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Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-15
Michael J. Mancino profile photo

Michael J. Mancino

CAST Program Director

Also affiliated: University of Louisville (1992–1996); University of Arkansas Medical Center (2010); Central Arkansas Veterans Healthcare System (2006–2010); Centers for Behavioral Health (2001); Azienda Usl Toscana Centro (2016–2017)

Faculty Researcher

PSY Psychiatry, College of Medicine

16 h-index 61 pubs 900 cited

  • Humans
  • Male
  • Female
  • Adult
  • Opioid-Related Disorders
  • Opiate Substitution Treatment
  • Middle Aged
  • Buprenorphine
  • Narcotic Antagonists
  • Methadone
  • Double-Blind Method
  • Cocaine-Related Disorders
  • Young Adult
  • Methamphetamine
  • Gabapentin

Biography and Research Information

OverviewAI-generated summary

Dr. Michael J. Mancino's research focuses on substance use disorders, with a particular emphasis on opioid and stimulant use. He investigates pharmacological and behavioral interventions to improve treatment outcomes for individuals with these conditions.

Dr. Mancino's work includes clinical trials examining the efficacy of medications such as buprenorphine and naltrexone for opioid use disorder. He has also studied the utility of gabapentin in managing stimulant withdrawal and supported the transition to injectable naltrexone. His research explores factors influencing treatment retention and advancement, including the impact of anxiety severity. Additionally, Dr. Mancino investigates trends in stimulant use and disparities in access to detoxification services.

His publications address the development and validation of analytical methods for quantifying medications in biological samples, crucial for pharmacokinetic and pharmacodynamic studies. Dr. Mancino's research network includes collaborators such as Alison Oliveto and Jeff D. Thostenson at the University of Arkansas for Medical Sciences. He is also the CAST Program Director at the UAMS Psychiatric Research Institute, overseeing research and treatment services for addiction.

Research Overview

Dr. Michael J. Mancino is a Professor in the UAMS Department of Psychiatry and the program director of the Center for Addiction Services and Treatment in the Psychiatric Research Institute.

Metrics

  • h-index: 16
  • Publications: 61
  • Citations: 900

Selected Publications

  • Geospatial ecological momentary assessment (GEMA) for opioid use disorder: Protocol for a just-in-time adaptive intervention (2026)
    Journal of Substance Use and Addiction Treatment DOI OpenAlex
  • Effort and Substance Use: Differentiating Tobacco Use Through Reinforcement Learning of Effort Based Decision Making (2026)
    Research Square DOI OpenAlex
  • Randomized, placebo-controlled trial of gabapentin during outpatient buprenorphine-assisted taper and transition to injectable naltrexone (2025)
    The American Journal of Drug and Alcohol Abuse 1 citation DOI OpenAlex
  • Exploratory study of heart rate variability among participants with opioid use disorder inducted on gabapentin versus placebo during outpatient buprenorphine-assisted transition to injection naltrexone. (2025)
    Experimental and Clinical Psychopharmacology DOI OpenAlex
  • Study Protocol for Implementation of Pharmacist-Led Interventions to Increase Access to Medications for Opioid Use Disorder for Incarcerated Individuals (PLI-MOUD Study) (2025)
    Substance Use &amp Addiction Journal DOI OpenAlex
  • A randomized clinical trial of disulfiram at higher doses for the treatment of cocaine use disorder among methadone-stabilized patients (2025)
    Journal of Psychiatric Research DOI OpenAlex
  • Gabapentin and D-cycloserine alone and in combination with naloxone in methadone-maintained humans responding under a naloxone novel-response discrimination procedure (2025)
    Behavioural Pharmacology DOI OpenAlex
  • Worsening trends in the frequency of methamphetamine and other stimulant use between treatment admission and discharge (2024)
    Drug and Alcohol Dependence 1 citation DOI OpenAlex
  • THE IMPACT OF FENTANYL ON TREATMENT OUTCOMES DURING AN OUTPATIENT BUPRENORPHINE TAPER WITH ADJUNCT GABAPENTIN (2024)
    Drug and Alcohol Dependence DOI OpenAlex
  • Geographic and Racial/Ethnic Differences in Access to Methamphetamine Detoxification Services, United States, 2021 (2024)
    Medical Care 4 citations DOI OpenAlex
  • 484 A Preliminary Study on the Pharmacodynamics of Oral Cannabis Ingestion in Older Adults (2024)
    Journal of Clinical and Translational Science DOI OpenAlex
  • Characteristics of patients undergoing medication-assisted treatment for opioid use disorder and their interest in Tai Chi practice (2023)
    Journal of Opioid Management DOI OpenAlex
  • 289 Heart Rate Variability in Opioid Use Disordered Participants Undergoing Buprenorphine-Assisted Detoxification (2023)
    Journal of Clinical and Translational Science DOI OpenAlex
  • Smartphone intervention to optimize medication-assisted treatment outcomes for opioid use disorder: study protocol for a randomized controlled trial (2023)
    Trials 5 citations DOI OpenAlex
  • Smartphone intervention to optimize medication assisted treatment outcomes for opioid use disorder: study protocol for a randomized controlled trial (2023)
    Research Square DOI OpenAlex

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Grants & Funding

As listed on this researcher's institutional profile.

  • Efficacy of Carvedilol in Recently-Abstinent Psychostimulant Dependent Patients NIH/Nat. Inst. on Drug Abuse via Baylor College of Medicine Co-Investigator
  • CTN-0100: Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD) NIH/Nat. Inst. on Drug Abuse via New York University Principal Investigator
  • Clinical Trials Network: The Big South/West Node NIH/Nat. Inst. on Drug Abuse via University of Texas Southwestern Medical Center Principal Investigator
  • ADAP Substance Abuse Treatment Clinic FY24 Substance Abuse & Mental Health Services Administration via Arkansas Department of Human Services Principal Investigator
  • Expanding Infant Mental Health Services in AR Substance Abuse & Mental Health Services Administration via AR Dept of Human Services/Division of Aging and Adult Services Principal Investigator
  • University of Arkansas for Medical Sciences - Substance Abuse Treatment Clinic Arkansas Department of Health & Human Services Principal Investigator
  • Improving Treatment Outcomes for Prescription Opioid Dependence - Continuation - Continuation - Continuation - Continuation NIH/Nat. Inst. on Drug Abuse Co-Principal Investigator
  • Clinical Efficacy of Lisdexamfetamine for Methamphetamine Dependence NIH Principal Investigator

Collaboration Network

50 Collaborators 16 Institutions 1 Country

Top Collaborators

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