Larry D. Hartzell
Assistant Professor
faculty
Otolaryngology, College of Medicine
Research Areas
Biography and Research Information
OverviewAI-generated summary
Dr. Larry Hartzell's research focuses on pediatric otolaryngology, with a particular emphasis on the surgical and functional outcomes of interventions for congenital anomalies and common childhood conditions. He directs the cleft team at Arkansas Children's Hospital (ACH), investigating areas such as the effectiveness of different surgical techniques for velopharyngeal insufficiency and the application of algorithms like GILLS to mandibular distraction procedures.
His work also explores the broader impacts of medical education and the development of standardized curricula, as evidenced by his research on a suture curriculum for medical students. Dr. Hartzell's publications include studies on the morbidity associated with specific genetic syndromes, the clinical significance of screening electrocardiograms for infantile hemangiomas, and the geographic distribution of orofacial cleft anomalies. He collaborates with researchers at the University of Arkansas for Medical Sciences, including James Reed Gardner, Olivia Speed, Gresham T. Richter, and Yuri A. Zárate.
With an h-index of 11 and 43 total publications, Dr. Hartzell's scholarship contributes to the understanding and treatment of conditions affecting children. He is board-certified by the American Board of Otolaryngology – Head and Neck Surgery and is recognized as a Certified Complex Pediatric Otolaryngologist.
Research Overview
Dr. Larry Hartzell attended Brigham Young University where he received his undergraduate degree in Zoology with a human biology emphasis. He spent 2 years as a missionary for his Church in Colombia where he became fluent in Spanish. Dr. Hartzell earned his medical degree at The University of Arizona College of Medicine. He completed a residency in Otolaryngology (ENT) at the University of Arkansas for Medical Sciences. He then completed fellowship training in Pediatric Otolaryngology at Arkansas Children's Hospital (ACH). He has been the director of the cleft team at ACH since 2012. Dr. Hartzell is an active participant in multiple local as well as national committees and is academically active with many peer reviewed articles in addition to book chapters and other publications. He is board certified by the American Board of Otolaryngology – Head and Neck Surgery and is a Certified Complex Pediatric Otolaryngologist. He is a member of numerous medical organizations, including the American Academy of Pediatrics, American Cleft Palate-Craniofacial Association, American Academy of Facial Plastic and Reconstructive Surgery and the American Academy of Otolaryngology, Head and Neck Surgery. His major research interests include cleft lip and palate medical and surgical management as well as velopharyngeal insufficiency. Dr. Hartzell has a strong interest in medical humanitarian mission efforts and has participated in humanitarian efforts in China, Guatemala, Egypt and Ecuador. He is a Professor of Otolaryngology and also the Program Director of the Pediatric Otolaryngology Fellowship at Arkansas Children's Hospital. He also provides surgical care at Arkansas Children's Northwest.
Metrics
- h-index: 11
- Publications: 43
- Citations: 412
Selected Publications
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Clicking larynx syndrome in an adolescent patient following trauma: A case report and review of current literature (2026)
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Surgical Repair of Unilateral Cleft Alveolus Using Viable Bone Allograft in Pediatrics: A Case Report (2025)
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Evaluating Geographic Distribution and Potential Environmental Risk Factors of Orofacial Cleft Anomalies Utilizing a Statewide Birth Defects Registry (2025)
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Myringoplasty Using Human Birth Tissue Allografts to Repair Large Tympanic Membrane Perforations (2024)
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Is There Utility in Preoperative Testing of Hemoglobin Before Primary Cheiloplasty? (2024)
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Outcomes After Pharyngeal Flap Surgery in Children: A Comparison of Lined Versus Unlined Flaps (2023)
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Quantitative Phenotype Morbidity Description of SATB2-Associated Syndrome (2023)
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P369: SATB2-associated syndrome severity score: Genotype/phenotype correlations and the SATB2 portal (2023)
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The First Hybrid International Educational Comprehensive Cleft Care Workshop (2022)
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Retrospective Examination of the GILLS Algorithm Applied to Mandibular Distraction (2021)
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Clinical Significance of Screening Electrocardiograms for the Administration of Propranolol for Problematic Infantile Hemangiomas (2021)
Research Interests
Dr. Hartzell’s first exposure to research was during his undergraduate study years at Brigham Young University. He was able to participate in multiple projects in a chemistry laboratory during that time, mostly related to ancient Egyptian Mummies, which exposed him to much of the bench-top research techniques and protocols. His research experience continued in medical school at the University Of Arizona College Of Medicine where he took the opportunity to apply for an NIH student grant that allowed him to once again work in a chemistry lab. This time he studied the brown recluse spider and its relatives isolating the active enzyme in their venom. Upon entering residency in Otolaryngology Head and Neck Surgery and UAMS, Dr. Hartzell sought out opportunities to further engage in research and was able to become involved with multiple clinical research projects that led to publication and podium presentations as well as posters. This played a part in motivating Dr. Hartzell to pursue his academic interests in fellowship and future employment in the academic institution of UAMS. Dr. Hartzell was productive as a fellow participating in some international meetings and this expanded as he became faculty at UAMS. As a busy clinician, much of Dr. Hartzell’s time has been dedicated to direct patient care as well as his administrative duties as cleft team director and fellowship director among other things. As a result, the amount of time that he has been able to dedicate solely to research has been unfortunately limited. However, through working with students and trainees of multiple levels, Dr. Hartzell has been able to continue to be academically active in the research arena. He continues to present at national and international meetings on the clinical work he is engaged in and the students, residents and fellows he has mentored in this process. His biggest research accomplishments have been the development and maintenance of a new cleft and craniofacial database to allow for quality improvement projects as well as data for a myriad of possible scientific protocols and projects. This is actively being populated and studies generated from this database.
Collaboration Network
Top Collaborators
- Retrospective Examination of the GILLS Algorithm Applied to Mandibular Distraction
- Quantitative Phenotype Morbidity Description of SATB2-Associated Syndrome
- Evaluating Geographic Distribution and Potential Environmental Risk Factors of Orofacial Cleft Anomalies Utilizing a Statewide Birth Defects Registry
- Clinical Significance of Screening Electrocardiograms for the Administration of Propranolol for Problematic Infantile Hemangiomas
- Impact of Surgery for Velopharyngeal Insufficiency on Eustachian Tube Function in Children: Pharyngeal Flap Versus Sphincter Pharyngoplasty
Showing 5 of 7 shared publications
- Quantitative Phenotype Morbidity Description of SATB2-Associated Syndrome
- Impact of Surgery for Velopharyngeal Insufficiency on Eustachian Tube Function in Children: Pharyngeal Flap Versus Sphincter Pharyngoplasty
- Outcomes After Pharyngeal Flap Surgery in Children: A Comparison of Lined Versus Unlined Flaps
- P369: SATB2-associated syndrome severity score: Genotype/phenotype correlations and the SATB2 portal
- Clinical Significance of Screening Electrocardiograms for the Administration of Propranolol for Problematic Infantile Hemangiomas
- Impact of Surgery for Velopharyngeal Insufficiency on Eustachian Tube Function in Children: Pharyngeal Flap Versus Sphincter Pharyngoplasty
- Outcomes After Pharyngeal Flap Surgery in Children: A Comparison of Lined Versus Unlined Flaps
- Improved Confidence and Clinical Application: The Effects of a Longitudinal Suture Curriculum for Medical Students
- Impact of Surgery for Velopharyngeal Insufficiency on Eustachian Tube Function in Children: Pharyngeal Flap Versus Sphincter Pharyngoplasty
- Outcomes After Pharyngeal Flap Surgery in Children: A Comparison of Lined Versus Unlined Flaps
- Clinical Significance of Screening Electrocardiograms for the Administration of Propranolol for Problematic Infantile Hemangiomas
- Myringoplasty Using Human Birth Tissue Allografts to Repair Large Tympanic Membrane Perforations
- Impact of Surgery for Velopharyngeal Insufficiency on Eustachian Tube Function in Children: Pharyngeal Flap Versus Sphincter Pharyngoplasty
- Outcomes After Pharyngeal Flap Surgery in Children: A Comparison of Lined Versus Unlined Flaps
- Quantitative Phenotype Morbidity Description of SATB2-Associated Syndrome
- P369: SATB2-associated syndrome severity score: Genotype/phenotype correlations and the SATB2 portal
- Quantitative Phenotype Morbidity Description of SATB2-Associated Syndrome
- P369: SATB2-associated syndrome severity score: Genotype/phenotype correlations and the SATB2 portal
- Quantitative Phenotype Morbidity Description of SATB2-Associated Syndrome
- P369: SATB2-associated syndrome severity score: Genotype/phenotype correlations and the SATB2 portal
- Quantitative Phenotype Morbidity Description of SATB2-Associated Syndrome
- P369: SATB2-associated syndrome severity score: Genotype/phenotype correlations and the SATB2 portal
- Quantitative Phenotype Morbidity Description of SATB2-Associated Syndrome
- P369: SATB2-associated syndrome severity score: Genotype/phenotype correlations and the SATB2 portal
- Quantitative Phenotype Morbidity Description of SATB2-Associated Syndrome
- P369: SATB2-associated syndrome severity score: Genotype/phenotype correlations and the SATB2 portal
- Quantitative Phenotype Morbidity Description of SATB2-Associated Syndrome
- P369: SATB2-associated syndrome severity score: Genotype/phenotype correlations and the SATB2 portal
- Quantitative Phenotype Morbidity Description of SATB2-Associated Syndrome
- P369: SATB2-associated syndrome severity score: Genotype/phenotype correlations and the SATB2 portal
- Quantitative Phenotype Morbidity Description of SATB2-Associated Syndrome
- P369: SATB2-associated syndrome severity score: Genotype/phenotype correlations and the SATB2 portal
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