Jeffrey C. Wolchok Data-verified

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

Federal Grant PI

Professor/ DepartmentChairperson

University of Arkansas

Last publication 2025 Last refreshed 2026-05-22

faculty

17 h-index 49 pubs 779 cited

Research Areas

Links

ORCID Lab Website Research Group

OverviewAI-generated summary

Jeffrey C. Wolchok's research focuses on the biological mechanisms underlying tissue repair and regeneration, particularly in the context of skeletal muscle and traumatic brain injury. His work investigates strategies to enhance functional recovery following significant tissue damage. A key area of his investigation involves the use of cell-derived extracellular matrix (ECM) scaffolds, exploring how these biomaterials can promote tissue regeneration. He has also examined the role of specific biological agents, such as Interleukin-10 (IL-10), in modulating the immune response to facilitate muscle repair.

Wolchok's research extends to understanding the neurological consequences of injury. He has studied blood-brain barrier integrity and astrocyte reactivity following repeated traumatic brain injury, analyzing the associated molecular and cellular changes. His group employs advanced techniques, including transcriptome profiling, to identify key molecular pathways involved in injury and repair. Furthermore, Wolchok has received federal funding to support research infrastructure, including grants from the National Institutes of Health (NIH) and the National Science Foundation (NSF) for single-cell RNA sequencing instrumentation and biofiber engineering.

His scholarly contributions are reflected in a h-index of 16 and over 770 citations across 49 publications. Wolchok actively collaborates with researchers at the University of Arkansas at Fayetteville, including Tai Huynh, John Taehwan Kim, Tyrone A. Washington, and Jacob Schluns, with whom he has co-authored multiple publications. He also leads a research group and maintains an active laboratory website, indicating ongoing research activities.

Metrics

h-index: 17
Publications: 49
Citations: 779

Selected Publications

Aerobic Exercise Training Does Not Attenuate Fibrosis In Autologous Repaired Vml-injured Skeletal Muscle (2025)

DOI OpenAlex
BOARD # 307: University of Arkansas Biomedical Engineering REU Site: Training in Emerging Biomedical Optics and Imaging Approaches (2025)

DOI OpenAlex
Board 107: Work in Progress: Development of an Innovation Corps-Modeled Bioengineering Course to Promote Entrepreneurial Engagement among Undergraduate Students. (2024)

DOI OpenAlex
<i>In vivo</i> measurement of NADH fluorescence lifetime in skeletal muscle via fiber-coupled time-correlated single photon counting (2023)

3 citations DOI OpenAlex
Cell-Derived Extracellular Matrix Fiber Scaffolds Improve Recovery from Volumetric Muscle Loss (2023)

9 citations DOI OpenAlex
Transcriptome profiling of a synergistic volumetric muscle loss repair strategy (2023)

6 citations DOI OpenAlex
Prescribing reduced physical activity following volumetric muscle loss not really a good idea (2023)

1 citation DOI OpenAlex
Local IL-10 delivery modulates the immune response and enhances repair of volumetric muscle loss muscle injury (2023)

32 citations DOI OpenAlex
Transcriptome profiling of a synergistic volumetric muscle loss repair strategy (2023)

1 citation DOI OpenAlex
Delivery of a tissue derived extracellular matrix gel modulates early fibro-adipogenic cell behavior and improves recovery following both acute and chronic atrophy muscle injury (2022)

DOI OpenAlex
Local IL-10 delivery modulates the immune response and enhances repair of volumetric muscle loss muscle injury (2022)

1 citation DOI OpenAlex
Functional Analysis of the Cortical Transcriptome and Proteome Reveal Neurogenesis, Inflammation, and Cell Death after Repeated Traumatic Brain Injury <i>In vivo</i> (2022)

4 citations DOI OpenAlex
Nandrolone supplementation does not improve functional recovery in an aged animal model of volumetric muscle loss injury (2022)

7 citations DOI OpenAlex
Impact and Delivery of an Engineering Service Learning Course in a Remote Environment (2021)

DOI OpenAlex
Blood–Brain Barrier Breakdown and Astrocyte Reactivity Evident in the Absence of Behavioral Changes after Repeated Traumatic Brain Injury (2021)

21 citations DOI OpenAlex