Match tier Listed
Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-08-08

Todd J. Spears

Researcher

UAMS

Unknown Researcher

1 h-index 4 pubs 28 cited

Research Areas

Biomedical Subjects

  • Pyroptosis
  • Bacterial Infections
  • Humans
  • Immunity, Innate
  • Macrophages
  • Neutrophils
  • Inflammasomes
  • Cytidine Deaminase
  • DNA
  • Proto-Oncogene Proteins c-myc
  • Proto-Oncogene Proteins c-bcl-2
  • Animals
  • Epithelial Cells
  • Gram-Negative Bacteria
  • Gram-Negative Bacterial Infections

OverviewAI-generated summary

Todd J. Spears' research focuses on inflammasome-mediated pyroptosis as a defense mechanism against pathogenic bacteria. Pyroptosis is a highly inflammatory form of programmed cell death that plays a critical role in the innate immune system's response to infection. His work investigates the molecular pathways involved in this process and its implications for combating bacterial pathogens. This research contributes to understanding host-pathogen interactions and potential therapeutic strategies for infectious diseases.

Metrics

  • h-index: 1
  • Publications: 4
  • Citations: 28

Selected Publications

  • DNA secondary structures in <i>BCL2</i> and <i>MYC</i> elicit activation-induced cytidine deaminase binding and activity (2026)
    Nucleic Acids Research 1 citation DOI OpenAlex
  • Inflammasome‐mediated pyroptosis in defense against pathogenic bacteria (2024)
    Immunological Reviews 27 citations DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

2 Collaborators 1 Institution 1 Country

Top Collaborators

Similar Researchers

Based on overlapping research topics

Elisabet Borsheim University of Arkansas for Medical Sciences
Immune Response and Inflammation Microbial infections and disease research Disease Mechanisms Research
Strong match 4 shared topics
Natalie Black University of Arkansas for Medical Sciences
Immune Response and Inflammation Microbial infections and disease research Disease Mechanisms Research
Strong match 4 shared topics
Mark A. Worley University of Arkansas for Medical Sciences
Immune Response and Inflammation Microbial infections and disease research Disease Mechanisms Research
Strong match 4 shared topics
Michael Soulsby University of Arkansas for Medical Sciences
Immune Response and Inflammation Microbial infections and disease research Disease Mechanisms Research
Strong match 4 shared topics
Mary A. Curtis University of Arkansas for Medical Sciences
Immune Response and Inflammation Microbial infections and disease research Disease Mechanisms Research
Strong match 4 shared topics
Allison C. Anthony University of Arkansas for Medical Sciences
Microbial infections and disease research Disease Mechanisms Research Host-Pathogen Interactions
Strong match 4 shared topics