Biography and Research Information
OverviewAI-generated summary
Daniel W. Armstrong's research program focuses on the development and application of advanced analytical separation science techniques. He has published extensively on stereoisomerism, particularly in the context of disease biomarkers, and has investigated the use of metal-organic frameworks and cyclodextrins in separation processes. His work also explores the role of D-amino acids in biological systems and advances in chiral crystallization. Armstrong has a significant publication record, with 829 total publications and 39,657 citations, reflected in his h-index of 98, designating him as a highly cited researcher.
His recent work includes publications on the detection and analysis of chiral molecules as disease biomarkers, the application of metal-organic frameworks in separations, and the study of D-amino acids in biological systems. He has also explored enantioselective UHPLC screening combined with in silico modeling for ultrafast enantiopurity assays and reviewed recent advances in chiral crystallization. Further contributions include work on arsenic sequestration by iron oxide coated geopolymer microspheres and the development of mirror-image cyclodextrins.
Armstrong collaborates with researchers at the University of Arkansas for Medical Sciences, including Brendan Frett, Baku Acharya, Baha’a Jabali, and Alan Herrera-Rueda, with whom he shares multiple publications. His recent activity indicates an ongoing engagement with his research areas.
Metrics
- h-index: 98
- Publications: 829
- Citations: 39,657
Selected Publications
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Kinase inhibitor macrocycles: a perspective on limiting conformational flexibility when targeting the kinome with small molecules (2023)
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FLT3 inhibitors for acute myeloid leukemia: successes, defeats, and emerging paradigms (2022)
Collaboration Network
Top Collaborators
- An examination of the effects of water on normal phase enantioseparations
- Optimization of analytical method greenness scores: a case study of amino acid enantioseparations with carbonated aqueous systems
- High efficiency functionalized hydrophilic cyclofructans as stationary phases in sub/supercritical fluid chromatography
- Automated Regularized Deconvolution for Eliminating Extra-Column Effects in Fast High-Efficiency Separations
- Symmetrization of Peaks in Chiral Chromatography with an Area-Invariant Resolution Enhancement Method
Showing 5 of 10 shared publications
- Mirror-image cyclodextrins
- High information spectroscopic detection techniques for gas chromatography
- Evaluation of gas chromatography for the separation of a broad range of isotopic compounds
- An examination of the effects of water on normal phase enantioseparations
- Effect of position of deuterium atoms on gas chromatographic isotope effects
Showing 5 of 9 shared publications
- Optimization of analytical method greenness scores: a case study of amino acid enantioseparations with carbonated aqueous systems
- Automated Regularized Deconvolution for Eliminating Extra-Column Effects in Fast High-Efficiency Separations
- Strategies and considerations to green analytical separations: a review
- Symmetrization of Peaks in Chiral Chromatography with an Area-Invariant Resolution Enhancement Method
- Insights into enantioselective separations of ionic metal complexes by sub/supercritical fluid chromatography
Showing 5 of 7 shared publications
- Occurrence of D-amino acids in natural products
- An examination of the effects of water on normal phase enantioseparations
- A Closer Examination of 6-Aminoquinolyl-N-Hydroxysuccinimidyl Carbamate Amino Acid Derivatization in HPLC with Multiple Detection Modes
- Enantiomeric Separation of New Chiral Azole Compounds
- Comparison of core‐shell versus fully porous particle packings for chiral liquid chromatography productivity
Showing 5 of 6 shared publications
- A Closer Examination of 6-Aminoquinolyl-N-Hydroxysuccinimidyl Carbamate Amino Acid Derivatization in HPLC with Multiple Detection Modes
- Enhanced carboxypeptidase efficacies and differentiation of peptide epimers
- Comprehensive chiral GC-MS/MS and LC-MS/MS methods for identification and determination of N-acyl homoserine lactones
- Teicoplanin aglycone media and carboxypeptidase Y: Tools for finding low‐abundance D‐amino acids and epimeric peptides
- Unusual enantiomeric D,L-N-acyl homoserine lactones in Pectobacterium atrosepticum and Pseudomonas aeruginosa
- Recent advances in the field of chiral crystallization
- Enantiomeric Separation of New Chiral Azole Compounds
- Enhanced carboxypeptidase efficacies and differentiation of peptide epimers
- Antibody binding of amyloid beta peptide epimers/isomers and ramifications for immunotherapies and drug development
- Metal-organic frameworks in separations: A review
- High efficiency functionalized hydrophilic cyclofructans as stationary phases in sub/supercritical fluid chromatography
- Ionizable Cyclofructan 6-Based Stationary Phases for Hydrophilic Interaction Liquid Chromatography Using Superficially Porous Particles
- A Metal Organic Framework + Ionic Liquid Pseudophase System as a Gas Chromatography Stationary Phase
- Production of both <scp>l</scp>‐ and <scp>d</scp>‐ <i>N</i>‐acyl‐homoserine lactones by <i>Burkholderia cepacia</i> and <i>Vibrio fischeri</i>
- Rapid and selective separation of amyloid beta from its stereoisomeric point mutations implicated in neurodegenerative Alzheimer’s disease
- Comprehensive chiral GC-MS/MS and LC-MS/MS methods for identification and determination of N-acyl homoserine lactones
- Antibody binding of amyloid beta peptide epimers/isomers and ramifications for immunotherapies and drug development
- High efficiency functionalized hydrophilic cyclofructans as stationary phases in sub/supercritical fluid chromatography
- Chiral resolution and absolute configuration determination of new metal-based photodynamic therapy antitumor agents
- Ionizable Cyclofructan 6-Based Stationary Phases for Hydrophilic Interaction Liquid Chromatography Using Superficially Porous Particles
- <scp>d</scp>‐Amino acids in biological systems
- Rapid and selective separation of amyloid beta from its stereoisomeric point mutations implicated in neurodegenerative Alzheimer’s disease
- Ionizable Cyclofructan 6-Based Stationary Phases for Hydrophilic Interaction Liquid Chromatography Using Superficially Porous Particles
- Chiral resolution and absolute configuration determination of new metal-based photodynamic therapy antitumor agents
- Focusing on C-4 position of Hantzsch 1,4-dihydropyridines: Molecular modifications, enantioseparation, and binding mechanism to L- and T-type calcium channels
- Actions and Interactions of Mirror-Image Cyclodextrins
- Enantioseparation of ß-amino acids by liquid chromatography using core-shell chiral stationary phases based on teicoplanin and teicoplanin aglycone
- Macrocyclic glycopeptides- and derivatized cyclofructan-based chiral stationary phases for the enantioseparation of fluorinated ß-phenylalanine analogs
- Enantioseparation of a-substituted proline analogs with macrocyclic glycopeptide-based chiral stationary phases immobilized on superficially porous particles of silica applying liquid chromatography with ultraviolet and mass spectrometric detection
- Enantioseparation of ß-amino acids by liquid chromatography using core-shell chiral stationary phases based on teicoplanin and teicoplanin aglycone
- Macrocyclic glycopeptides- and derivatized cyclofructan-based chiral stationary phases for the enantioseparation of fluorinated ß-phenylalanine analogs
- Enantioseparation of a-substituted proline analogs with macrocyclic glycopeptide-based chiral stationary phases immobilized on superficially porous particles of silica applying liquid chromatography with ultraviolet and mass spectrometric detection
- Enantioseparation of ß-amino acids by liquid chromatography using core-shell chiral stationary phases based on teicoplanin and teicoplanin aglycone
- Macrocyclic glycopeptides- and derivatized cyclofructan-based chiral stationary phases for the enantioseparation of fluorinated ß-phenylalanine analogs
- Enantioseparation of a-substituted proline analogs with macrocyclic glycopeptide-based chiral stationary phases immobilized on superficially porous particles of silica applying liquid chromatography with ultraviolet and mass spectrometric detection
- Enantioseparation of ß-amino acids by liquid chromatography using core-shell chiral stationary phases based on teicoplanin and teicoplanin aglycone
- Macrocyclic glycopeptides- and derivatized cyclofructan-based chiral stationary phases for the enantioseparation of fluorinated ß-phenylalanine analogs
- Enantioseparation of a-substituted proline analogs with macrocyclic glycopeptide-based chiral stationary phases immobilized on superficially porous particles of silica applying liquid chromatography with ultraviolet and mass spectrometric detection
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