Charles Dumontet

High Impact

Professor

Lyon College

faculty

79 h-index 711 pubs 29,982 cited

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Biography and Research Information

OverviewAI-generated summary

Professor Charles Dumontet's research encompasses a range of topics in cancer biology and treatment, with a strong emphasis on hematological malignancies. His work spans from the molecular characterization of myeloma to the development of novel therapeutic strategies for leukemia and lymphoma. He is particularly interested in antibody-based therapies, as evidenced by his publications on antibody-drug conjugates (ADCs) and their applications in oncology. Recent work has explored payload diversification strategies for ADCs and the development of exatecan-based ADCs using polysarcosine drug-linker platforms. Dumontet also investigates the evolutionary pathways leading to multiple myeloma and mechanisms of resistance to anti-PD-1/PD-L1 therapies.

His primary research interests include multiple myeloma, chronic lymphocytic leukemia, monoclonal and polyclonal antibodies, microtubule and mitosis dynamics, and lymphoma diagnosis and treatment.

Metrics

  • h-index: 79
  • Publications: 711
  • Citations: 29,982

Selected Publications

  • Targeting glutaminase to starve lymphoma cells (2022) DOI
  • A pleiotropic variant in <scp><i>DNAJB4</i></scp> is associated with multiple myeloma risk (2022) DOI

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