Matthew S. Kelly
Section Chief, Infectious Diseases
faculty
COM | Peds Infectious Diseases
Research Areas
Biography and Research Information
OverviewAI-generated summary
Matthew S. Kelly leads a research group focused on infectious diseases, with a particular emphasis on viral infections and the human microbiome in pediatric populations. His work has investigated host responses to SARS-CoV-2, including durable neutralizing antibody responses in children and adolescents following asymptomatic or mild infections. Kelly's research also explores the relationship between age-related changes in the nasopharyngeal microbiome and susceptibility to SARS-CoV-2. He has published on the role of non-diphtheriae Corynebacterium species in decreasing the risk of pneumococcal colonization during infancy and has evaluated the potential of Dolosigranulum pigrum as a nasal probiotic candidate.
Further research interests include the evaluation of novel vaccine candidates, such as recombinant live-attenuated respiratory syncytial virus (RSV) vaccines in children. Kelly has also examined risk factors for cytomegalovirus (CMV) viremia and associated adverse events in pediatric hematopoietic stem cell transplant recipients. His scholarship metrics include an h-index of 25, with 131 total publications and 1,986 total citations, marking him as a highly cited researcher.
Metrics
- h-index: 26
- Publications: 131
- Citations: 2,030
Selected Publications
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Health Utilities Associated with Pneumococcal Diseases in Children and Adults: A Targeted Literature Review and Meta-analysis (2026)
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Early life factors documented in electronic health records predict recurrent acute otitis media (2026)
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Indirect Effects in Health Economic Models of Vaccines: Should We Include Them, and How Do We Model Them? (2026)
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P-484. Global Economic Burden Of Pneumococcal Disease In Children — Lessons Learned From Economic Evaluations Of Pneumococcal Vaccines (2026)
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Indirect comparison of the immunogenicity of 15-valent and 20-valent pneumococcal conjugate vaccines in children using a 2+1 schedule (2025)
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Alterations of the upper respiratory microbiome among children living with HIV infection in Botswana (2022)
Collaboration Network
Top Collaborators
- Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents
- Age-Related Changes in the Nasopharyngeal Microbiome Are Associated With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Symptoms Among Children, Adolescents, and Young Adults
- Non-diphtheriae <i>Corynebacterium</i> species are associated with decreased risk of pneumococcal colonization during infancy
- Dolosigranulum pigrum: A promising nasal probiotic candidate
- Asthma and the Risk of SARS-CoV-2 Infection Among Children and Adolescents
Showing 5 of 19 shared publications
- Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents
- Age-Related Changes in the Nasopharyngeal Microbiome Are Associated With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Symptoms Among Children, Adolescents, and Young Adults
- Non-diphtheriae <i>Corynebacterium</i> species are associated with decreased risk of pneumococcal colonization during infancy
- Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents
- Age-related changes in the upper respiratory microbiome are associated with SARS-CoV-2 susceptibility and illness severity
Showing 5 of 9 shared publications
- Age-Related Changes in the Nasopharyngeal Microbiome Are Associated With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Symptoms Among Children, Adolescents, and Young Adults
- Risk Factors for CMV Viremia and Treatment-Associated Adverse Events Among Pediatric Hematopoietic Stem Cell Transplant Recipients
- The effects of antibiotic exposures on the gut resistome during hematopoietic cell transplantation in children
- Strain-resolved metagenomic analysis of the gut as a reservoir for bloodstream infection pathogens among premature infants in Singapore
- Age-related changes in the upper respiratory microbiome are associated with SARS-CoV-2 susceptibility and illness severity
Showing 5 of 8 shared publications
- Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents
- Age-Related Changes in the Nasopharyngeal Microbiome Are Associated With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Symptoms Among Children, Adolescents, and Young Adults
- Epstein-Barr Virus DNAemia and post-transplant lymphoproliferative disorder in pediatric solid organ transplant recipients
- Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents
- Age-related changes in the upper respiratory microbiome are associated with SARS-CoV-2 susceptibility and illness severity
Showing 5 of 8 shared publications
- Non-diphtheriae <i>Corynebacterium</i> species are associated with decreased risk of pneumococcal colonization during infancy
- Risk Factors for CMV Viremia and Treatment-Associated Adverse Events Among Pediatric Hematopoietic Stem Cell Transplant Recipients
- The effects of antibiotic exposures on the gut resistome during hematopoietic cell transplantation in children
- Evolution of pneumococcal serotype epidemiology in Botswana following introduction of 13-valent pneumococcal conjugate vaccine
- Epstein-Barr Virus DNAemia and post-transplant lymphoproliferative disorder in pediatric solid organ transplant recipients
Showing 5 of 8 shared publications
- Non-diphtheriae <i>Corynebacterium</i> species are associated with decreased risk of pneumococcal colonization during infancy
- Evolution of pneumococcal serotype epidemiology in Botswana following introduction of 13-valent pneumococcal conjugate vaccine
- Optimising the management of childhood acute diarrhoeal disease using a rapid test-and- treat strategy and/or <i>Lactobacillus reuteri</i> DSM 17938: a multicentre, randomised, controlled, factorial trial in Botswana
- Kinetics of pneumococcal antibodies among HIV-exposed, uninfected infants in Botswana
- Serotype epidemiology and antibiotic resistance of pneumococcal isolates colonizing infants in Botswana (2016–2019)
Showing 5 of 8 shared publications
- Dysregulated transcriptional responses to SARS-CoV-2 in the periphery
- Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents
- Age-Related Changes in the Nasopharyngeal Microbiome Are Associated With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Symptoms Among Children, Adolescents, and Young Adults
- Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents
- Age-related changes in the upper respiratory microbiome are associated with SARS-CoV-2 susceptibility and illness severity
Showing 5 of 7 shared publications
- Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents
- Age-Related Changes in the Nasopharyngeal Microbiome Are Associated With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Symptoms Among Children, Adolescents, and Young Adults
- Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents
- Age-related changes in the upper respiratory microbiome are associated with SARS-CoV-2 susceptibility and illness severity
- Age-associated differences in mucosal and systemic host responses to SARS-CoV-2 infection
Showing 5 of 7 shared publications
- Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents
- Age-Related Changes in the Nasopharyngeal Microbiome Are Associated With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Symptoms Among Children, Adolescents, and Young Adults
- Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents
- Age-related changes in the upper respiratory microbiome are associated with SARS-CoV-2 susceptibility and illness severity
- Age-associated differences in mucosal and systemic host responses to SARS-CoV-2 infection
Showing 5 of 7 shared publications
- Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents
- Age-Related Changes in the Nasopharyngeal Microbiome Are Associated With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Symptoms Among Children, Adolescents, and Young Adults
- Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents
- Age-related changes in the upper respiratory microbiome are associated with SARS-CoV-2 susceptibility and illness severity
- Age-associated differences in mucosal and systemic host responses to SARS-CoV-2 infection
Showing 5 of 7 shared publications
- Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents
- Age-Related Changes in the Nasopharyngeal Microbiome Are Associated With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Symptoms Among Children, Adolescents, and Young Adults
- Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents
- Age-related changes in the upper respiratory microbiome are associated with SARS-CoV-2 susceptibility and illness severity
- Age-associated differences in mucosal and systemic host responses to SARS-CoV-2 infection
Showing 5 of 7 shared publications
- Non-diphtheriae <i>Corynebacterium</i> species are associated with decreased risk of pneumococcal colonization during infancy
- Evolution of pneumococcal serotype epidemiology in Botswana following introduction of 13-valent pneumococcal conjugate vaccine
- Kinetics of pneumococcal antibodies among HIV-exposed, uninfected infants in Botswana
- Serotype epidemiology and antibiotic resistance of pneumococcal isolates colonizing infants in Botswana (2016–2019)
- Dolosigranulum savutiense sp. nov., isolated from human upper respiratory samples collected in Botswana
Showing 5 of 7 shared publications
- Evaluation of Recombinant Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccines RSV/ΔNS2/Δ1313/I1314L and RSV/276 in RSV-Seronegative Children
- Non-diphtheriae <i>Corynebacterium</i> species are associated with decreased risk of pneumococcal colonization during infancy
- Evolution of pneumococcal serotype epidemiology in Botswana following introduction of 13-valent pneumococcal conjugate vaccine
- Kinetics of pneumococcal antibodies among HIV-exposed, uninfected infants in Botswana
- Serotype epidemiology and antibiotic resistance of pneumococcal isolates colonizing infants in Botswana (2016–2019)
Showing 5 of 7 shared publications
- Non-diphtheriae <i>Corynebacterium</i> species are associated with decreased risk of pneumococcal colonization during infancy
- Evolution of pneumococcal serotype epidemiology in Botswana following introduction of 13-valent pneumococcal conjugate vaccine
- Cost-Effectiveness Analysis of Routine Childhood Immunization with 20-Valent versus 15-Valent Pneumococcal Conjugate Vaccines in Germany
- Health state utilities associated with invasive pneumococcal disease, pneumonia, and recurrent acute otitis media in young children
- Alterations of the upper respiratory microbiome among children living with HIV infection in Botswana
Showing 5 of 6 shared publications
- Non-diphtheriae <i>Corynebacterium</i> species are associated with decreased risk of pneumococcal colonization during infancy
- Evolution of pneumococcal serotype epidemiology in Botswana following introduction of 13-valent pneumococcal conjugate vaccine
- Kinetics of pneumococcal antibodies among HIV-exposed, uninfected infants in Botswana
- Dolosigranulum savutiense sp. nov., isolated from human upper respiratory samples collected in Botswana
- Alterations of the upper respiratory microbiome among children living with HIV infection in Botswana
Showing 5 of 6 shared publications
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