Daniel J. Lessner
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Professor
Also affiliated: University of Iowa (2000–2005); Pennsylvania State University (2005–2010)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Daniel J. Lessner's research investigates microbial metabolism and the molecular mechanisms underlying biological processes. His work has explored the enzymatic pathways involved in the oxidation of aromatic compounds, such as naphthalene and nitrobenzene, examining the role of specific amino acids in enzyme activity and substrate specificity. Lessner has also studied methanogenesis, particularly the conversion of acetate to methane in marine archaea like *Methanosarcina acetivorans*, and has investigated unconventional pathways for carbon dioxide reduction to methane in these organisms. His research has also touched upon the oxidant tolerance of *Methanosarcina acetivorans*. Lessner has published 38 papers, which have been cited over 1,355 times, and holds an h-index of 17. He has collaborated with researchers at the University of Arkansas at Fayetteville, including Melissa Chanderban, Thomas M. Deere, Diego Della Lunga, and Kristofor R. Brye.
Metrics
- h-index: 17
- Publications: 38
- Citations: 1,357
Positions
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Professor 2014–presentUniversity of Arkansas Department of Biological Sciences ORCID
Selected Publications
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Cryo-EM structure of a methanogen nitrogenase-PII protein supercomplex (2025)
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ModE Regulates Alternative Nitrogenase Expression in the Methanogen Methanosarcina acetivorans (2025)
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Water regime and fertilizer‐phosphorus source effects on greenhouse gas emissions from rice (2024)
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Struvite-phosphorus effects on greenhouse gas emissions and plant and soil response in a furrow-irrigated rice production system in eastern Arkansas (2024)
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The nitrogenase cofactor biogenesis enzyme NifB is essential for the viability of methanogens (2023)
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The minimal SUF system is not required for Fe–S cluster biogenesis in the methanogenic archaeon Methanosarcina acetivorans (2023)
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Expression of V-nitrogenase and Fe-nitrogenase in Methanosarcina acetivorans is controlled by molybdenum, fixed nitrogen, and the expression of Mo-nitrogenase (2023)
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The minimal SUF system is not required for Fe-S cluster biogenesis in the methanogenic archaeon Methanosarcina acetivorans (2023)
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Struvite Effects on Rice Growth and Productivity under Flood-Irrigation in the Greenhouse (2023)
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Methanosarcina acetivorans (2022)
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Site position and tillage treatment effects on nitrous oxide emissions from furrow-irrigated rice on a silt-loam Alfisol in the Mid-south, USA (2022)
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Vht hydrogenase is required for hydrogen cycling during nitrogen fixation by the non-hydrogenotrophic methanogen Methanosarcina acetivorans (2021)
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Methanosarcina acetivorans simultaneously produces molybdenum, vanadium, and iron-only nitrogenases in response to fixed nitrogen and molybdenum depletion (2021)
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Methanosarcina acetivorans contains a functional ISC system for iron-sulfur cluster biogenesis (2020)
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A CRISPRi-dCas9 System for Archaea and Its Use To Examine Gene Function during Nitrogen Fixation by Methanosarcina acetivorans (2020)
Collaboration Network
Top Collaborators
- A CRISPRi-dCas9 System for Archaea and Its Use To Examine Gene Function during Nitrogen Fixation by Methanosarcina acetivorans
- Expression of V-nitrogenase and Fe-nitrogenase in Methanosarcina acetivorans is controlled by molybdenum, fixed nitrogen, and the expression of Mo-nitrogenase
- A CRISPRi-dCas9 system for archaea and its use to examine gene function during nitrogen fixation by Methanosarcina acetivorans
- The nitrogenase cofactor biogenesis enzyme NifB is essential for the viability of methanogens
- Methanosarcina acetivorans simultaneously produces molybdenum, vanadium, and iron-only nitrogenases in response to fixed nitrogen and molybdenum depletion
Showing 5 of 6 shared publications
- Methanosarcina acetivorans contains a functional ISC system for iron-sulfur cluster biogenesis
- The minimal SUF system is not required for Fe–S cluster biogenesis in the methanogenic archaeon Methanosarcina acetivorans
- Methanosarcina acetivorans
- Cryo-EM structure of a methanogen nitrogenase-PII protein supercomplex
- Vht hydrogenase is required for hydrogen cycling during nitrogen fixation by the non-hydrogenotrophic methanogen Methanosarcina acetivorans
Showing 5 of 6 shared publications
- Expression of V-nitrogenase and Fe-nitrogenase in Methanosarcina acetivorans is controlled by molybdenum, fixed nitrogen, and the expression of Mo-nitrogenase
- Methanosarcina acetivorans
- Cryo-EM structure of a methanogen nitrogenase-PII protein supercomplex
- Methanosarcina acetivorans simultaneously produces molybdenum, vanadium, and iron-only nitrogenases in response to fixed nitrogen and molybdenum depletion
- Vht hydrogenase is required for hydrogen cycling during nitrogen fixation by the non-hydrogenotrophic methanogen Methanosarcina acetivorans
Showing 5 of 6 shared publications
- Expression of a bacterial catalase in a strictly anaerobic methanogen significantly increases tolerance to hydrogen peroxide but not oxygen
- Subunit D of RNA Polymerase from Methanosarcina acetivorans Contains Two Oxygen-labile [4Fe-4S] Clusters
- Methanosarcina acetivorans contains a functional ISC system for iron-sulfur cluster biogenesis
- Methanosarcina acetivorans utilizes a single NADPH-dependent thioredoxin system and contains additional thioredoxin homologues with distinct functions
- The [4Fe‐4S] clusters of Rpo3 are key determinants in the post Rpo3/Rpo11 heterodimer formation of RNA polymerase in Methanosarcina acetivorans
- Molecular characterization of the thioredoxin system from M ethanosarcina acetivorans
- The Methanosarcina acetivorans thioredoxin system activates DNA binding of the redox-sensitive transcriptional regulator MsvR
- Methanosarcina acetivorans utilizes a single NADPH-dependent thioredoxin system and contains additional thioredoxin homologues with distinct functions
- Toward a mechanistic and physiological understanding of a ferredoxin:disulfide reductase from the domains Archaea and Bacteria
- Site position and tillage treatment effects on nitrous oxide emissions from furrow-irrigated rice on a silt-loam Alfisol in the Mid-south, USA
- Struvite Effects on Rice Growth and Productivity under Flood-Irrigation in the Greenhouse
- Struvite-phosphorus effects on greenhouse gas emissions and plant and soil response in a furrow-irrigated rice production system in eastern Arkansas
- Water regime and fertilizer‐phosphorus source effects on greenhouse gas emissions from rice
- Site position and tillage treatment effects on nitrous oxide emissions from furrow-irrigated rice on a silt-loam Alfisol in the Mid-south, USA
- Struvite Effects on Rice Growth and Productivity under Flood-Irrigation in the Greenhouse
- Struvite-phosphorus effects on greenhouse gas emissions and plant and soil response in a furrow-irrigated rice production system in eastern Arkansas
- Water regime and fertilizer‐phosphorus source effects on greenhouse gas emissions from rice
- The minimal SUF system is not required for Fe–S cluster biogenesis in the methanogenic archaeon Methanosarcina acetivorans
- Methanosarcina acetivorans
- The nitrogenase cofactor biogenesis enzyme NifB is essential for the viability of methanogens
- The minimal SUF system is not required for Fe-S cluster biogenesis in the methanogenic archaeon Methanosarcina acetivorans
- The Methanosarcina acetivorans thioredoxin system activates DNA binding of the redox-sensitive transcriptional regulator MsvR
- Redox-sensitive DNA binding by homodimeric Methanosarcina acetivorans MsvR is modulated by cysteine residues
- The [4Fe‐4S] clusters of Rpo3 are key determinants in the post Rpo3/Rpo11 heterodimer formation of RNA polymerase in Methanosarcina acetivorans
- Expression of a bacterial catalase in a strictly anaerobic methanogen significantly increases tolerance to hydrogen peroxide but not oxygen
- Subunit D of RNA Polymerase from Methanosarcina acetivorans Contains Two Oxygen-labile [4Fe-4S] Clusters
- The [4Fe‐4S] clusters of Rpo3 are key determinants in the post Rpo3/Rpo11 heterodimer formation of RNA polymerase in Methanosarcina acetivorans
- Site position and tillage treatment effects on nitrous oxide emissions from furrow-irrigated rice on a silt-loam Alfisol in the Mid-south, USA
- Struvite-phosphorus effects on greenhouse gas emissions and plant and soil response in a furrow-irrigated rice production system in eastern Arkansas
- Water regime and fertilizer‐phosphorus source effects on greenhouse gas emissions from rice
- Struvite Effects on Rice Growth and Productivity under Flood-Irrigation in the Greenhouse
- Struvite-phosphorus effects on greenhouse gas emissions and plant and soil response in a furrow-irrigated rice production system in eastern Arkansas
- Water regime and fertilizer‐phosphorus source effects on greenhouse gas emissions from rice
- Struvite Effects on Rice Growth and Productivity under Flood-Irrigation in the Greenhouse
- Struvite-phosphorus effects on greenhouse gas emissions and plant and soil response in a furrow-irrigated rice production system in eastern Arkansas
- Water regime and fertilizer‐phosphorus source effects on greenhouse gas emissions from rice
- Assessment of the oxidant tolerance ofMethanosarcina acetivorans
- Expression of a bacterial catalase in a strictly anaerobic methanogen significantly increases tolerance to hydrogen peroxide but not oxygen
- The Methanosarcina acetivorans thioredoxin system activates DNA binding of the redox-sensitive transcriptional regulator MsvR
- Redox-sensitive DNA binding by homodimeric Methanosarcina acetivorans MsvR is modulated by cysteine residues
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