Jessica R. Goree

Professor

UAMS

Also affiliated: University of Arkansas Medical Center (2014–2015); Central Arkansas Veterans Healthcare System (2014–2017)

5 h-index 9 pubs 122 cited

Research Areas

Biomedical Subjects

OverviewAI-generated summary

Jessica R. Goree's research has investigated mechanisms of liver injury and fibrosis, particularly in response to toxic insults like carbon tetrachloride. Her work has explored the role of myofibroblasts and specific gene expression in the development of hepatic stellate cells, which are key players in fibrotic scarring of the liver. Goree has also examined changes in the pulmonary circulation associated with cirrhosis in animal models. In parallel, her research has touched upon purinergic signaling pathways in human liver cells and the genetic basis for diseases, including mutations in the NT5E gene and their impact on protein trafficking. Her publications include studies on cell line establishment, pathological changes in animal models, and the expression of mediators involved in cellular signaling and survival during disease states.

Metrics

h-index: 5
Publications: 9
Citations: 122

Positions

Professor publications 2014–2019

University of Arkansas for Medical Sciences Institution web page

Selected Publications

Reduction in SNAP-23 Alters Microfilament Organization in Myofibrobastic Hepatic Stellate Cells (2019)

Gene Expression 3 citations DOI OpenAlex
The Cholangiocyte Adenosine‐IL-6 Axis Regulates Survival During Biliary Cirrhosis (2017)

Gene Expression 9 citations DOI OpenAlex
An Elf2-like transcription factor acts as repressor of the mouse ecto-5′-nucleotidase gene expression in hepatic myofibroblasts (2017)

Purinergic Signalling 5 citations DOI OpenAlex
Establishment and Characterization of Rat Portal Myofibroblast Cell Lines (2015)

PLoS ONE 33 citations DOI OpenAlex
Expression of mediators of purinergic signaling in human liver cell lines (2014)

Purinergic Signalling 13 citations DOI OpenAlex
MCP-1 downregulates MMP-9 export via vesicular redistribution to lysosomes in rat portal fibroblasts (2014)

Physiological Reports 3 citations DOI OpenAlex
NT5E Mutations That Cause Human Disease Are Associated with Intracellular Mistrafficking of NT5E Protein (2014)

PLoS ONE 20 citations DOI OpenAlex
Pathological Changes in Pulmonary Circulation in Carbon Tetrachloride (ccl4)-Induced Cirrhotic Mice (2014)

PLoS ONE 32 citations DOI OpenAlex