Match tier
Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-09
S
Spyridoula Maraka
Federal Grant PI
High Impact
Associate Professor
Also affiliated: Mayo Clinic (2014–2025); University of Connecticut (2012–2016); University of Arkansas Medical Center (2019–2023); Central Arkansas Veterans Healthcare System (2017–2026); UConn Health (2012–2016)
Internal Med, College of Medicine
32 h-index
137 pubs
3,986 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Spyridoula Maraka's research program focuses on improving patient-centered, evidence-based endocrine care. Her work specifically investigates outcome analysis, evidence synthesis, decision-making processes, and health services delivery, with a primary emphasis on subclinical hypothyroidism. She has received funding from the NIH as PI for two awards: one investigating the discontinuation of levothyroxine therapy for patients with subclinical hypothyroidism through a pilot randomized controlled study, and another focused on minimizing levothyroxine overuse.
Her scholarly output includes 137 publications with 3,972 citations, contributing to a high-impact researcher designation. Recent publications explore themes such as subclinical hypothyroidism in pregnancy, the association between maternal thyroid function and gestational hypertension, and the effects of sex steroids on cardiovascular outcomes and bone health in transgender individuals. She also has a systematic review and meta-analysis on the outcomes of parathyroidectomy for primary hyperparathyroidism.
Maraka collaborates with several colleagues at the University of Arkansas for Medical Sciences, including Arwa Albashaireh and Richard R. Owen, with whom she has co-authored four publications. She leads a research group and is recognized as a federal grant principal investigator.
Research Overview
Clinical Practice: General endocrinology with emphasis on thyroid disorders Research Interests: Promotion of patient-centered, evidence based endocrine care through a research program focusing on outcome analysis, evidence synthesis, decision making, and health services delivery. Main focus: subclinical hypothyroidism.
Metrics
- h-index: 32
- Publications: 137
- Citations: 3,986
Positions
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Associate Professor publications 2017–2026University of Arkansas for Medical Sciences Internal Med, College of Medicine Institutional directory
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Central Arkansas Veterans Healthcare System John L McClellan Memorial Veterans HospitalMedicine ORCID
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Assistant Professor of Medicine publications 2017–2026UAMS Medical Center Medicine ORCID
Selected Publications
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Management of hyperthyroidism in pregnancy (2026)
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American Thyroid Association 2026 Guidelines for Thyroid Disease in Preconception, Pregnancy, and Postpartum (2026)
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Use of a capillary blood collection device to monitor exposure to per- and polyfluoroalkyl substances (PFAS) in Veterans living in proximity to potential sources of environmental contamination (2026)
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A comparison of bilateral internal jugular vein sampling with bilateral inferior petrosal sinus sampling at Mayo Clinic for the subtype evaluation of corticotropin-dependent cushing syndrome (2025)
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Do all superheroes wear capes? A case–control study of the highest grossing superhero movies (2025)
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Discontinuation of levothyroxine therapy in patients with subclinical hypothyroidism: a pilot randomized clinical trial (2025)
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Levothyroxine in Pregnancy: Protective Neurodevelopmental Role Beyond Cognitive Outcomes? (2025)
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Risk Factors for Thyroid Function Test Abnormalities During Pregnancy: A Systematic Review of the Literature to Validate Current Risk Factors and Identify Novel Ones (2025)
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Plasma levels of anti phosphocholine IgM antibodies are negatively correlated with bone mineral density in humans (2025)
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Frequency and Determinants of Levothyroxine Therapy Initiation for Veterans with Subclinical Hypothyroidism (2024)
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Subclinical Hypothyroidism and Thyroid Autoimmunity in Pregnancy (2024)
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Interventions to improve symptomatology in patients with hypothyroidism and persistent symptoms: A systematic review (2024)
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Risk Factors for Thyroid Dysfunction in Pregnancy: An Individual Participant Data Meta-Analysis (2024)
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Thyroid storm in pregnancy: a review (2024)
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Trends and Components of Thyroid Status Evaluation in Commercially Insured Adults in the United States, 2006-2020 (2023)
Federal Grants 2
VA
Contact PI
Jun 2025 - May 2029
Research Interests
Research Interests: Promotion of patient-centered, evidence based endocrine care through a research program focusing on outcome analysis, evidence synthesis, decision making, and health services delivery. Main focus: subclinical hypothyroidism.
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- Role of Natural Antibodies Against Oxidation Specific Epitopes in Bone Homeostasis VA Biomedical Laboratory Research and Development Merit Review Award Co-Investigator
- Subclinical hypothyroidism: a research career development plan Arkansas Biosciences Institute Principal Investigator
- Correlation of Bone Mineral Density with Anti-oxidation Specific Epitopes (anti-OSEs) Antibody levels South Central VA Health Care Network Principal Investigator
Collaboration Network
Top Collaborators
Juan P. Brito
Mayo Clinic in Arizona (US)
29 shared publications
- Thyroid hormone treatment among pregnant women with subclinical hypothyroidism: US national assessment
- Patterns of Use, Efficacy, and Safety of Treatment Options for Patients with Graves' Disease: A Nationwide Population-Based Study
- Levothyroxine Use in the United States, 2008-2018
- Benefits and Harms of Levothyroxine/L-Triiodothyronine Versus Levothyroxine Monotherapy for Adult Patients with Hypothyroidism: Systematic Review and Meta-Analysis
- Clinical Outcomes After Discontinuation of Thyroid Hormone Replacement: A Systematic Review and Meta-Analysis
Showing 5 of 29 shared publications
Naykky Singh Ospina
University of Florida (US)
20 shared publications
- Thyroid hormone treatment among pregnant women with subclinical hypothyroidism: US national assessment
- Effect of Sex Steroids on the Bone Health of Transgender Individuals: A Systematic Review and Meta-Analysis
- Subclinical Hypothyroidism in Women Planning Conception and During Pregnancy: Who Should Be Treated and How?
- Ultrasound Image Classification of Thyroid Nodules Using Machine Learning Techniques
- Clinical Outcomes After Discontinuation of Thyroid Hormone Replacement: A Systematic Review and Meta-Analysis
Showing 5 of 20 shared publications
Naykky Singh Ospina
University of Florida Health (US)
15 shared publications
- Sex Steroids and Cardiovascular Outcomes in Transgender Individuals: A Systematic Review and Meta-Analysis
- Patterns of Use, Efficacy, and Safety of Treatment Options for Patients with Graves' Disease: A Nationwide Population-Based Study
- Benefits and Harms of Levothyroxine/L-Triiodothyronine Versus Levothyroxine Monotherapy for Adult Patients with Hypothyroidism: Systematic Review and Meta-Analysis
- Inappropriate use of thyroid ultrasound: a systematic review and meta-analysis
- Effect of metformin on microvascular outcomes in patients with type 2 diabetes: A systematic review and meta-analysis
Showing 5 of 15 shared publications
René Rodríguez‐Gutiérrez
Universidad Autónoma de Nuevo León (MX)
14 shared publications
- Sex Steroids and Cardiovascular Outcomes in Transgender Individuals: A Systematic Review and Meta-Analysis
- Thyroid hormone treatment among pregnant women with subclinical hypothyroidism: US national assessment
- Effect of Sex Steroids on the Bone Health of Transgender Individuals: A Systematic Review and Meta-Analysis
- Patterns of Use, Efficacy, and Safety of Treatment Options for Patients with Graves' Disease: A Nationwide Population-Based Study
- Benefits and Harms of Levothyroxine/L-Triiodothyronine Versus Levothyroxine Monotherapy for Adult Patients with Hypothyroidism: Systematic Review and Meta-Analysis
Showing 5 of 14 shared publications
Freddy J.K. Toloza
National Institute of Diabetes and Digestive and Kidney Diseases
14 shared publications
In database
- Consequences of Severe Iodine Deficiency in Pregnancy: Evidence in Humans
- Clinical Outcomes After Discontinuation of Thyroid Hormone Replacement: A Systematic Review and Meta-Analysis
- Association of Thyroid Function with Suicidal Behavior: A Systematic Review and Meta-Analysis
- Subclinical hypothyroidism in pregnancy
- Association of Thyroid Function with Posttraumatic Stress Disorder: a Systematic Review and Meta-Analysis
Showing 5 of 14 shared publications
Derek T. O’Keeffe
Ollscoil na Gaillimhe – University of Galway (IE)
13 shared publications
- Thyroid hormone treatment among pregnant women with subclinical hypothyroidism: US national assessment
- Subclinical Hypothyroidism in Women Planning Conception and During Pregnancy: Who Should Be Treated and How?
- Ultrasound Image Classification of Thyroid Nodules Using Machine Learning Techniques
- Practice Variation in the Care of Subclinical Hypothyroidism During Pregnancy: A National Survey of Physicians in the United States
- Variation in treatment practices for subclinical hypothyroidism in pregnancy: US national assessment
Showing 5 of 13 shared publications
Víctor M. Montori
Mayo Clinic in Florida (US)
9 shared publications
- Thyroid hormone treatment among pregnant women with subclinical hypothyroidism: US national assessment
- Patterns of Use, Efficacy, and Safety of Treatment Options for Patients with Graves' Disease: A Nationwide Population-Based Study
- Practice Variation in the Care of Subclinical Hypothyroidism During Pregnancy: A National Survey of Physicians in the United States
- Variation in treatment practices for subclinical hypothyroidism in pregnancy: US national assessment
- Knowledge, Attitudes, Beliefs, and Treatment Burden Related to the Use of Levothyroxine in Hypothyroid Pregnant Women in the United States
Showing 5 of 9 shared publications
Yuanjie Mao
Ohio University (US)
6 shared publications
- Association of Thyroid Function with Suicidal Behavior: A Systematic Review and Meta-Analysis
- Association of Thyroid Function with Posttraumatic Stress Disorder: a Systematic Review and Meta-Analysis
- A novel MEN1 gene mutation associated with a pancreatic neuroendocrine tumor co-producing insulin and vasoactive intestinal polypeptide
- Plasma levels of anti phosphocholine IgM antibodies are negatively correlated with bone mineral density in humans
- MON-328 Twenty-Year Follow-Up of a Patient with a Novel MEN1 Gene Mutation
Showing 5 of 6 shared publications
Richard R. Owen
Central Arkansas Veterans Healthcare System
6 shared publications
In database
- Association of Thyroid Function with Suicidal Behavior: A Systematic Review and Meta-Analysis
- Association of Thyroid Function with Posttraumatic Stress Disorder: a Systematic Review and Meta-Analysis
- Discontinuation of levothyroxine therapy in patients with subclinical hypothyroidism: a pilot randomized clinical trial
- Frequency and Determinants of Levothyroxine Therapy Initiation for Veterans with Subclinical Hypothyroidism
- Association of Thyroid Function With Suicide Ideation/Attempt -A Systematic Review and Meta-analysis
Showing 5 of 6 shared publications
Rozalina G. McCoy
Mayo Clinic (US)
5 shared publications
- Thyroid hormone treatment among pregnant women with subclinical hypothyroidism: US national assessment
- Effect of metformin on microvascular outcomes in patients with type 2 diabetes: A systematic review and meta-analysis
- Variation in treatment practices for subclinical hypothyroidism in pregnancy: US national assessment
- Treatment burden and perceptions of glucose-lowering therapy among people living with diabetes
- Documentation of hypoglycemia assessment among adults with diabetes during clinical encounters in primary care and endocrinology practices
Lakshmi Menon
University of Arkansas for Medical Sciences
5 shared publications
In database
- Association of Thyroid Function with Suicidal Behavior: A Systematic Review and Meta-Analysis
- Association of Thyroid Function with Posttraumatic Stress Disorder: a Systematic Review and Meta-Analysis
- An Unusual Case of Metastatic Follicular Thyroid Cancer 40 Years after Initial Diagnosis
- Plasma levels of anti phosphocholine IgM antibodies are negatively correlated with bone mineral density in humans
- Association of Thyroid Function With Suicide Ideation/Attempt -A Systematic Review and Meta-analysis
Omar El Kawkgi
Mayo Clinic (US)
5 shared publications
- Levothyroxine Use in the United States, 2008-2018
- Patient Experiences and Perceptions Associated with the Use of Desiccated Thyroid Extract
- Determinants for Thyroid Hormone Replacement Therapy in Subclinical Hypothyroidism: A Multicenter Electronic Health Records-Based Study
- Individualized Graves’ disease remission rates conversations: a videographic analysis of medical encounters
- SUN-432 Utilizing Patient Online Forums to Capture Experiences and Perceptions Associated with the Use of Desiccated Thyroid Extract
Hooman Motahari
University of Arkansas for Medical Sciences
5 shared publications
In database
- Consequences of Severe Iodine Deficiency in Pregnancy: Evidence in Humans
- Association of Thyroid Function with Suicidal Behavior: A Systematic Review and Meta-Analysis
- Discontinuation of levothyroxine therapy in patients with subclinical hypothyroidism: a pilot randomized clinical trial
- Most Patients with COVID-19 Are Euthyroid
- THU664 Discontinuation Of Low-dose Levothyroxine Therapy For Patients With Subclinical Hypothyroidism Is Feasible: A Pilot, Randomized, Double-blind, Placebo-controlled Trial
Elena Ambrogini
Central Arkansas Veterans Healthcare System
5 shared publications
In database
- Effect of Androgen Suppression on Clinical Outcomes in Hospitalized Men With COVID-19
- Knowledge, Attitudes, Beliefs, and Treatment Burden Related to the Use of Levothyroxine in Hypothyroid Pregnant Women in the United States
- Discontinuation of levothyroxine therapy in patients with subclinical hypothyroidism: a pilot randomized clinical trial
- Plasma levels of anti phosphocholine IgM antibodies are negatively correlated with bone mineral density in humans
- THU664 Discontinuation Of Low-dose Levothyroxine Therapy For Patients With Subclinical Hypothyroidism Is Feasible: A Pilot, Randomized, Double-blind, Placebo-controlled Trial
Arwa Albashaireh
University of Arkansas for Medical Sciences
5 shared publications
In database
- Discontinuation of levothyroxine therapy in patients with subclinical hypothyroidism: a pilot randomized clinical trial
- Stopping Levothyroxine Therapy in Subclinical Hypothyroidism, Perhaps We Could Start a Trend
- Iron Deficiency Is Associated with Maternal Hypothyroxinemia in the Third Trimester of Pregnancy
- Thyroid Function Classification in Early Pregnancy Varies Considerably Across Repeated Testing Within an Interval of a Few Weeks
- THU664 Discontinuation Of Low-dose Levothyroxine Therapy For Patients With Subclinical Hypothyroidism Is Feasible: A Pilot, Randomized, Double-blind, Placebo-controlled Trial
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