Biography and Research Information
OverviewAI-generated summary
Jai Shankar K. Yadlapalli's research focuses on the pharmacological effects of opioid analgesics, particularly morphine derivatives, in preclinical models. His work has investigated the pharmacokinetics of morphine-6-O-sulfate in rat plasma and brain tissue. This research contributes to understanding drug distribution and metabolism within the central nervous system. Yadlapalli has published 18 papers, accumulating 151 citations, and holds an h-index of 6. His collaborations include shared publications with researchers such as Narsimha Reddy Penthala, Philip J. Breen, Peter A. Crooks, and Zaineb A.F. Albayati, all from the University of Arkansas for Medical Sciences. His recent publication in 2021 indicates continued activity in this research area.
Metrics
- h-index: 6
- Publications: 18
- Citations: 157
Selected Publications
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A pharmacokinetic study of <scp>morphine‐6‐<i>O</i></scp>‐sulfate in rat plasma and brain (2021)
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Evaluation of morphine‐like effects of the mixed mu/delta agonist morphine‐6‐<i>O</i>‐sulfate in rats: Drug discrimination and physical dependence (2018)
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Pinprick hypo- and hyperalgesia in diabetic rats: Can diet content affect experimental outcome? (2018)
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Preclinical assessment of utility of M6S for multimodal acute and chronic pain treatment in diabetic neuropathy (2017)
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Evaluation of Analgesia, Tolerance, and the Mechanism of Action of Morphine-6-O-Sulfate Across Multiple Pain Modalities in Sprague-Dawley Rats (2017)
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Stability studies of potent opioid analgesic, morphine‐6‐<i>O‐</i>sulfate in various buffers and biological matrices by HPLC‐DAD analysis (2017)
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X‐irradiation and Simulated Microgravity affects Rat Weight, Food Intake, Insulin and Paw Pressure Pain Threshold (2016)
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Antinociceptive effects of the 6- O -sulfate ester of morphine in normal and diabetic rats: Comparative role of mu- and delta-opioid receptors (2016)
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Degenerative Tissue Responses to Space-like Radiation Doses in a Rodent Model of Simulated Microgravity. (2016)
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Crystal structures of (<i>Z</i>)-5-[2-(benzo[<i>b</i>]thiophen-2-yl)-1-(3,5-dimethoxyphenyl)ethenyl]-1<i>H</i>-tetrazole and (<i>Z</i>)-5-[2-(benzo[<i>b</i>]thiophen-3-yl)-1-(3,4,5-trimethoxyphenyl)ethenyl]-1<i>H</i>-tetrazole (2016)
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A novel and efficient tributyltin azide-mediated synthesis of 1H-tetrazolylstilbenes from cyanostilbenes (2016)
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(434) Analgesic profile of morphine 6-O-sulfate sodium: a mixed mu/delta agonist in the treatment of diabetic neuropathic pain (2015)
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Synthesis and evaluation of a series of benzothiophene acrylonitrile analogs as anticancer agents (2013)
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Seeking Predictable Subject Characteristics That Influence Clinical Trial Discontinuation (2012)
Collaboration Network
Top Collaborators
- A pharmacokinetic study of <scp>morphine‐6‐<i>O</i></scp>‐sulfate in rat plasma and brain
- A pharmacokinetic study of <scp>morphine‐6‐<i>O</i></scp>‐sulfate in rat plasma and brain
- A pharmacokinetic study of <scp>morphine‐6‐<i>O</i></scp>‐sulfate in rat plasma and brain
- A pharmacokinetic study of <scp>morphine‐6‐<i>O</i></scp>‐sulfate in rat plasma and brain
- A pharmacokinetic study of <scp>morphine‐6‐<i>O</i></scp>‐sulfate in rat plasma and brain
- A pharmacokinetic study of <scp>morphine‐6‐<i>O</i></scp>‐sulfate in rat plasma and brain
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