Match tier
Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-15
J
Jeff D. Thostenson
Biostatistician II
Also affiliated: Cancer Research And Biostatistics (2023); Institute for Musculoskeletal Health (2024)
Faculty Researcher
16 h-index
48 pubs
1,824 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Jeff D. Thostenson's research focuses on bone metabolism and resorption, investigating the molecular mechanisms that regulate these processes. His work has explored the role of osteocytes in bone resorption, particularly in the context of denosumab discontinuation, and has examined the impact of mitochondrial protein deacetylation by SIRT3 in osteoclasts on bone resorption with aging in female mice. Thostenson has also studied the effects of Tfeb elevation in osteoblast lineage cells on bone mass and strength, and investigated alterations in type I collagen that lead to lung and respiratory defects in mouse models of osteogenesis imperfecta. His research interests also extend to clinical areas, including predictors of no-show appointments in neurology clinics and the utility of controlled amphetamine withdrawal paradigms for individuals using methamphetamine. Thostenson has contributed to 46 publications, with a total of 1,784 citations and an h-index of 16. He has collaborated with researchers at the University of Arkansas for Medical Sciences, including Charles A. O’Brien, Joseph J. Goellner, Elena Ambrogini, and Qiang Fu.
Metrics
- h-index: 16
- Publications: 48
- Citations: 1,824
Selected Publications
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DMP1-Cre expressing cells mediate the gain in bone mass and strength, but not the increase in bone remodeling, induced by ligands of the parathyroid hormone receptor (2026)
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Beyond contextual smoking norms: The importance of family-level nicotine use risk factors among rural and nonrural youth living in Arkansas (2026)
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Dissecting primary versus secondary effects of osteogenesis imperfecta on abnormal lung development and function (2026)
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Randomized, placebo-controlled trial of gabapentin during outpatient buprenorphine-assisted taper and transition to injectable naltrexone (2025)
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Discontinuation of levothyroxine therapy in patients with subclinical hypothyroidism: a pilot randomized clinical trial (2025)
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Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength (2025)
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Exploratory study of heart rate variability among participants with opioid use disorder inducted on gabapentin versus placebo during outpatient buprenorphine-assisted transition to injection naltrexone. (2025)
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Potent suppression of bone remodeling by denosumab does not blunt the anabolic response to romosozumab in mice (2025)
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Sirtuin-3 promotes osteoclast maturation and bone loss by regulating mitochondrial ROS production during ionizing radiation exposure (2025)
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A randomized clinical trial of disulfiram at higher doses for the treatment of cocaine use disorder among methadone-stabilized patients (2025)
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Plasma levels of anti phosphocholine IgM antibodies are negatively correlated with bone mineral density in humans (2025)
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A Predictive Model for Graves’ Disease Recurrence After Antithyroid Drug Therapy: A Retrospective Multicenter Cohort Study (2024)
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A new <i>Col1a1</i> conditional knock-in mouse model to study osteogenesis imperfecta (2024)
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CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength (2024)
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Frequency and Determinants of Levothyroxine Therapy Initiation for Veterans with Subclinical Hypothyroidism (2024)
Collaboration Network
Top Collaborators
Alison Oliveto
University of Arkansas for Medical Sciences
7 shared publications
In database
- Utility of a controlled amphetamine withdrawal paradigm among adults who use methamphetamine: A pilot clinical trial
- Randomized, placebo-controlled trial of gabapentin during outpatient buprenorphine-assisted taper and transition to injectable naltrexone
- 484 A Preliminary Study on the Pharmacodynamics of Oral Cannabis Ingestion in Older Adults
- CANNABINOID-INVOLVED EXPOSURES, ED VISITS AND HOSPITALIZATIONS BEFORE AND AFTER ARKANSAS MEDICAL MARIJUANA LAW ENACTMENT: INITIAL TRENDS
- THE IMPACT OF FENTANYL ON TREATMENT OUTCOMES DURING AN OUTPATIENT BUPRENORPHINE TAPER WITH ADJUNCT GABAPENTIN
Showing 5 of 7 shared publications
Michael J. Mancino
University of Arkansas for Medical Sciences
6 shared publications
In database
- Utility of a controlled amphetamine withdrawal paradigm among adults who use methamphetamine: A pilot clinical trial
- Randomized, placebo-controlled trial of gabapentin during outpatient buprenorphine-assisted taper and transition to injectable naltrexone
- 484 A Preliminary Study on the Pharmacodynamics of Oral Cannabis Ingestion in Older Adults
- THE IMPACT OF FENTANYL ON TREATMENT OUTCOMES DURING AN OUTPATIENT BUPRENORPHINE TAPER WITH ADJUNCT GABAPENTIN
- A randomized clinical trial of disulfiram at higher doses for the treatment of cocaine use disorder among methadone-stabilized patients
Showing 5 of 6 shared publications
Melda Onal
Institute for Musculoskeletal Health
5 shared publications
In database
- Deletion of a putative promoter-proximal Tnfsf11 regulatory region in mice does not alter bone mass or Tnfsf11 expression in vivo
- CRISPR interference provides increased cell type-specificity compared to the Cre-loxP system
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- A new <i>Col1a1</i> conditional knock-in mouse model to study osteogenesis imperfecta
- CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
Charles A. O’Brien
University of Arkansas for Medical Sciences
5 shared publications
In database
- Reduced osteoprotegerin expression by osteocytes may contribute to rebound resorption after denosumab discontinuation
- Deletion of a putative promoter-proximal Tnfsf11 regulatory region in mice does not alter bone mass or Tnfsf11 expression in vivo
- CRISPR interference provides increased cell type-specificity compared to the Cre-loxP system
- A new <i>Col1a1</i> conditional knock-in mouse model to study osteogenesis imperfecta
- Potent suppression of bone remodeling by denosumab does not blunt the anabolic response to romosozumab in mice
Spyridoula Maraka
Central Arkansas Veterans Healthcare System
4 shared publications
In database
- A Predictive Model for Graves’ Disease Recurrence After Antithyroid Drug Therapy: A Retrospective Multicenter Cohort Study
- Discontinuation of levothyroxine therapy in patients with subclinical hypothyroidism: a pilot randomized clinical trial
- Frequency and Determinants of Levothyroxine Therapy Initiation for Veterans with Subclinical Hypothyroidism
- Plasma levels of anti phosphocholine IgM antibodies are negatively correlated with bone mineral density in humans
Jinhu Xiong
University of Arkansas for Medical Sciences
3 shared publications
In database
- Deletion of a putative promoter-proximal Tnfsf11 regulatory region in mice does not alter bone mass or Tnfsf11 expression in vivo
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- Dissecting primary versus secondary effects of osteogenesis imperfecta on abnormal lung development and function
Mark Mennemeier
University of Arkansas for Medical Sciences
3 shared publications
In database
- Change in EEG Activity is Associated with a Decrease in Tinnitus Awareness after rTMS.
- On How Psychophysical Thresholds are Altered by Unilateral Brain Injury Due to Stroke
- BRAIN STIMULATION CAN AUGMENT AN EFFECTIVE BEHAVIORAL TREATMENT WITH VAGINAL TRAINERS FOR LIFELONG VAGINISMUS: A RANDOMIZED CONTROLLED TRIAL
Milena Dimori
University of Arkansas for Medical Sciences
3 shared publications
In database
- Distinct type I collagen alterations cause intrinsic lung and respiratory defects of variable severity in mouse models of osteogenesis imperfecta
- A new <i>Col1a1</i> conditional knock-in mouse model to study osteogenesis imperfecta
- Dissecting primary versus secondary effects of osteogenesis imperfecta on abnormal lung development and function
John L. Carroll
University of Arkansas for Medical Sciences
3 shared publications
In database
- Distinct type I collagen alterations cause intrinsic lung and respiratory defects of variable severity in mouse models of osteogenesis imperfecta
- A new <i>Col1a1</i> conditional knock-in mouse model to study osteogenesis imperfecta
- Dissecting primary versus secondary effects of osteogenesis imperfecta on abnormal lung development and function
Roy Morello
University of Arkansas for Medical Sciences
3 shared publications
In database
- Distinct type I collagen alterations cause intrinsic lung and respiratory defects of variable severity in mouse models of osteogenesis imperfecta
- A new <i>Col1a1</i> conditional knock-in mouse model to study osteogenesis imperfecta
- Dissecting primary versus secondary effects of osteogenesis imperfecta on abnormal lung development and function
James A. Hendrixson
University of Arkansas for Medical Sciences
3 shared publications
In database
- CRISPR interference provides increased cell type-specificity compared to the Cre-loxP system
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
Julie Crawford
Institute for Musculoskeletal Health
3 shared publications
In database
- CRISPR interference provides increased cell type-specificity compared to the Cre-loxP system
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
- CRISPR activation of <i>Tfeb</i> , a master regulator of autophagy and lysosomal biogenesis, in osteoblast lineage cells increases bone mass and strength
Intawat Nookaew
Institute for Musculoskeletal Health
3 shared publications
In database
- Reduced osteoprotegerin expression by osteocytes may contribute to rebound resorption after denosumab discontinuation
- CRISPR interference provides increased cell type-specificity compared to the Cre-loxP system
- Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength
Qiang Fu
University of Arkansas for Medical Sciences
3 shared publications
In database
- Reduced osteoprotegerin expression by osteocytes may contribute to rebound resorption after denosumab discontinuation
- Potent suppression of bone remodeling by denosumab does not blunt the anabolic response to romosozumab in mice
- Sirtuin-3 promotes osteoclast maturation and bone loss by regulating mitochondrial ROS production during ionizing radiation exposure
Elena Ambrogini
Central Arkansas Veterans Healthcare System
3 shared publications
In database
- Reduced osteoprotegerin expression by osteocytes may contribute to rebound resorption after denosumab discontinuation
- Discontinuation of levothyroxine therapy in patients with subclinical hypothyroidism: a pilot randomized clinical trial
- Plasma levels of anti phosphocholine IgM antibodies are negatively correlated with bone mineral density in humans
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