Emily Hopewell Source Confirmed
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Researcher
John Brown University
faculty
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Biography and Research Information
OverviewAI-generated summary
Dr. Emily Hopewell is engaged in groundbreaking research at John Brown University, focusing on the innovative realm of CAR-T cell therapy and its application in treating hematologic malignancies. Her work extends to the broader fields of immunotherapy and immune responses, as evidenced by recent publications exploring the feasibility and tolerability of CD4-directed CAR-T cell therapy in initial human trials. Hopewell's investigations also delve into the complexities of immune cell function and interaction, including strategies for reprogramming intratumoral T<sub>reg</sub> cells to enhance cancer immunotherapy. Furthermore, she is actively involved in optimizing the expansion of natural killer cells for adoptive immunotherapy trials, employing advanced bioreactor technology. Her research encompasses NF-κB signaling pathways and the intricate interplay between immune response and inflammation.
Metrics
- h-index: 8
- Publications: 24
- Citations: 482
Selected Publications
- 358 Efficient expansion of clinical-grade nature killer cells using the G-rex bioreactor for adoptive immunotherapy trials (2025) DOI
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