John B. Sutherland
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Also affiliated: Michigan Technological University (1986–1988); Texas Tech University (1984); United States Food and Drug Administration (1990–2023); United States Department of Agriculture (1980); University of Wisconsin–Madison (1978); Uniformed Services University of the Health Sciences (1993); University of Idaho (1979–1988); Colorado School of Mines (1999); Georgia State University (1993); United States Public Health Service (2000); Washington State University (1980)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
John B. Sutherland is a researcher with a h-index of 35 and 122 total publications, accumulating over 4,500 citations. His research interests encompass the biotransformation of antibacterial agents, particularly fluoroquinolones, and the application of analytical techniques such as high-pressure liquid chromatography, magnetic resonance spectroscopy, and mass spectrometry. He has investigated the metabolism and effects of these compounds in various biological systems, including humans, animals, and bacteria. Sutherland's work also includes developing and applying bioinformatics tools for genomic analysis, as demonstrated by his recent publication on CPGminer, an interactive dashboard for exploring prokaryotic genome features and taxonomy. He has collaborated with researchers from institutions including the National Center for Toxicological Research, the University of Arkansas at Little Rock, and the University of Arkansas for Medical Sciences.
Metrics
- h-index: 35
- Publications: 107
- Citations: 4,446
Selected Publications
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CPGminer: An Interactive Dashboard to Explore the Genomic Features and Taxonomy of Complete Prokaryotic Genomes (2023)
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CYPminer: an automated cytochrome P450 identification, classification, and data analysis tool for genome data sets across kingdoms (2020)
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β-Lactam resistance development affects binding of penicillin-binding proteins (PBPs) of Clostridium perfringens to the fluorescent penicillin, BOCILLIN FL (2020)
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Rapid Analytical Methods to Identify Antibiotic‐Resistant Bacteria (2019)
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Effects of nano-hydroxyapatite on the formation of biofilms by Streptococcus mutans in two different media (2019)
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Applications of Biofilm and Quorum Sensing Inhibitors in Food Protection and Safety (2017)
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Plant‐Associated Biofilms Formed by Enteric Bacterial Pathogens and Their Significance (2017)
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Bacterial Populations Associated with Smokeless Tobacco Products (2016)
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Biotransformations of organic compounds mediated by cultures of Aspergillus niger (2015)
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Biotransformation of Steroids and Flavonoids by Cultures of Aspergillus niger (2015)
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Dynamic Response of Mycobacterium vanbaalenii PYR-1 to BP Deepwater Horizon Crude Oil (2015)
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Comparative functional pan-genome analyses to build connections between genomic dynamics and phenotypic evolution in polycyclic aromatic hydrocarbon metabolism in the genus Mycobacterium (2015)
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Level 2 validation of a flow cytometric method for detection of Escherichia coli O157:H7 in raw spinach (2015)
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Pleiotropic and Epistatic Behavior of a Ring-Hydroxylating Oxygenase System in the Polycyclic Aromatic Hydrocarbon Metabolic Network from Mycobacterium vanbaalenii PYR-1 (2014)
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The use of Aspergillus niger cultures for biotransformation of terpenoids (2014)
Collaboration Network
Top Collaborators
- The fungus Pestalotiopsis guepini as a model for biotransformation of ciprofloxacin and norfloxacin
- Regioselective transformation of ciprofloxacin toN-acetylciprofloxacin by the fungusMucor ramannianus
- Biotransformation of flumequine by the fungus Cunninghamella elegans
- Metabolism of the veterinary fluoroquinolone sarafloxacin by the fungus Mucor ramannianus
- Determination of fumonisins B1, B2, B3 and B4 by high-performance liquid chromatography with evaporative light-scattering detection
Showing 5 of 28 shared publications
- Metabolism of phenanthrene by Phanerochaete chrysosporium
- The fungus Pestalotiopsis guepini as a model for biotransformation of ciprofloxacin and norfloxacin
- Regioselective transformation of ciprofloxacin toN-acetylciprofloxacin by the fungusMucor ramannianus
- Stereoselective formation of a K-region dihydrodiol from phenanthrene by Streptomyces flavovirens
- Biotransformation of flumequine by the fungus Cunninghamella elegans
Showing 5 of 27 shared publications
- Identification of Bacterial Proteins Observed in MALDI TOF Mass Spectra from Whole Cells
- Interaction of dietary resveratrol with animal-associated bacteria
- The fungus Pestalotiopsis guepini as a model for biotransformation of ciprofloxacin and norfloxacin
- Modification of Norfloxacin by a Microbacterium sp. Strain Isolated from a Wastewater Treatment Plant
- Acetylation of fluoroquinolone antimicrobial agents by anEscherichia colistrain isolated from a municipal wastewater treatment plant
Showing 5 of 21 shared publications
- Degradation of Polycyclic Aromatic Hydrocarbons by Fungi
- Metabolism of phenanthrene by Phanerochaete chrysosporium
- Stereoselective formation of a K-region dihydrodiol from phenanthrene by Streptomyces flavovirens
- Use of a bioassay to evaluate the toxicity of beauvericin to bacteria
- Comparative functional pan-genome analyses to build connections between genomic dynamics and phenotypic evolution in polycyclic aromatic hydrocarbon metabolism in the genus Mycobacterium
Showing 5 of 19 shared publications
- Rapid Identification of Intact Whole Bacteria Based on Spectral Patterns using Matrix-assisted Laser Desorption/Ionization with Time-of-flight Mass Spectrometry
- Identification of Bacterial Proteins Observed in MALDI TOF Mass Spectra from Whole Cells
- Matrix-assisted laser desorption/ionization time-of-flight mass spectrometric detection of bacterial biomarker proteins isolated from contaminated water, lettuce and cotton cloth
- Reduction of Nitrazepam by Clostridium leptum, a Nitroreductase‐Producing Bacterium Isolated from the Human Intestinal Tract.
- Isolation of bacterial strains from bovine fecal microflora capable of degradation of ceftiofur
Showing 5 of 17 shared publications
- The fungus Pestalotiopsis guepini as a model for biotransformation of ciprofloxacin and norfloxacin
- Regioselective transformation of ciprofloxacin toN-acetylciprofloxacin by the fungusMucor ramannianus
- Biotransformation of Steroids and Flavonoids by Cultures of Aspergillus niger
- The use of Aspergillus niger cultures for biotransformation of terpenoids
- Microbial transformation of antimalarial terpenoids
Showing 5 of 15 shared publications
- Rapid Identification of Intact Whole Bacteria Based on Spectral Patterns using Matrix-assisted Laser Desorption/Ionization with Time-of-flight Mass Spectrometry
- Sample preparation for the analysis of flavors and off-flavors in foods
- Sample preparation and high-resolution separation of mycotoxins possessing carboxyl groups
- Reduction of food matrix interference by a combination of sample preparation and multi-dimensional gating techniques to facilitate rapid, high sensitivity analysis for Escherichia coli serotype O157 by flow cytometry
- Determination of fumonisins B1, B2, B3 and B4 by high-performance liquid chromatography with evaporative light-scattering detection
Showing 5 of 11 shared publications
- Rapid Identification of Intact Whole Bacteria Based on Spectral Patterns using Matrix-assisted Laser Desorption/Ionization with Time-of-flight Mass Spectrometry
- Identification of Bacterial Proteins Observed in MALDI TOF Mass Spectra from Whole Cells
- Regioselective transformation of ciprofloxacin toN-acetylciprofloxacin by the fungusMucor ramannianus
- Metabolism of the veterinary fluoroquinolone sarafloxacin by the fungus Mucor ramannianus
- Matrix-assisted laser desorption/ionization time-of-flight mass spectrometric detection of bacterial biomarker proteins isolated from contaminated water, lettuce and cotton cloth
Showing 5 of 9 shared publications
- The fungus Pestalotiopsis guepini as a model for biotransformation of ciprofloxacin and norfloxacin
- Metabolism of the veterinary fluoroquinolone sarafloxacin by the fungus Mucor ramannianus
- Formation of conjugates from ciprofloxacin and norfloxacin in cultures ofTrichoderma viride
- Biotransformation of N -acetylphenothiazine by fungi
- Fungal biotransformation of benzo[f]quinoline, benzo[h]quinoline, and phenanthridine
Showing 5 of 9 shared publications
- Bacterial Populations Associated with Smokeless Tobacco Products
- Biotransformation of flumequine by the fungus Cunninghamella elegans
- Identification of metabolites produced from acridine by Cunninghamella elegans
- Biotransformation of acridine byMycobacterium vanbaalenii
- Conversion of Ferulic Acid to 4-Vinylguaiacol by Yeasts Isolated from Frozen Concentrated Orange Juice
Showing 5 of 8 shared publications
- Reduction of food matrix interference by a combination of sample preparation and multi-dimensional gating techniques to facilitate rapid, high sensitivity analysis for Escherichia coli serotype O157 by flow cytometry
- Rapid phenotypic characterization of Salmonella enterica strains by pyrolysis metastable atom bombardment mass spectrometry with multivariate statistical and artificial neural network pattern recognition
- Photobleaching with phloxine B sensitizer to reduce food matrix interference for detection of Escherichia coli serotype O157:H7 in fresh spinach by flow cytometry
- Level 2 validation of a flow cytometric method for detection of Escherichia coli O157:H7 in raw spinach
- Pyrolysis mass spectrometry for distinguishing potential hoax materials from bioterror agents
- Isolation of bacterial strains from bovine fecal microflora capable of degradation of ceftiofur
- Effects of nano-hydroxyapatite on the formation of biofilms by Streptococcus mutans in two different media
- Effect of Fluoroquinolone Resistance Selection on the Fitness of Three Strains of Clostridium perfringens
- β-Lactam resistance development affects binding of penicillin-binding proteins (PBPs) of Clostridium perfringens to the fluorescent penicillin, BOCILLIN FL
- Relationship of Dietary Soy Protein to Daidzein Metabolism by Cultures of Intestinal Microfloras from Monkeys
- Comparative functional pan-genome analyses to build connections between genomic dynamics and phenotypic evolution in polycyclic aromatic hydrocarbon metabolism in the genus Mycobacterium
- Dynamic Response of Mycobacterium vanbaalenii PYR-1 to BP Deepwater Horizon Crude Oil
- Pleiotropic and Epistatic Behavior of a Ring-Hydroxylating Oxygenase System in the Polycyclic Aromatic Hydrocarbon Metabolic Network from Mycobacterium vanbaalenii PYR-1
- Identification of the Enzyme Responsible forN-Acetylation of Norfloxacin by Microbacterium sp. Strain 4N2-2
- CYPminer: an automated cytochrome P450 identification, classification, and data analysis tool for genome data sets across kingdoms
- Rapid Identification of Intact Whole Bacteria Based on Spectral Patterns using Matrix-assisted Laser Desorption/Ionization with Time-of-flight Mass Spectrometry
- Identification of Bacterial Proteins Observed in MALDI TOF Mass Spectra from Whole Cells
- Matrix-assisted laser desorption/ionization time-of-flight mass spectrometric detection of bacterial biomarker proteins isolated from contaminated water, lettuce and cotton cloth
- Matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometric detection of bacterial biomarker proteins isolated from contaminated water, lettuce and cotton cloth
- Rapid Identification of Intact Whole Bacteria Based on Spectral Patterns using Matrix-assisted Laser Desorption/Ionization with Time-of-flight Mass Spectrometry
- Identification of Bacterial Proteins Observed in MALDI TOF Mass Spectra from Whole Cells
- Matrix-assisted laser desorption/ionization time-of-flight mass spectrometric detection of bacterial biomarker proteins isolated from contaminated water, lettuce and cotton cloth
- Matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometric detection of bacterial biomarker proteins isolated from contaminated water, lettuce and cotton cloth
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