Match tier
Listed
Presence
Current · Arkansas
Last published
2021
Sources
OpenAlex · ORCID
Refreshed
2026-10-05
Biography and Research Information
OverviewAI-generated summary
Jai Shankar K. Yadlapalli's research focuses on the pharmacological effects of opioid analgesics, particularly morphine derivatives, in preclinical models. His work has investigated the pharmacokinetics of morphine-6-O-sulfate in rat plasma and brain tissue. This research contributes to understanding drug distribution and metabolism within the central nervous system. Yadlapalli has published 18 papers, accumulating 151 citations, and holds an h-index of 6. His collaborations include shared publications with researchers such as Narsimha Reddy Penthala, Philip J. Breen, Peter A. Crooks, and Zaineb A.F. Albayati, all from the University of Arkansas for Medical Sciences. His recent publication in 2021 indicates continued activity in this research area.
Metrics
- h-index: 6
- Publications: 18
- Citations: 161
Positions
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Senior Scientist 2019–presentJohnson Matthey Analytical Research and Development ORCID
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Senior Scientist publications 2012–2021University of Arkansas for Medical Sciences ORCID
Selected Publications
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A pharmacokinetic study of morphine‐6‐O ‐sulfate in rat plasma and brain (2021)
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Evaluation of morphine‐like effects of the mixed mu/delta agonist morphine‐6‐O‐sulfate in rats: Drug discrimination and physical dependence (2018)
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Pinprick hypo- and hyperalgesia in diabetic rats: Can diet content affect experimental outcome? (2018)
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Preclinical assessment of utility of M6S for multimodal acute and chronic pain treatment in diabetic neuropathy (2017)
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Evaluation of Analgesia, Tolerance, and the Mechanism of Action of Morphine-6-O-Sulfate Across Multiple Pain Modalities in Sprague-Dawley Rats (2017)
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Stability studies of potent opioid analgesic, morphine‐6‐O‐sulfate in various buffers and biological matrices by HPLC‐DAD analysis (2017)
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X‐irradiation and Simulated Microgravity affects Rat Weight, Food Intake, Insulin and Paw Pressure Pain Threshold (2016)
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Antinociceptive effects of the 6- O -sulfate ester of morphine in normal and diabetic rats: Comparative role of mu- and delta-opioid receptors (2016)
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Degenerative Tissue Responses to Space-like Radiation Doses in a Rodent Model of Simulated Microgravity. (2016)
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Crystal structures of (Z)-5-[2-(benzo[b]thiophen-2-yl)-1-(3,5-dimethoxyphenyl)ethenyl]-1H-tetrazole and (Z)-5-[2-(benzo[b]thiophen-3-yl)-1-(3,4,5-trimethoxyphenyl)ethenyl]-1H-tetrazole (2016)
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A novel and efficient tributyltin azide-mediated synthesis of 1H-tetrazolylstilbenes from cyanostilbenes (2016)
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(434) Analgesic profile of morphine 6-O-sulfate sodium: a mixed mu/delta agonist in the treatment of diabetic neuropathic pain (2015)
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Synthesis and evaluation of a series of benzothiophene acrylonitrile analogs as anticancer agents (2013)
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Seeking Predictable Subject Characteristics That Influence Clinical Trial Discontinuation (2012)
Collaboration Network
Top Collaborators
Peter A. Crooks
University of Arkansas for Medical Sciences
11 shared publications
In database
- Synthesis and evaluation of a series of benzothiophene acrylonitrile analogs as anticancer agents
- Antinociceptive effects of the 6- O -sulfate ester of morphine in normal and diabetic rats: Comparative role of mu- and delta-opioid receptors
- Evaluation of Analgesia, Tolerance, and the Mechanism of Action of Morphine-6-O-Sulfate Across Multiple Pain Modalities in Sprague-Dawley Rats
- A novel and efficient tributyltin azide-mediated synthesis of 1H-tetrazolylstilbenes from cyanostilbenes
- Preclinical assessment of utility of M6S for multimodal acute and chronic pain treatment in diabetic neuropathy
Showing 5 of 11 shared publications
Maxim Dobretsov
University of Arkansas for Medical Sciences (US)
9 shared publications
- Antinociceptive effects of the 6- O -sulfate ester of morphine in normal and diabetic rats: Comparative role of mu- and delta-opioid receptors
- Evaluation of Analgesia, Tolerance, and the Mechanism of Action of Morphine-6-O-Sulfate Across Multiple Pain Modalities in Sprague-Dawley Rats
- Degenerative Tissue Responses to Space-like Radiation Doses in a Rodent Model of Simulated Microgravity.
- Preclinical assessment of utility of M6S for multimodal acute and chronic pain treatment in diabetic neuropathy
- Evaluation of morphine‐like effects of the mixed mu/delta agonist morphine‐6‐O‐sulfate in rats: Drug discrimination and physical dependence
Showing 5 of 9 shared publications
Narsimha Reddy Penthala
University of Arkansas for Medical Sciences
6 shared publications
In database
- Synthesis and evaluation of a series of benzothiophene acrylonitrile analogs as anticancer agents
- A novel and efficient tributyltin azide-mediated synthesis of 1H-tetrazolylstilbenes from cyanostilbenes
- Evaluation of morphine‐like effects of the mixed mu/delta agonist morphine‐6‐O‐sulfate in rats: Drug discrimination and physical dependence
- (434) Analgesic profile of morphine 6-O-sulfate sodium: a mixed mu/delta agonist in the treatment of diabetic neuropathic pain
- Crystal structures of (Z)-5-[2-(benzo[b]thiophen-2-yl)-1-(3,5-dimethoxyphenyl)ethenyl]-1H-tetrazole and (Z)-5-[2-(benzo[b]thiophen-3-yl)-1-(3,4,5-trimethoxyphenyl)ethenyl]-1H-tetrazole
Showing 5 of 6 shared publications
Paul L. Prather
University of Arkansas for Medical Sciences
5 shared publications
In database
- Antinociceptive effects of the 6- O -sulfate ester of morphine in normal and diabetic rats: Comparative role of mu- and delta-opioid receptors
- Evaluation of Analgesia, Tolerance, and the Mechanism of Action of Morphine-6-O-Sulfate Across Multiple Pain Modalities in Sprague-Dawley Rats
- Preclinical assessment of utility of M6S for multimodal acute and chronic pain treatment in diabetic neuropathy
- Pinprick hypo- and hyperalgesia in diabetic rats: Can diet content affect experimental outcome?
- (434) Analgesic profile of morphine 6-O-sulfate sodium: a mixed mu/delta agonist in the treatment of diabetic neuropathic pain
Navdeep Dogra
University of Arkansas for Medical Sciences (US)
4 shared publications
- Evaluation of Analgesia, Tolerance, and the Mechanism of Action of Morphine-6-O-Sulfate Across Multiple Pain Modalities in Sprague-Dawley Rats
- Preclinical assessment of utility of M6S for multimodal acute and chronic pain treatment in diabetic neuropathy
- Pinprick hypo- and hyperalgesia in diabetic rats: Can diet content affect experimental outcome?
- (434) Analgesic profile of morphine 6-O-sulfate sodium: a mixed mu/delta agonist in the treatment of diabetic neuropathic pain
Zaineb A.F. Albayati
University of Arkansas for Medical Sciences
3 shared publications
In database
- Stability studies of potent opioid analgesic, morphine‐6‐O‐sulfate in various buffers and biological matrices by HPLC‐DAD analysis
- (434) Analgesic profile of morphine 6-O-sulfate sodium: a mixed mu/delta agonist in the treatment of diabetic neuropathic pain
- A pharmacokinetic study of morphine‐6‐O ‐sulfate in rat plasma and brain
Anqi W. Walbaum
University of Arkansas for Medical Sciences
3 shared publications
In database
- Evaluation of Analgesia, Tolerance, and the Mechanism of Action of Morphine-6-O-Sulfate Across Multiple Pain Modalities in Sprague-Dawley Rats
- Preclinical assessment of utility of M6S for multimodal acute and chronic pain treatment in diabetic neuropathy
- Pinprick hypo- and hyperalgesia in diabetic rats: Can diet content affect experimental outcome?
Benjamin M. Ford
University of Arkansas for Medical Sciences (US)
2 shared publications
- Antinociceptive effects of the 6- O -sulfate ester of morphine in normal and diabetic rats: Comparative role of mu- and delta-opioid receptors
- (434) Analgesic profile of morphine 6-O-sulfate sodium: a mixed mu/delta agonist in the treatment of diabetic neuropathic pain
Parimal Chowdhury
University of Arkansas for Medical Sciences
2 shared publications
In database
- Degenerative Tissue Responses to Space-like Radiation Doses in a Rodent Model of Simulated Microgravity.
- X‐irradiation and Simulated Microgravity affects Rat Weight, Food Intake, Insulin and Paw Pressure Pain Threshold
Nisreen Akel
University of Arkansas for Medical Sciences
2 shared publications
In database
- Degenerative Tissue Responses to Space-like Radiation Doses in a Rodent Model of Simulated Microgravity.
- X‐irradiation and Simulated Microgravity affects Rat Weight, Food Intake, Insulin and Paw Pressure Pain Threshold
Robert J. Griffin
University of Arkansas for Medical Sciences
2 shared publications
In database
- Degenerative Tissue Responses to Space-like Radiation Doses in a Rodent Model of Simulated Microgravity.
- X‐irradiation and Simulated Microgravity affects Rat Weight, Food Intake, Insulin and Paw Pressure Pain Threshold
Anqi Wan
University of Arkansas for Medical Sciences
2 shared publications
In database
- Antinociceptive effects of the 6- O -sulfate ester of morphine in normal and diabetic rats: Comparative role of mu- and delta-opioid receptors
- Evaluation of morphine‐like effects of the mixed mu/delta agonist morphine‐6‐O‐sulfate in rats: Drug discrimination and physical dependence
Narasimha R. Penthala
University of Arkansas for Medical Sciences (US)
2 shared publications
- Antinociceptive effects of the 6- O -sulfate ester of morphine in normal and diabetic rats: Comparative role of mu- and delta-opioid receptors
- Stability studies of potent opioid analgesic, morphine‐6‐O‐sulfate in various buffers and biological matrices by HPLC‐DAD analysis
Howard P. Hendrickson
University of Arkansas for Medical Sciences (US)
2 shared publications
- Stability studies of potent opioid analgesic, morphine‐6‐O‐sulfate in various buffers and biological matrices by HPLC‐DAD analysis
- A pharmacokinetic study of morphine‐6‐O ‐sulfate in rat plasma and brain
I. G. Martin
Eastern Michigan University (US)
1 shared publication
- Seeking Predictable Subject Characteristics That Influence Clinical Trial Discontinuation
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