- Supplementary Figure 2 from Secreted Frizzle-Related Protein 2 Stimulates Angiogenesis via a Calcineurin/NFAT Signaling Pathway
Showing 5 of 6 shared publications
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