Michael R. Bishop

High Impact

Professor of Medicine

University of Arkansas for Medical Sciences

faculty

37 h-index 274 pubs 6,465 cited

Research Areas

CAR-T cell therapy research Acute Lymphoblastic Leukemia research Lymphoma Diagnosis and Treatment Multiple Myeloma Research and Treatments Cancer Immunotherapy and Biomarkers Immune Cell Function and Interaction Health and Medical Research Impacts Immune Response and Inflammation

Links

ORCID Lab Website UAMS TRI Profile

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OverviewAI-generated summary

Michael R. Bishop's research focuses on the treatment of hematological malignancies, particularly acute lymphoblastic leukemia and aggressive B-cell lymphomas, utilizing advanced immunotherapies such as chimeric antigen receptor (CAR) T-cell therapy. He has contributed to significant clinical trials investigating the efficacy and safety of CAR T-cell agents, including KTE-X19 and tisagenlecleucel, in relapsed or refractory adult B-cell acute lymphoblastic leukemia and aggressive B-cell lymphomas. His work also includes studies on the management of complications associated with CAR T-cell therapy, such as hemophagocytic lymphohistiocytosis.

Bishop has also explored treatments for multiple myeloma, investigating novel CAR T-cell therapies like CART-ddBCMA. His publications reflect a commitment to advancing the understanding and application of these complex therapeutic modalities in challenging patient populations. He has authored or co-authored over 270 publications and has an h-index of 37, with more than 6,400 citations.