Michael J. Mancino
CAST Program Director
Also affiliated: University of Louisville (1992–1996); University of Arkansas Medical Center (2010); Central Arkansas Veterans Healthcare System (2006–2010); Centers for Behavioral Health (2001); Azienda Usl Toscana Centro (2016–2017)
Faculty Researcher
PSY Psychiatry, College of Medicine
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Dr. Michael J. Mancino's research focuses on substance use disorders, with a particular emphasis on opioid and stimulant use. He investigates pharmacological and behavioral interventions to improve treatment outcomes for individuals with these conditions.
Dr. Mancino's work includes clinical trials examining the efficacy of medications such as buprenorphine and naltrexone for opioid use disorder. He has also studied the utility of gabapentin in managing stimulant withdrawal and supported the transition to injectable naltrexone. His research explores factors influencing treatment retention and advancement, including the impact of anxiety severity. Additionally, Dr. Mancino investigates trends in stimulant use and disparities in access to detoxification services.
His publications address the development and validation of analytical methods for quantifying medications in biological samples, crucial for pharmacokinetic and pharmacodynamic studies. Dr. Mancino's research network includes collaborators such as Alison Oliveto and Jeff D. Thostenson at the University of Arkansas for Medical Sciences. He is also the CAST Program Director at the UAMS Psychiatric Research Institute, overseeing research and treatment services for addiction.
Research Overview
Dr. Michael J. Mancino is a Professor in the UAMS Department of Psychiatry and the program director of the Center for Addiction Services and Treatment in the Psychiatric Research Institute.
Metrics
- h-index: 16
- Publications: 61
- Citations: 900
Selected Publications
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Geospatial ecological momentary assessment (GEMA) for opioid use disorder: Protocol for a just-in-time adaptive intervention (2026)
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Effort and Substance Use: Differentiating Tobacco Use Through Reinforcement Learning of Effort Based Decision Making (2026)
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Randomized, placebo-controlled trial of gabapentin during outpatient buprenorphine-assisted taper and transition to injectable naltrexone (2025)
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Exploratory study of heart rate variability among participants with opioid use disorder inducted on gabapentin versus placebo during outpatient buprenorphine-assisted transition to injection naltrexone. (2025)
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Study Protocol for Implementation of Pharmacist-Led Interventions to Increase Access to Medications for Opioid Use Disorder for Incarcerated Individuals (PLI-MOUD Study) (2025)
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A randomized clinical trial of disulfiram at higher doses for the treatment of cocaine use disorder among methadone-stabilized patients (2025)
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Gabapentin and D-cycloserine alone and in combination with naloxone in methadone-maintained humans responding under a naloxone novel-response discrimination procedure (2025)
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Worsening trends in the frequency of methamphetamine and other stimulant use between treatment admission and discharge (2024)
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THE IMPACT OF FENTANYL ON TREATMENT OUTCOMES DURING AN OUTPATIENT BUPRENORPHINE TAPER WITH ADJUNCT GABAPENTIN (2024)
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Geographic and Racial/Ethnic Differences in Access to Methamphetamine Detoxification Services, United States, 2021 (2024)
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484 A Preliminary Study on the Pharmacodynamics of Oral Cannabis Ingestion in Older Adults (2024)
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Characteristics of patients undergoing medication-assisted treatment for opioid use disorder and their interest in Tai Chi practice (2023)
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289 Heart Rate Variability in Opioid Use Disordered Participants Undergoing Buprenorphine-Assisted Detoxification (2023)
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Smartphone intervention to optimize medication-assisted treatment outcomes for opioid use disorder: study protocol for a randomized controlled trial (2023)
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Smartphone intervention to optimize medication assisted treatment outcomes for opioid use disorder: study protocol for a randomized controlled trial (2023)
Grants & Funding
As listed on this researcher's institutional profile.
- Efficacy of Carvedilol in Recently-Abstinent Psychostimulant Dependent Patients NIH/Nat. Inst. on Drug Abuse via Baylor College of Medicine Co-Investigator
- CTN-0100: Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD) NIH/Nat. Inst. on Drug Abuse via New York University Principal Investigator
- Clinical Trials Network: The Big South/West Node NIH/Nat. Inst. on Drug Abuse via University of Texas Southwestern Medical Center Principal Investigator
- ADAP Substance Abuse Treatment Clinic FY24 Substance Abuse & Mental Health Services Administration via Arkansas Department of Human Services Principal Investigator
- Expanding Infant Mental Health Services in AR Substance Abuse & Mental Health Services Administration via AR Dept of Human Services/Division of Aging and Adult Services Principal Investigator
- University of Arkansas for Medical Sciences - Substance Abuse Treatment Clinic Arkansas Department of Health & Human Services Principal Investigator
- Improving Treatment Outcomes for Prescription Opioid Dependence - Continuation - Continuation - Continuation - Continuation NIH/Nat. Inst. on Drug Abuse Co-Principal Investigator
- Clinical Efficacy of Lisdexamfetamine for Methamphetamine Dependence NIH Principal Investigator
- SOR III Carryforward Justice Involved Individuals Substance Abuse & Mental Health Services Administration via Arkansas Department of Health & Human Services Principal Investigator
- ADAP Substance Abuse Treatment Clinic - Continuation - Continuation - Continuation - Continuation - Continuation Substance Abuse & Mental Health Services Administration via Arkansas Department of Health & Human Services Principal Investigator
- Monoamine Antagonist Therapies for Methamphetamine Abuse NIH/Nat. Inst. on Drug Abuse Co-Investigator
- Impact of CYP2D6 Phenotype on Response to Methamphetamine in Humans NIH/Nat. Inst. on Drug Abuse Co-Investigator
- SOR III Emergency Department Naloxone Project Substance Abuse & Mental Health Services Administration via Arkansas Department of Human Services Principal Investigator
- SOR IV HUB and SPOKE GRANT Substance Abuse & Mental Health Services Administration via Arkansas Department of Human Services Principal Investigator
- Improving Treatment Outcomes for Prescription Opioid Dependence NIH Co-Principal Investigator
- Improving Treatment Strategies for Prescription Opioid Use Disorder- Resubmission NIH Co-Investigator
- MATRIARC Carryforward SORIII FY2024 Substance Abuse & Mental Health Services Administration via Arkansas Department of Health & Human Services Principal Investigator
- Center for Translational Neuroscience NIH Co-Investigator
- Neurocognitive Mechanisms Underlying Smartphone-Assisted Prevention of Relapse in Opioid Use Disorder NIH Co-Investigator
- SOR III MAT Training Carryover FY24 Substance Abuse & Mental Health Services Administration via Arkansas Department of Health & Human Services Principal Investigator
- AN FMRI STUDY OF THE IMPACT OF STRESS ON DRUG ADDICTION NIH/Nat. Inst. on Drug Abuse Co-Investigator
- State Opioid Response Grant for MATRIARC and ECHO Substance Abuse & Mental Health Services Administration via Arkansas Department of Human Services Principal Investigator
- Medication-Assisted Treatment Services using Opioid Use Disorder Substance Abuse & Mental Health Services Administration via Arkansas Department of Human Services Principal Investigator
- Carryover SOR III Emergency Department FY24 Substance Abuse & Mental Health Services Administration via Arkansas Department of Health & Human Services Principal Investigator
Collaboration Network
Top Collaborators
- Utility of a controlled amphetamine withdrawal paradigm among adults who use methamphetamine: A pilot clinical trial
- Development and validation of a rapid liquid chromatography/tandem mass spectrometry method to quantitate gabapentin and buprenorphine in human serum
- Impact of state and trait anxiety severity on retention and phase advancement in an outpatient buprenorphine treatment program
- 289 Heart Rate Variability in Opioid Use Disordered Participants Undergoing Buprenorphine-Assisted Detoxification
- 484 A Preliminary Study on the Pharmacodynamics of Oral Cannabis Ingestion in Older Adults
Showing 5 of 10 shared publications
- Utility of a controlled amphetamine withdrawal paradigm among adults who use methamphetamine: A pilot clinical trial
- Exploratory study of heart rate variability among participants with opioid use disorder inducted on gabapentin versus placebo during outpatient buprenorphine-assisted transition to injection naltrexone.
- Randomized, placebo-controlled trial of gabapentin during outpatient buprenorphine-assisted taper and transition to injectable naltrexone
- 289 Heart Rate Variability in Opioid Use Disordered Participants Undergoing Buprenorphine-Assisted Detoxification
- 484 A Preliminary Study on the Pharmacodynamics of Oral Cannabis Ingestion in Older Adults
- Exploratory study of heart rate variability among participants with opioid use disorder inducted on gabapentin versus placebo during outpatient buprenorphine-assisted transition to injection naltrexone.
- 484 A Preliminary Study on the Pharmacodynamics of Oral Cannabis Ingestion in Older Adults
- THE IMPACT OF FENTANYL ON TREATMENT OUTCOMES DURING AN OUTPATIENT BUPRENORPHINE TAPER WITH ADJUNCT GABAPENTIN
- A randomized clinical trial of disulfiram at higher doses for the treatment of cocaine use disorder among methadone-stabilized patients
- THE IMPACT OF FENTANYL ON TREATMENT OUTCOMES DURING AN OUTPATIENT BUPRENORPHINE TAPER WITH ADJUNCT GABAPENTIN
- Gabapentin and D-cycloserine alone and in combination with naloxone in methadone-maintained humans responding under a naloxone novel-response discrimination procedure
- Randomized, placebo-controlled trial of gabapentin during outpatient buprenorphine-assisted taper and transition to injectable naltrexone
- Clearance of buprenorphine during pregnancy and neonatal outcomes
- Impact of state and trait anxiety severity on retention and phase advancement in an outpatient buprenorphine treatment program
- Development and validation of a rapid liquid chromatography/tandem mass spectrometry method to quantitate gabapentin and buprenorphine in human serum
- Randomized, placebo-controlled trial of gabapentin during outpatient buprenorphine-assisted taper and transition to injectable naltrexone
- Utility of a controlled amphetamine withdrawal paradigm among adults who use methamphetamine: A pilot clinical trial
- Smartphone intervention to optimize medication-assisted treatment outcomes for opioid use disorder: study protocol for a randomized controlled trial
- Utility of a controlled amphetamine withdrawal paradigm among adults who use methamphetamine: A pilot clinical trial
- A randomized clinical trial of disulfiram at higher doses for the treatment of cocaine use disorder among methadone-stabilized patients
- Impact of state and trait anxiety severity on retention and phase advancement in an outpatient buprenorphine treatment program
- 484 A Preliminary Study on the Pharmacodynamics of Oral Cannabis Ingestion in Older Adults
- Smartphone intervention to optimize medication-assisted treatment outcomes for opioid use disorder: study protocol for a randomized controlled trial
- Smartphone intervention to optimize medication assisted treatment outcomes for opioid use disorder: study protocol for a randomized controlled trial
- Smartphone intervention to optimize medication-assisted treatment outcomes for opioid use disorder: study protocol for a randomized controlled trial
- Smartphone intervention to optimize medication assisted treatment outcomes for opioid use disorder: study protocol for a randomized controlled trial
- Smartphone intervention to optimize medication-assisted treatment outcomes for opioid use disorder: study protocol for a randomized controlled trial
- Smartphone intervention to optimize medication assisted treatment outcomes for opioid use disorder: study protocol for a randomized controlled trial
- Smartphone intervention to optimize medication-assisted treatment outcomes for opioid use disorder: study protocol for a randomized controlled trial
- Smartphone intervention to optimize medication assisted treatment outcomes for opioid use disorder: study protocol for a randomized controlled trial
- Smartphone intervention to optimize medication-assisted treatment outcomes for opioid use disorder: study protocol for a randomized controlled trial
- Smartphone intervention to optimize medication assisted treatment outcomes for opioid use disorder: study protocol for a randomized controlled trial
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