Match tier
Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-05
Biography and Research Information
OverviewAI-generated summary
Rajshekar A. Kore investigates the role of exosomes and cellular communication in disease processes, with a particular focus on cancer and cardiovascular conditions. His research has explored how exosomes, secreted by various cell types including tumor cells and mesenchymal stem cells, can influence disease progression and therapeutic response. This includes studying the impact of exosomal content, such as inflammatory cytokines and proteins like CRYAB, on glioblastoma cells and examining the cardioprotective effects of mesenchymal stem cell-derived exosomes in models of ischemic heart disease. Kore has also examined the mechanisms of exosome secretion and the regulation of specific proteins within these vesicles. Additionally, his work touches upon the therapeutic potential of targeting metabolic pathways in cancer, such as the inhibition of glutaminase, and has contributed to reviews on therapies for chronic kidney disease.
Metrics
- h-index: 1
- Publications: 3
- Citations: 1
Positions
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Instructor publications 2020–2026University of Arkansas for Medical Sciences Internal Medicine ORCID
Selected Publications
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Hydrocortisone Use for Septic Shock in Patients With CKD (2026)
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Abstract 7625: Development of a blood-based tumor hypoxia detection assay (2026)
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Higher Glycolysis in Circulating Leukocytes in Patients with CKD (2024)
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Platelets, inflammation, and purinergic receptors in chronic kidney disease (2024)
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Abstract 186: Tumor exosome-macrophage interactions: The role of tumor-associated glycans and scavenger receptor class A (2024)
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Authors' Reply: Platelet Count, Platelet Volume and CKD (2024)
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Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain (2023)
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Updates on New Therapies for Patients with CKD (2023)
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Platelet Count and Platelet Volume in Patients with CKD (2023)
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Proteomic analysis of transcription factors involved in the alteration of ischemic mouse heart as modulated by MSC exosomes (2023)
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Proteomic Analysis of Transcription Factors Involved in the Alteration of Ischemic Mouse Heart as Modulated by MSC Exosomes (2023)
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Mesenchymal Stem Cell Treatment for Hyperactive Immune Response in Patients with COVID-19 (2022)
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Author Correction: Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes (2022)
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The Structural Basis of Effective LOX-1 Inhibition (2022)
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Proteomic basis of modulation of postischemic fibrosis by MSC exosomes (2021)
Collaboration Network
Top Collaborators
Robert J. Griffin
University of Arkansas for Medical Sciences
16 shared publications
In database
- Glutaminase inhibitor CB-839 increases radiation sensitivity of lung tumor cells and human lung tumor xenografts in mice
- Hypoxia-derived exosomes induce putative altered pathways in biosynthesis and ion regulatory channels in glioblastoma cells
- Modulation of dietary methionine intake elicits potent, yet distinct, anticancer effects on primary versus metastatic tumors
- MSC exosome-mediated cardioprotection in ischemic mouse heart comparative proteomics of infarct and peri-infarct areas
- Modifying Dendritic Cell Activation with Plasmonic Nano Vectors
Showing 5 of 16 shared publications
Azemat Jamshidi‐Parsian
University of Arkansas for Medical Sciences
10 shared publications
In database
- Glutaminase inhibitor CB-839 increases radiation sensitivity of lung tumor cells and human lung tumor xenografts in mice
- Hypoxia-derived exosomes induce putative altered pathways in biosynthesis and ion regulatory channels in glioblastoma cells
- Modulation of dietary methionine intake elicits potent, yet distinct, anticancer effects on primary versus metastatic tumors
- In VivoFlow Cytometry of Circulating Tumor-Associated Exosomes
- Tumor-endothelial cell interaction in an experimental model of human hepatocellular carcinoma
Showing 5 of 10 shared publications
Zufeng Ding
Central Arkansas Veterans Healthcare System (US)
7 shared publications
- NLRP3 inflammasome via IL-1β regulates PCSK9 secretion
- MSC exosome-mediated cardioprotection in ischemic mouse heart comparative proteomics of infarct and peri-infarct areas
- Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes
- Proteomic basis of modulation of postischemic fibrosis by MSC exosomes
- Author Correction: Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes
Showing 5 of 7 shared publications
Jawahar L. Mehta
Central Arkansas Veterans Healthcare System
7 shared publications
In database
- NLRP3 inflammasome via IL-1β regulates PCSK9 secretion
- MSC exosome-mediated cardioprotection in ischemic mouse heart comparative proteomics of infarct and peri-infarct areas
- Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes
- Platelet Count and Platelet Volume in Patients with CKD
- Author Correction: Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes
Showing 5 of 7 shared publications
Jawahar L. Mehta
Central Arkansas Veterans Healthcare System
6 shared publications
In database
- Updates on New Therapies for Patients with CKD
- Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain
- Proteomic basis of modulation of postischemic fibrosis by MSC exosomes
- Mesenchymal Stem Cell Treatment for Hyperactive Immune Response in Patients with COVID-19
- The Structural Basis of Effective LOX-1 Inhibition
Showing 5 of 6 shared publications
Nishank Jain
University of Arkansas for Medical Sciences
6 shared publications
In database
- Updates on New Therapies for Patients with CKD
- Platelets, inflammation, and purinergic receptors in chronic kidney disease
- Platelet Count and Platelet Volume in Patients with CKD
- Authors' Reply: Platelet Count, Platelet Volume and CKD
- Higher Glycolysis in Circulating Leukocytes in Patients with CKD
Showing 5 of 6 shared publications
Alan J. Tackett
University of Arkansas for Medical Sciences
5 shared publications
In database
- MSC exosome-mediated cardioprotection in ischemic mouse heart comparative proteomics of infarct and peri-infarct areas
- Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes
- Author Correction: Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes
- Proteomic Analysis of Transcription Factors Involved in the Alteration of Ischemic Mouse Heart as Modulated by MSC Exosomes
- Proteomic analysis of transcription factors involved in the alteration of ischemic mouse heart as modulated by MSC exosomes
Edathara C. Abraham
University of Arkansas for Medical Sciences (US)
4 shared publications
- Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells
- Phosphorylation negatively regulates exosome mediated secretion of cryAB in glioma cells
- Quaternary structural parameters of the congenital cataract causing mutants of αA-crystallin
- Exosomes Secreted by Inflammatory Cytokine Stimulated Glioma Cells Carry a Repertoire of Proteins Which Influence Progression of Glioblastoma Multiforme
Samir V. Jenkins
University of Arkansas for Medical Sciences
4 shared publications
In database
- Hypoxia-derived exosomes induce putative altered pathways in biosynthesis and ion regulatory channels in glioblastoma cells
- Proteomic Analysis of Transcription Factors Involved in the Alteration of Ischemic Mouse Heart as Modulated by MSC Exosomes
- Proteomic analysis of transcription factors involved in the alteration of ischemic mouse heart as modulated by MSC exosomes
- Abstract 186: Tumor exosome-macrophage interactions: The role of tumor-associated glycans and scavenger receptor class A
Rabab N. Hamzah
University of Arkansas at Little Rock
4 shared publications
In database
- Glioma-derived exosomes drive the differentiation of neural stem cells to astrocytes
- Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes
- Author Correction: Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes
- Exosomes as Naturally Occurring, Abundant Nanoscale Soft Materials: Potential as Biomarkers and Delivery Vehicles for Solving Biomedical Problems
Xianwei Wang
Henan Medical University (CN)
4 shared publications
- NLRP3 inflammasome via IL-1β regulates PCSK9 secretion
- MSC exosome-mediated cardioprotection in ischemic mouse heart comparative proteomics of infarct and peri-infarct areas
- Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain
- Proteomic basis of modulation of postischemic fibrosis by MSC exosomes
Ruud P.M. Dings
Winthrop Rockefeller Foundation
3 shared publications
In database
- Glutaminase inhibitor CB-839 increases radiation sensitivity of lung tumor cells and human lung tumor xenografts in mice
- Hypoxia-derived exosomes induce putative altered pathways in biosynthesis and ion regulatory channels in glioblastoma cells
- Modifying Dendritic Cell Activation with Plasmonic Nano Vectors
J. Curran Henson
Central Arkansas Veterans Healthcare System
3 shared publications
In database
- Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes
- Proteomic basis of modulation of postischemic fibrosis by MSC exosomes
- Author Correction: Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes
Srinivas Ayyadevara
University of Arkansas Medical Center
3 shared publications
In database
- Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain
- Proteomic Analysis of Transcription Factors Involved in the Alteration of Ischemic Mouse Heart as Modulated by MSC Exosomes
- Proteomic analysis of transcription factors involved in the alteration of ischemic mouse heart as modulated by MSC exosomes
John M. Arthur
Central Arkansas Veterans Healthcare System
3 shared publications
In database
- Platelet Count and Platelet Volume in Patients with CKD
- Authors' Reply: Platelet Count, Platelet Volume and CKD
- Hydrocortisone Use for Septic Shock in Patients With CKD
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