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Biography and Research Information
OverviewAI-generated summary
Richard C. Kurten's research focuses on understanding the molecular and cellular mechanisms underlying various human and animal diseases, with a particular emphasis on respiratory and gastrointestinal conditions. His work investigates the roles of specific proteins, cytokines, and cellular processes in disease pathogenesis and potential therapeutic interventions.
Recent publications demonstrate his engagement with diverse research areas. These include studies on mucin packaging within secretory granules, the function of the cytokine LIGHT in esophageal fibroblasts related to eosinophilic esophagitis, and the impact of ORMDL3 expression on airway smooth muscle. Kurten has also explored the use of a human precision-cut lung slice platform for investigating SARS-CoV-2 pathogenesis and antiviral drug efficacy, as well as the effects of rhinovirus on human airways. Additionally, his research has touched upon the targeting of neurotransmitter systems to inhibit the growth of *Coxiella burnetii*.
Kurten maintains an active research laboratory and collaborates with colleagues at the University of Arkansas for Medical Sciences, including Joshua L. Kennedy, Priyangi A. Malaviarachchi, Duah Alkam, and Srijon K. Banerjee. His scholarly output is reflected in a h-index of 31, with over 123 publications and more than 3,500 citations, designating him as a highly cited researcher.
Metrics
- h-index: 31
- Publications: 123
- Citations: 3,616
Selected Publications
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An <i>ex vivo</i> human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy (2024)
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Mechanotransduction-induced interplay between phospholamban and yes-activated protein induces smooth muscle cell hypertrophy (2024)
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Rhinovirus C15 Attenuates Relaxation and cAMP Production in Human Airways and Smooth Muscle (2023)
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An <i>ex vivo</i> human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy (2023)
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A Deficiency in the Cytokine TNFSF14/LIGHT Limits Inflammation and Remodeling in Murine Eosinophilic Esophagitis (2022)
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Mucin Expression in Human Precision-Cut Lung Slices (2022)
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Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules (2022)
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Reduced AIBP expression in bronchial epithelial cells of asthmatic patients: Potential therapeutic target (2022)
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Esophageal Fibroblasts are the Players in the Interferon Response in Eosinophilic Esophagitis (2022)
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LIGHT controls distinct homeostatic and inflammatory gene expression profiles in esophageal fibroblasts via differential HVEM and LTβR-mediated mechanisms (2021)
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Neurotransmitter System-Targeting Drugs Antagonize Growth of the Q Fever Agent, Coxiella burnetii, in Human Cells (2021)
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ORMDL3 expression in ASM regulates hypertrophy, hyperplasia via TPM1 and TPM4, and contractility (2021)
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Integrative Proteomics and Phosphoproteomics of Asthmatic Airways following RV Infection (2021)
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A unique esophageal extracellular matrix proteome alters normal fibroblast function in severe eosinophilic esophagitis (2021)
Collaboration Network
Top Collaborators
- A unique esophageal extracellular matrix proteome alters normal fibroblast function in severe eosinophilic esophagitis
- LIGHT controls distinct homeostatic and inflammatory gene expression profiles in esophageal fibroblasts via differential HVEM and LTβR-mediated mechanisms
- A Deficiency in the Cytokine TNFSF14/LIGHT Limits Inflammation and Remodeling in Murine Eosinophilic Esophagitis
- Mechanotransduction-induced interplay between phospholamban and yes-activated protein induces smooth muscle cell hypertrophy
- Esophageal Fibroblasts are the Players in the Interferon Response in Eosinophilic Esophagitis
Showing 5 of 7 shared publications
- A unique esophageal extracellular matrix proteome alters normal fibroblast function in severe eosinophilic esophagitis
- LIGHT controls distinct homeostatic and inflammatory gene expression profiles in esophageal fibroblasts via differential HVEM and LTβR-mediated mechanisms
- Mechanotransduction-induced interplay between phospholamban and yes-activated protein induces smooth muscle cell hypertrophy
- Esophageal Fibroblasts are the Players in the Interferon Response in Eosinophilic Esophagitis
- S100A4 Levels in Pediatric Eosinophilic Esophagitis Cohort
Showing 5 of 6 shared publications
- A unique esophageal extracellular matrix proteome alters normal fibroblast function in severe eosinophilic esophagitis
- LIGHT controls distinct homeostatic and inflammatory gene expression profiles in esophageal fibroblasts via differential HVEM and LTβR-mediated mechanisms
- Mechanotransduction-induced interplay between phospholamban and yes-activated protein induces smooth muscle cell hypertrophy
- Esophageal Fibroblasts are the Players in the Interferon Response in Eosinophilic Esophagitis
- S100A4 Levels in Pediatric Eosinophilic Esophagitis Cohort
Showing 5 of 6 shared publications
- An <i>ex vivo</i> human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy
- An <i>ex vivo</i> human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy
- Eosinophilic esophagitis drives tissue fibroblast regenerative programs toward pathologic dysfunction
- Integrative Proteomics and Phosphoproteomics of Asthmatic Airways following RV Infection
- LIGHT controls distinct homeostatic and inflammatory gene expression profiles in esophageal fibroblasts via differential HVEM and LTβR-mediated mechanisms
- A Deficiency in the Cytokine TNFSF14/LIGHT Limits Inflammation and Remodeling in Murine Eosinophilic Esophagitis
- Esophageal Fibroblasts are the Players in the Interferon Response in Eosinophilic Esophagitis
- Eosinophilic esophagitis drives tissue fibroblast regenerative programs toward pathologic dysfunction
- LIGHT controls distinct homeostatic and inflammatory gene expression profiles in esophageal fibroblasts via differential HVEM and LTβR-mediated mechanisms
- A Deficiency in the Cytokine TNFSF14/LIGHT Limits Inflammation and Remodeling in Murine Eosinophilic Esophagitis
- Mechanotransduction-induced interplay between phospholamban and yes-activated protein induces smooth muscle cell hypertrophy
- Eosinophilic esophagitis drives tissue fibroblast regenerative programs toward pathologic dysfunction
- A unique esophageal extracellular matrix proteome alters normal fibroblast function in severe eosinophilic esophagitis
- LIGHT controls distinct homeostatic and inflammatory gene expression profiles in esophageal fibroblasts via differential HVEM and LTβR-mediated mechanisms
- Mechanotransduction-induced interplay between phospholamban and yes-activated protein induces smooth muscle cell hypertrophy
- A unique esophageal extracellular matrix proteome alters normal fibroblast function in severe eosinophilic esophagitis
- Mechanotransduction-induced interplay between phospholamban and yes-activated protein induces smooth muscle cell hypertrophy
- Eosinophilic esophagitis drives tissue fibroblast regenerative programs toward pathologic dysfunction
- An <i>ex vivo</i> human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy
- An <i>ex vivo</i> human precision-cut lung slice platform provides insight into SARS-CoV-2 pathogenesis and antiviral drug efficacy
- Integrative Proteomics and Phosphoproteomics of Asthmatic Airways following RV Infection
- LIGHT controls distinct homeostatic and inflammatory gene expression profiles in esophageal fibroblasts via differential HVEM and LTβR-mediated mechanisms
- A Deficiency in the Cytokine TNFSF14/LIGHT Limits Inflammation and Remodeling in Murine Eosinophilic Esophagitis
- Eosinophilic esophagitis drives tissue fibroblast regenerative programs toward pathologic dysfunction
- A unique esophageal extracellular matrix proteome alters normal fibroblast function in severe eosinophilic esophagitis
- S100A4 Levels in Pediatric Eosinophilic Esophagitis Cohort
- A unique esophageal extracellular matrix proteome alters normal fibroblast function in severe eosinophilic esophagitis
- S100A4 Levels in Pediatric Eosinophilic Esophagitis Cohort
- ORMDL3 expression in ASM regulates hypertrophy, hyperplasia via TPM1 and TPM4, and contractility
- Reduced AIBP expression in bronchial epithelial cells of asthmatic patients: Potential therapeutic target
- ORMDL3 expression in ASM regulates hypertrophy, hyperplasia via TPM1 and TPM4, and contractility
- Reduced AIBP expression in bronchial epithelial cells of asthmatic patients: Potential therapeutic target
- ORMDL3 expression in ASM regulates hypertrophy, hyperplasia via TPM1 and TPM4, and contractility
- Reduced AIBP expression in bronchial epithelial cells of asthmatic patients: Potential therapeutic target
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